¹Catholic University of Sacred Heart, Internal Medicine Department, Gastroenterology Division, Rome, Italy, ²Case Western Reserve University, Pathology, Cleveland, USA

¹Francis Crick Institute, Immunosurveillance Lab, London, UK, ²King's College London, DIIID, London, UK, ³Guy's and St Thomas Foundation Trust, Department of Gastroenterology, London, UK, ⁴King's College London, DTIMB, London, UK

University of Erlangen-Nuremberg, Department of Medicine I, Erlangen, Germany

Centre for Colorectal Disease, St. Vincent's University Hospital, Univsersity College Dublin, Dublin, Ireland

¹Hospital Universitari de Tarragona Joan XXIII. Institut d´Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili, Tarragona, Spain, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain, Tarragona, Spain, ²Servicio de Endocrinología y Nutrición, Campus Teatinos s/n, Hospital Clínico Universitario Virgen de la Victoria, 29010, Málaga, Spain, CIBEROBN, Instituto de Salud Carlos III, Madrid, Spain, ³Hospital Joan XIII, Digestive Unit, Tarragona, Spain, ⁴Colorectal Surgery Unit, General Surgery Service, Hospital Vall d’Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain, ⁵Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain. ⁶CIBER de Diabetes y Enfermedades Metabolicas Asociadas, Barcelona, Spain. Departamento de Bioquimica i Biomedicina Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain, ⁷Hospital Joan XIII, Colorectal Surgery Unit, Tarragona, Spain

¹University Hospital Zurich, Division of Gastroenterology and Hepatology, Zurich, Switzerland, ²University Hospital Zurich, Zurich, Switzerland

¹GIGA-R, Uliege, Translational Gastroenterology, Liège, Belgium, ²CHU de Liège, Pathological anatomy, Liège, Belgium, ³CHU de Liège, Hepato-gastroenterology and digestive oncology, Liège, Belgium, ⁴Uliege,Laboratory of mass spectrometry, Chemistry, Liège, Belgium, ⁵GIGA proteomic facility, Uliege, GIGA, Liège, Belgium

¹Kath. Krankenhaus Hagen, Hagen, Germany, ²Klinikum Bogenhausen, München, Germany, ³Jagiellonian University Medical College, Krakow, Poland, ⁴Royal London Hospital, London, UK, ⁵Royal Hospital for Children, Glasgow, UK, ⁶Villafranca del Hospital Universitario de Basurto, Bilbao, Spain, ⁷Canberra Hospital, Canberra, Australia, ⁸Cabinet Medical Créteil, Paris, France, ⁹Cochin Hospital, Paris, France, ¹⁰CHU Dinant-Godinne, Department of Gastroenterology, Yvoir, Belgium, ¹¹Triemli Hospital, Zürich, Switzerland, ¹²University and Medical School of Ioannina, Ioannina, Greece, ¹³Hospital Universitari Germans Trias I Pujol, Badalona, Spain, ¹⁴CIBEREHD, Madrid, Spain

¹GIGA-R, ULiège, Translational Gastroenterology, Liège, Belgium, ²CHU de Liège, Hepato-Gastroenterology and Digestive oncology, Liège, Belgium, ³CHU de Liège, Pathological anatomy and cytology, Liège, Belgium, ⁴GIGA proteomic facility, ULiège, Liège, Belgium, ⁵ULiège, Laboratory of mass spectrometry, Chemistry, Liège, Belgium, ⁶GIGA-R, ULiège, Laboratory of Thrombosis and Hemostasis, Liège, Belgium, ⁷ULiège, Mammalian cell culture laboratory, Liège, Belgium, ⁸CHU de Liège, Abdominal Surgery Department, Liège, Belgium, ⁹CHC de Liège, Gastroenterology, Liège, Belgium, ¹⁰CHR Citadelle de Liège, Gastroenterology and Digestive oncology, Liège, Belgium

Academic Medical Center (AMC), Department of Surgery, Amsterdam, The Netherlands

¹Service of Gastroenterology and Hepatology, CHUV, University of Lausanne, Lausanne, Switzerland, ²Department of Oncology, CHUV, University of Lausanne, Lausanne, Switzerland, ³Institute of Pathology, CHUV, Lausanne, Switzerland, ⁴Clinic for Visceral Surgery and Medicine, Department of Gastroenterology; University Hospital Bern Inselspital, Bern, Switzerland

¹BSRC "Alexander Fleming", Vari, Greece, ²University of Cologne, Institute of Genetics, Cologne, Germany, ³University of Athens, School of Medicine, Athens, Greece

¹King's College London, Nutritional Sciences, London, UK, ²Queen Mary University of London, Centre for Immunobiology, London, UK, ³Institut National de la Recherche Agronomique, Microbiology, Paris, France, ⁴King's College London, Dental Institute, London, UK, ⁵Guy's and St Thomas' NHS Foundation Trust, Nutrition and dietetics, London, UK, ⁶Barts Health NHS Trust, Gastroenterology, London, UK, ⁷Guy's and St Thomas' NHS Foundation Trust, Gastroenterology, London, UK

¹Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, USA, ²Hospital Beatriz Ângelo, Gastroenterology, Loures, Portugal, ³Icahn School of Medicine at Mount Sinai, Precision Immunology Institute, New York, USA, ⁴Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences, New York, USA, ⁵Icahn School of Medicine at Mount Sinai, Institute for Genomics and Multiscale Biology, New York, USA

¹Klinikum rechts der Isar, II. Med. Klinik, Munich, Germany, ²Institute of Med. Microbiology, TUM, Munich, Germany, ³University of California, San Diego, San Diego, USA, ⁴Memorial Sloan Kettering Cancer Center, New York, USA

¹Sheba Medical Center, Tel Hashomer, Israel, ²Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

¹Rabin Medical Center, Division of Gastroenterology, Petah Tikva, Israel, ²Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ³Clalit health services, Jerusalem, Israel, ⁴Sheba Medical Center affiliated with Sackler faculty of medicine Tel Aviv University, Internal Medicine T, Ramat Gan, Israel

¹St Mark's Academic Institute, Robin Phillip's Fistula Research Unit, London, UK, ²King's College London, Florence Nightingale School of Nursing and Midwifery, London, UK, ³University of Greenwich, Adult Nursing and Paramedic Science, London, UK, ⁴St Mark's Hospital, Department of Surgery, London, UK, ⁵University Hospitals Birmingham, Surgery, Birmingham, UK, ⁶Homerton University Hospital, Macmillan Cancer Care, London, UK, ⁷London, London, UK, ⁸St Mark's Hospital, Department of Radiology, London, UK, ⁹St Mark's Hospital, Department of IBD, London, UK

¹St Mark's Academic Institute, Robin Phillip's Fistula Research Unit, London, UK, ²King's College London, Florence Nightingale School of Nursing and Midwifery, London, UK, ³University of Greenwich, Adult Nursing and Paramedic Science, London, UK, ⁴St Mark's Hospital, Department of Surgery, London, UK, ⁵University Hospitals Birmingham, Surgery, Birmingham, UK, ⁶Homerton University Hospital, Macmillan Cancer Care, London, UK, ⁷London, London, UK, ⁸St Mark's Hospital, Department of Radiology, London, UK, ⁹St Mark's Hospital, Department of IBD, London, UK

Odense Universitets Hospital, Department of Medical Gastroenterology, Odense, Denmark