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P834: Proteus is a key candidate in the pathogenesis of Crohn’s disease: mucosa, stool genomics and functional analysis: the ENIGMA study

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Zhang*1,2, E. Berendsen3, E. Hoedt3, Q. Liu1,2, F. Zhang1,2, Z. Xu1,2, A. Hamilton4,5, A. W. O’ Brien4,5, J. Ching1, J. J. Sung1, M. A. Kamm4,5, M. Morrison3, J. Yu1,2, S. C. Ng1

1The Chinese University of Hong Kong, Medicine & Therapeutics, Hong Kong, Hong Kong, 2The Chinese University of Hong Kong, Institute of Digestive Disease, Hong Kong, Hong Kong, 3The University of Queensland Diamantina Institute, Faculty of Medicine, Brisbane, Australia, 4St Vincent's Hospital, Department of Gastroenterology, Melbourne, Australia, 5The University of Melbourne, Department of Medicine, Melbourne, Australia

P835: Characterisation of fungal microbiota in a Norwegian IBD cohort

ECCO '19 Copenhagen

Year: 2019
Authors:

A. van Beelen Granlund*1,2, S. Thorsvik1,3, I. Catalán-Serra1,4, V. Beisvag2, D. Underhill1,5,6, A. K. Sandvik1,3

1Norwegian University of Science and Technology, Centre for Molecular Inflammation Research, Trondheim, Norway, 2Norwegian University of Science and Technology, Department of Clinical and Molecular Medicine, Trondheim, Norway, 3St Olav’s Hospital, Department of Gastroenterology, Trondheim, Norway, 4Levanger Hospital, Department of Medicine [Gastroenterology], Levanger, Norway, 5Cedars-Sinai Medical Center, Research Division of Immunology, Los Angeles, CA, USA, 6Cedars-Sinai Medical Center, F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Los Angeles, CA, USA

P836: The predictive role of gut microbiota in treatment response to vedolizumab and ustekinumab in inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

C. Caenepeel*1, S. Vieira-Silva2, B. Verstockt1,3, M. Ferrante1,3, J. Raes2, S. Vermeire1,3

1KU Leuven, TARGID, Leuven, Belgium, 2Rega Institute for Medical Research, Microbiology and Immunology, Leuven, Belgium, 3University hospitals Leuven, Gastroenterology and Hepatology, Leuven, Belgium

P837: The common food additives sodium sulfite and polysorbate 80 have a profound inhibitory effect on the commensal, anti-inflammatory bacterium Faecalibacterium prausnitzii: the ENIGMA study

ECCO '19 Copenhagen

Year: 2019
Authors:

J. J. Jimenez Loayza1,2, E. M. Berendsen*1,2, J-J. Teh1,2, E. C. Hoedt1,2,3, J. Zhang4,5, Q. Liu4,5, A. L. Hamilton6, A. Wilson-O'Brien6, G. L. Trakman6, W. Lin4,5, W. Tang4,5, J. Ching4,5, L. M. H. Or4,5, J. J. Sung4,5, J. Yu4,5, S. C. Ng4,5,7, M. A. Kamm6, M. Morrison1,2

1The University of Queensland Diamantina Institute, Faculty of Medicine, Brisbane, Australia, 2Translational Research Institute, Brisbane, Australia, 3University College Cork, APC Microbiome Ireland, Cork, Ireland, 4The Chinese University of Hong Kong, Department of Medicine and Therapeutics, Hong Kong, Hong Kong, 5The Chinese University of Hong Kong, LKS Institute of Health Sciences, Institute of Digestive Disease and State Key Laboratory of Digestive Diseases, Hong Kong, Hong Kong, 6The University of Melbourne and St Vincent's Hospital, Melbourne, Department of Medicine and Department of Gastroenterology, Melbourne, Australia, 7The Chinese University of Hong Kong, Centre for Gut Microbiota Research, Hong Kong, Hong Kong

P838: Effects of microbial metabolites on human intestinal epithelium

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Mayorgas*1, E. Ferrer-Picón1, I. Dotti1, A. Corraliza1, N. Planell2, M. Esteller1,2, A. Carrasco2,3, M. C. Masamunt1, M. Esteve2,3, J. Panés1, A. Salas1

1IDIBAPS, Barcelona, Spain, 2CIBERehd, Madrid, Spain, 3Hospital Universitari Mutua de Terrassa, Terrassa, Spain

P840: Dietary interventions rapidly alter metabolomics profile of patients with inflammatory bowel disease after pouch surgery

ECCO '19 Copenhagen

Year: 2019
Authors:

L. Godny*1,2, L. Reshef3, T. Pfeffer-Gik1,2, K. Rabinowitz1,2, I. Goren1,2, K. Yadgar1, K. Zonensain1, R. Barkan1, H. Yanai1,2, U. Gophna3, H. Tulchinsky4, I. Dotan1,2

