¹Umeå University, Department of medical bioscienses, clinical chemistry, Umeå, Sweden, ²Umeå University, Department of pharmacology and clinical neuroscience, Umeå, Sweden, ³Umeå University, Department of public health and clinical medicine, Umeå, Sweden

¹University of Rome 'Tor Vergata', Gastroenterology, Rome, Italy

¹Hospital Vall d′Hebron, Gastroenterology Department, Barcelona, Spain, ²Complejo Hospitalario de Pontevedra, Gastroenterology Unit, Pontevedra, Spain, ³Hospital Clínico Universitario, Unidad de Gastroenterología, Valencia, Spain, ⁴Hospital Universitario Puerta de Hierro, Servicio de Gastroenterologia, Madrid, Spain, ⁵Medical Department, MSD, Madrid, Spain, ⁶Hospital Universitari Germans Trias i Pujol, Gastroenterology Unit, Badalona, Spain, ⁷Spanish Association of patients with Crohn′s disease and Ulcerative colitis, Madrid, Spain, ⁸Institut Universitari Parc Taulí, Digestive Unit, Sabadell, Spain

¹Hvidovre University Hospital, The Paediatric Department, Hvidovre, Denmark, ²Hvidovre University Hospital, The GastroUnit, Hvidovre, Denmark, ³Herlev Hospital, The Department of Pathology, Herlev, Denmark, ⁴Tampere University Hospital, The Paediatric Department, Tampere, Finland

¹Bispebjerg and Frederiksberg Hospital, Center for Clinical Research and Prevention, Copenhagen, Denmark, ²University of Glasgow, Glasgow, UK, ³Bispebjerg and Frederiksberg Hospital, Abdominal Centre K, Copenhagen, Denmark

¹Janssen Immunology, Birkerød, Denmark, ²Janssen Immunology, High Wycombe, UK, ³Leo Pharma, Ballerup, Denmark, ⁴Incentive, Holte, Denmark, ⁵North Zealand University Hospital, Frederikssund, Denmark, ⁶Odense University Hospital, Odense, Denmark

¹Instituto de Investigación Sanitaria Galicia Sur. Hospital Alvaro Cunqueiro. EOXI Vigo, Gastroenterology, Vigo, Spain, ²Gentofte Hospital, Medical Gastroenterology, Copenhagen, Denmark, ³University Hospital Ioannina, 1st Division of Internal Medicine and Hepato-Gastroenterology Unit, Ioannina, Greece, ⁴State University of Medicine and Pharmacy of the Republic of Moldova, Gastroenterology, Chisinau, Moldova, Republic of, ⁵Morgagni Hospital, Gastroenterology and Digestive Endoscopy, Forli, Italy, ⁶Semmelweis University, 1st Department of Medicine, Budapest, Hungary, ⁷University of Medicine ‘Victor Babes’, Clinic of Gastroenterology, Timisoara, Romania, ⁸Moscow Regional Research Clinical Institute, Gastroenterology, Moscow, Russian Federation, ⁹Dronning Ingrids Hospital, Medical Department, Nuuk, Greenland, ¹⁰Lithuanian University of Health Sciences, Institute for Digestive Research, Kaunas, Lithuania, ¹¹Adelaide and Meath Hospital, Gastroenterology, Dublin, Ireland, ¹²Hospital Ceské Budejovice, Gastroenterology, Ceské Budejovice, Czech Republic, ¹³University Hospital Center Zagreb, Gastroenterology, Zagreb, Croatia, ¹⁴Hospital de São João, Porto; Institute of Pharmacology and Therapeutics, Oporto Medical School and Institute for molecular and cell biology, Gastroenterology, Porto, Portugal, ¹⁵21Landspitali - The National University Hospital of Iceland, Gastroenterology, Reykjavik, Iceland, ¹⁶Karolinska Institutet, GastroCentrum, Stockholm, Sweden, ¹⁷Amiens University and Hospital, Epimad Registry, Gastroenterology Unit, Amiens, France, ¹⁸Charles University, IBD Center ISCARE, Prague, Czech Republic, ¹⁹Herning Central Hospital, Medicine, Herning, Denmark, ²⁰Private Practice, Nicosia, Cyprus, ²¹Mater Dei Hospital, Gastroenterology, Msida, Malta, ²²St Vincent's Hospital, Gastroenterology, Melbourne, Australia, ²³AOU Careggi Regional Referral Center for Inflammatory Bowel Disease, Gastroenterology, Florence, Italy, ²⁴Soroka Medical Center and Ben Gurion University of the Negev, Gastroenterology and Hepatology, Beer Sheva, Israel, ²⁵Slagelse Hospital, Gastroenterology, Slagelse, Denmark, ²⁶Arhus University Hospital, Medicine V (Hepatology and Gastroenterology), Arhus, Denmark, ²⁷Tartu University Hospital, Endocrinology and Gastroenterology, Tartu, Estonia, ²⁸Azienda Ospedaliera di Padova, Surgery, Oncology and Gastroenterology, Padova, Italy, ²⁹Faculty of Medicine and Health, Gastroenterology, Orebro, Sweden, ³⁰Tampere University Hospital, Gastroenterology and Alimentary Tract Surgery, Tampere, Finland, ³¹St. Mark's Hospital, Imperial College London, Gastroenterology, London, UK, ³²The National Hospital of the Faroe Islands, Medical Department, Torshavn, Faroe Islands, ³³Regional Hospital of Viborg, Medical Department, Viborg, Denmark, ³⁴Hull and East Yorkshire NHS Trust, IBD Unit, Hull, UK, ³⁵North Zealand University Hospital, Gastroenterology, Frederikssund, Denmark