1Rabin Medical Center, Division of Gastroenterology, Petah-Tikva, Israel, 2Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv, Israel, 3Tel Aviv University, Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv, Israel, 4Tel Aviv Sourasky Medical Center, Proctology Unit, Department of Surgery, Tel Aviv, Israel

P841: Small intestinal bacterial overgrowth in patients with Crohn’s disease is not only associated with a more severe disease, but is also marked by dramatic changes in the gut microbiome

ECCO '19 Copenhagen

Year: 2019
Authors:

Y. Kulygina1, M. Osipenko1, M. Skalinskaya2, T. Alikina3, M. Kabilov3, V. Lukinov4, S. Sitkin*2,5

1Novosibirsk State Medical University, Department of Internal Diseases, Novosibirsk, Russian Federation, 2North-Western State Medical University named after I.I. Mechnikov, Department of Internal Diseases, Gastroenterology and Dietetics named after S.M. Ryss, St. Petersburg, Russian Federation, 3Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russian Federation, 4Institute of Computational Mathematics and Mathematical Geophysics SB RAS, Novosibirsk, Russian Federation, 5State Research Institute of Highly Pure Biopreparations of FMBA, Department of Microbiology, St. Petersburg, Russian Federation

P842: Multi-omics analysis suggests an active role of fungi in Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Frau*1, U. Z. Ijaz2, R. Hough1, B. J. Campbell1, J. G. Kenny3, N. Hall4, J. Anson5, A. C. Darby3, C. S. J. Probert1

1University of Liverpool, Cellular and Molecular Physiology, Liverpool, UK, 2University of Glasgow, School of Engineering, Glasgow, UK, 3University of Liverpool, Centre for Genomic Research (CGR), Liverpool, UK, 4Earlham Institute, Norwich, UK, 5Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK

P843: Post-vaccination kinetics of antibodies against hepatitis B surface antigen in inflammatory bowel disease patients: a single-centre cohort study

ECCO '19 Copenhagen

Year: 2019
Authors:

I. Dimas1,2, E. Voudoukis2, G. Paspatis2, K. Karmiris*2

1Naval Hospital of Crete, Department of Gastroenterology, Chania, Greece, 2Venizelio General Hospital, Department of Gastroenterology, Heraklion, Greece

P844: Mucosa associated candida in ulcerative colitis: prevalence and relationship to disease severity

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Shah*1, U. Dutta1, S. Rudramurthy2, A. Chakrabarti2, P. Sharma1, P. Popli1, R. Srinivasan3, A. Das4, S. K. Sinha1, V. Sharma1, N. Dhaka1, H. Madhavdhare1, R. Kochhar1

1PGIMER, Gastroenterology, Chandigarh, India, 2PGIMER, Microbiology, Chandigarh, India, 3PGIMER, Cytology, Chandigarh, India, 4PGIMER, Pathology, Chandigarh, India

P845: The changes of intestinal microbiota composition may predict the response of anti-TNF α in patients with Crohn's disease

ECCO '19 Copenhagen

Year: 2019
Authors:

G. Seong*1, S. N. Hong1, T. J. Kim1, E. R. Kim1, D. K. Chang1, Y-H. Kim1

1Samsung Medical Center, Seoul, South Korea

P846: Elafin-expressed Escherichia coli Nissle 1917 ameliorates experimental colitis in mice

ECCO '19 Copenhagen

Year: 2019
Authors:

G. Teng*1, L. Yun1, W. Ting1, W. Huahong1

1Peking University First Hospital, Gastroenterology, Beijing, China

P847: Perceptions of faecal microbiota transplantation in a paediatric ulcerative colitis population (PediFETCh Trial)

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Popov*1, E. Hartung2,3, L. Hill2,4, U. Chauhan5, N. Pai2

1University College Cork, College of Medicine & Health, Cork, Ireland, 2McMaster University, Paediatrics, Division of Gastroenterology & Nutrition, Hamilton, Canada, 3Humber College, School of Health Sciences, Toronto, Canada, 4University of Cape Town, Exercise Science & Sports Medicine, Faculty of Health Sciences, Cape Town, South Africa, 5Hamilton Health Sciences, Medicine, Division of Gastroenterology, Hamilton, Canada

P848: Latent tuberculosis and active tuberculosis infection in patients with inflammatory bowel disease treating by biological agents: an experience of a medical centre in Taiwan

ECCO '19 Copenhagen

Year: 2019
Authors:

H-C. Lai*1, K-S. Cheng2,3, C-H. Chang2, C-L. Feng2, T-W. Chen3,4, J-W. Chou2,3,5

1China Medical University Hospital, Department of Chinese Medicine, Taichung, Taiwan, 2China Medical University Hospital, Division of Gastroenterology and Hepatology, Taichung, Taiwan, 3China Medical University, School of Medicine, Taichung, Taiwan, 4China Medical University Hospital, Department of Pathology, Taichung, Taiwan, 5The Taiwan Society of Inflammatory Bowel Disease, Taipei, Taiwan

P849: Urease-positive proteobacteria in Crohn’s disease identified by novel ex vivo mucosal microbe culture combined with metagenomic sequencing (MC-MGS): the ENIGMA study

ECCO '19 Copenhagen

Year: 2019
Authors:

E. M. Berendsen*1,2, E. C. Hoedt1,2,3, J-J. Teh1,2, J. Zhang4,5, F. Zhang4,5, Q. Liu4,5, A. L. Hamilton6, J. Ching4,5, J. J. Sung4,5, J. Yu4,5, S. C. Ng4,5,7, M. A. Kamm6, M. Morrison1,2

1The University of Queensland Diamantina Institute, Faculty of Medicine, Brisbane, Australia, 2Translational Research Institute, Brisbane, Australia, 3University College Cork, APC Microbiome Ireland, Cork, Ireland, 4The Chinese University of Hong Kong, Department of Medicine and Therapeutics, Hong Kong, Hong Kong, 5The Chinese University of Hong Kong, LKS Institute of Health Sciences, Institute of Digestive Disease and State Key Laboratory of Digestive Diseases, Hong Kong, Hong Kong, 6The University of Melbourne and St Vincent's Hospital, Melbourne, Department of Medicine and Department of Gastroenterology, Melbourne, Australia, 7The Chinese University of Hong Kong, Centre for Gut Microbiota Research, Hong Kong, Hong Kong

P850: Measles virus immune status in a cohort of Spanish patients with inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Gómez-Outomuro1, A. Castaño-García1, P. Flórez-Díez1, R. de Francisco*1,2, M. Rodriguez3, I. Huerta-González4, I. Pérez-Martínez1, S. Martínez-González1, M. Fernández-Prada5, A. Suárez1,2, S. Riestra1,2

1Hospital Universitario Central de Asturias, Gastroenterology, Oviedo, Spain, 2Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain, 3Hospital Universitario Central de Asturias, Laboratory of Medicine, Oviedo, Spain, 4Regional Ministry of Health of the Principality of Asturias, Department of Epidemiological Surveillance, Oviedo, Spain, 5Hospital Universitario Central de Asturias, Department of Preventive Medicine and Public Health, Oviedo, Spain

P851: Effects of manipulation of the gut microbiota on colon tumorigenesis in AOM-DSS model

ECCO '19 Copenhagen

Year: 2019
Authors:

C. S. Eun*1, D. S. Han1, J. G. Lee1, C. H. Park1

1Hanyang University Guri Hospital, Guri, South Korea

P852: Characterisation of Crohn’s disease mucosa-associated microbiota by a novel combination of microbe culture and metagenomic sequencing (MC-MGS): the ENIGMA study

ECCO '19 Copenhagen

Year: 2019
Authors:

E. M. Berendsen*1,2, E. C. Hoedt1,2,3, J-J. Teh1,2, J. Zhang4,5, F. Zhang4,5, Q. Liu4,5, A. L. Hamilton6, A. Wilson-O'Brien6, J. Ching4,5, J. J. Sung4,5, J. Yu4,5, S. C. Ng4,5,7, M. A. Kamm6, M. Morrison1,2

1The University of Queensland Diamantina Institute, Faculty of Medicine, Brisbane, Australia, 2Translational Research Institute, Brisbane, Australia, 3University College Cork, APC Microbiome Ireland, Cork, Ireland, 4The Chinese University of Hong Kong, Department of Medicine and Therapeutics, Hong Kong, Hong Kong, 5The Chinese University of Hong Kong, LKS Institute of Health Sciences, Institute of Digestive Disease and State Key Laboratory of Digestive Diseases, Hong Kong, Hong Kong, 6The University of Melbourne and St Vincent's Hospital, Melbourne, Department of Medicine and Department of Gastroenterology, Melbourne, Australia, 7The Chinese University of Hong Kong, Centre for Gut Microbiota Research, Hong Kong, Hong Kong

P853: The gut microbiota of pregnant inflammatory bowel disease patients shows a low diversity, but stable profile throughout pregnancy

ECCO '19 Copenhagen

Year: 2019
Authors:

J. van der Giessen1, D. Binyamin2, O. Koren2, M. Peppelenbosch1, C. J. van der Woude1, G. M. Fuhler1

1Erasmus Medical Centrum, Gastroenterology and Hepatology, Rotterdam, The Netherlands, 2Bar-Ilan University, The Azrieli Faculty of Medicine, Safed, Israel

P854: Insights into alteration of gut microbiota in inflammatory bowel disease patients with and without Clostridium difficile infection

ECCO '19 Copenhagen

Year: 2019
Authors:

D. Chen1, Y. Li*1, H. Sun1, M. Xiao1, N. Lv2, S. Liang2, B. Tan1, B. Zhu2

1Peking Union Medical College Hospital, Beijing, China, 2Institute of microbiology, Chinese Academy of Science, Beijing, China