¹Cleveland Clinic, Colon and Rectal Surgery, Cleveland, USA, ²Cleveland Clinic, Quantitative Health Sciences, Cleveland, USA

¹Agaplesion Markus Hospital, Frankfurt/Main, Germany, ²Adelphi Real World, Bollington, UK, ³Pfizer Inc., Groton, CT, USA, ⁴Pfizer Inc., Collegeville, PA, USA, ⁵Pfizer Germany GmbH, Berlin, Germany, ⁶Pfizer Inc., New York, NY, USA

¹Ospedale San Filippo Neri, IBD Unit, Roma, Italy, ²UOC Gastroenterologia ed Endoscopia Digestiva Diagnostica e Operativa A.O. San Camillo-Forlanini, Roma, Italy, ³IBD Unit, Presidio Columbus Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica, Rome, Italy, ⁴Statistician - Italian Group for the study of Inflammatory Bowel Disease, Firenze, Italy, ⁵U.O. Gastroenterologia, Ospedale di Rho, ASST Rhodense, Rho (Milano), Italy, ⁶Sezione di Gastroenterologia, Azienda Policlinico Universitaria Bari, Bari, Italy, ⁷Department of Surgical Sciences, University of Turin, Torino, Italy, ⁸IBD Centre, Humanitas Clinical and Research Centre; *Department of Biomedical Sciences, Humanitas University, Rozzano (Milano), Italy, ⁹SC Gastroenterologia Ospedale Brotzu, Cagliari, Italy, ¹⁰University of Genoa, Policlinico San Martino Department of internal medicine, Genova, Italy, ¹¹UOC Gastroenterologia AOU Mater Domini, Catanzaro, Italy, ¹²Divisione di Gastroenterologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Roma, Italy, ¹³UOC Gastroenterologia Ospedale San Nicola Pellegrino, Trani, Italy, ¹⁴Department of New Technologies and Translational Research in Medicine and Surgery, University of Pisa, Pisa, Italy, ¹⁵Dipartimento di scienze chirurgiche, oncologiche e gastroenterologiche Università di Padova, Padova, Italy, ¹⁶Ospedale S. Filippo Neri, IBD Unit, Roma, Italy

¹Erasmus MC, University Medical Center, Gastroenterology and hepatology, Rotterdam, The Netherlands, ²Erasmus MC, University Medical Center, Public Health, Rotterdam, The Netherlands, ³Maastricht University Medical Center, Gastroenterology and Hepatology, Maastricht, The Netherlands, ⁴Radboud University Medical Center, Gastroenterology and Hepatology, Nijmegen, The Netherlands, ⁵VU University Medical Center, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁶University Medical Center Utrecht, Gastroenterology and Hepatology, Utrecht, The Netherlands, ⁷Leiden University Medical Center, Gastroenterology and Hepatology, Leiden, The Netherlands, ⁸Academic Medical Center, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁹University Medical Center Groningen, Gastroenterology and Hepatology, Groningen, The Netherlands, ¹⁰Erasmus MC, University Medical Center, Pathology, Rotterdam, The Netherlands, ¹¹Erasmus MC, University Medical Center, Gynaecologic Oncology, Rotterdam, The Netherlands, ¹²PALGA, the nationwide network and registry of histo- and cytopathology in the Netherlands, Houten, The Netherlands

¹Shaare Zedek Medical Center, The Juliet Keidan Institute of Paediatric Gastroenterology and Nutrition, Jerusalem, Israel, ²The Hebrew University- Hadassah Medical Center, Braun School of Public and Community Medicine, Jerusalem, Israel, ³Clalit Health Services, Clalit Research Institute, Chief’s Office, Tel Aviv, Israel, ⁴Maccabi Healthcare Services, Tel Aviv, Israel, ⁵Meuhedet Health Services, Tel Aviv, Israel, ⁶Leumit Health Services, Tel Aviv, Israel, ⁷Rambam Health Care Campus, Department of Gastroenterology, Haifa, Israel, ⁸Chaim Sheba Medical Center, Department of Gastroenterology, Tel Hashomer, Israel, ⁹Faculty of Health Sciences,Ben-Gurion University of the Negev, Department of Gastroenterology and Hepatology, Beer Sheva, Israel, ¹⁰Rabin Medical Center, Division of Gastroenterology, Petah Tivka, Israel, ¹¹Hadassah Medical Center, Hebrew University, Institute of Gastroenterology and Liver Diseases, Jerusalem, Israel

¹Hospital Beatriz Ângelo, Gastroenterology, Loures, Portugal, ²Farncombe Family Digestive Health Research Institute, Ontario, Canada, ³Faculty of Medicina of Lisbon, Lisboa, Portugal

¹Beth Israel Deaconess Medical Center, Harvard Medical School, Division of Gastroenterology and Hepatology, Boston, USA, ²Stanford University School of Medicine, Division of Gastroenterology and Hepatology, Stanford, USA, ³Herlev Hospital, University of Copenhagen, Department of Gastroenterology, Copenhagen, Denmark

¹Samsung Medical Center, Seoul, South Korea

¹GlaxoSmithKline, Value Evidence and Outcomes, Collegeville, USA, ²GlaxoSmithKline, Value Evidence and Outcomes, Stevenage, UK, ³Adelphi Real World, Macclesfield, UK

¹Hospital Universitario de La Princesa, ISS-IP, Universidad Autónoma de Madrid and CIBEREHD, Gastroenterology Unit, Madrid, Spain, ²Hospital Universitario Clínico de Santiago, Gastroenterology Unit, Santiago de Compostela, Spain, ³Hospital Universitario Reina Sofía and IMIBIC, Gastroenterology Unit, Córdoba, Spain, ⁴Hospital Universitario de Galdakao, Gastroenterology Unit, Galdakao, Spain, ⁵Hospital Universitario de Gran Canaria Doctor Negrín, Gastroenterology Unit, Las Palmas de Gran Canaria, Spain, ⁶Mutua Terrasa, Gastroenterology Unit, Tarrasa, Spain, ⁷Hospital San Pedro, Gastroenterology Unit, Logroño, Spain, ⁸Hospital Universitario Son Espases, Gastroenterology Unit, Palma de Mallorca, Spain, ⁹Hospital Lozano Blesa, IIS Aragón and CIBERehd, Gastroenterology Unit, Zaragoza, Spain, ¹⁰Hospital General Universitario de Ciudad Real, Gastroenterology Unit, Ciudad Real, Spain, ¹¹Hospital Universitario y Politécnico de La Fe and CIBEREHD, Gastroenterology Unit, Valencia, Spain, ¹²Hospital Universitario Central de Asturias, Gastroenterology Unit, Oviedo, Spain, ¹³Hospital Universitario Marqués de Valdecilla, Gastroenterology Unit, Santander, Spain, ¹⁴Hospital San Pedro de Alcántara, Gastroenterology Unit, Cáceres, Spain, ¹⁵Complejo Hospitalario de Navarra, Gastroenterology Unit, Pamplona, Spain, ¹⁶Hospital Universitario de Burgos, Gastroenterology Unit, Burgos, Spain, ¹⁷Hospital General Universitario Morales Meseguer, Gastroenterology Unit, Murcia, Spain, ¹⁸Universidad Autónoma de Madrid/IdiPaz and CIBERESP, Department of Preventive Medicine and Public Health, Madrid, Spain

¹Amsterdam UMC, Department of Surgery and Gastroenterology, Amsterdam, The Netherlands, ²Spaarne Gasthuis, Department of Internal medicine, Hoofddorp, The Netherlands, ³Amsterdam UMC, Clinical Research Unit, Amsterdam, The Netherlands, ⁴Amsterdam UMC, Department of Surgery, Amsterdam, The Netherlands

¹Singapore General Hospital, Gastroenterology, Singapore, Singapore, ²Duke-NUS Medical School, Singapore, Singapore, ³SengKang General Hospital, Singapore, Singapore

¹Janssen Immunology, Birkerød, Denmark, ²Janssen Immunology, High Wycombe, UK, ³Incentive, Holte, Denmark, ⁴Leo Pharma, Ballerup, Denmark, ⁵North Zealand University Hospital, Frederikssund, Denmark, ⁶Odense University Hospital, Odense, Denmark