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P553: Efficacy, safety and cost-efficiency of adalimumab 80 mg every other week in previously intensified IBD patients under treatment with adalimumab 40 mg every week

ECCO '19 Copenhagen

Year: 2019
Authors:

R. Ferreiro-Iglesias*1, A. Jardi1, A. Quiroga1, I. Baston1, J. Gonzalez2, J. M. Giraldez2, I. Zarra2, M. J. Lamas2, J. E. Dominguez-Munoz1, M. Barreiro-de Acosta1

1University Hospital, Gastroenterology, Santiago de Compostela, Spain, 2University Hospital, Pharmacy, Santiago de Compostela, Spain

P554: Point of Care detection of anti-infliximab antibodies in inflammatory bowel disease patients treated with the biosimilar SB2: performance comparison with ELISA

ECCO '19 Copenhagen

Year: 2019
Authors:

R. Atreya1, H. Schmitt1, S. Fischer1, M. F. Neurath1, X. Rekalde2, D. Nagore*2, A. Ametzazurra2

1Friedrich-Alexander-University Erlangen-Nürnberg, Medical Department I, Erlangen, Germany, 2Progenika Biopharma, R&D, Derio, Spain

P555: Deep remission and mucosal healing in IBD patients under immunosuppression with azathioprine and 6-mercaptopurine

ECCO '19 Copenhagen

Year: 2019
Authors:

J. C. Silva*1, A. P. Silva1, A. Rodrigues1, C. Fernandes1, A. Ponte1, J. Rodrigues1, M. Sousa1, A. C. Gomes1, J. Carvalho1

1Centro Hospitalar Vila Nova de Gaia/Espinho, Gastroenterology, Vila Nova de Gaia, Portugal

P556: The prevalence of metabolic bone disease in patients with IBD- preliminary results from POLIBD study

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Sztembis1, D. Piątek2, S. Jarmakiewicz3, P. R. Kiela4, R. Filip*5,6

1Clinical Hospital No. 2, Department of Internal Medicine and Endocrinology, Rzeszow, Poland, 2Medical University of Lublin, Chair and Departament of Conservative Dentistry with Endodontics, Lublin, Poland, 3University of Rzeszów, Poland, Faculty of Medicine, Rzeszów, Poland, 4Steele Children's Research Center, Departament of Pediatrics and Immunology, Tucson, USA, 5Clinical Hospital No. 2 Rzeszow, Departament of Gastroenterology with IBD Unit, Rzeszów, Poland, 6University of Rzeszów, Faculty of Medicine, Rzeszów, Poland

P557: Sustained remission in inflammatory bowel disease patients after discontinuing infliximab; the ongoing reluctance to stop biologics

ECCO '19 Copenhagen

Year: 2019
Authors:

T. Ryan*1, L. Coffey1, A. Mullen1, J. Leyden1, P. MacMathuna1

1Mater Misericordiae University Hospital, Gastroenterology, Dublin, Ireland

P558: Iterative ileocolonic resection for Crohn’s disease: a prospective multi-centric cohort study of the GETAID Chirurgie

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Abdalla1, A. Brouquet2, L. Maggiori3, P. Zerbib4, Q. Denost5, A. Germain6, E. Cotte7, L. Beyer-Berjot8, N. Munoz-Bongrand9, V. Desfourneaux10, A. Rahili11, J-P. Duffas12, K. Pautrat13, C. Denet14, V. Bridoux15, G. Meurette16, J-L. Faucheron17, J. Loriau18, F. Guillon19, E. Vicaut20, S. Benoist2, Y. Panis3, J. Lefevre*1

1Hopital saint antoine, General and Digestive surgery, Paris, France, 2CHU Bicètre, General and Digestive surgery, Le Kremlin-Bicètre, France, 3CHU Beaujon, Colorectal Surgery, Clichy, France, 4CHRU Lille, General Surgery, Lille, France, 5CHU Pessac, Colorectal Surgery, Bordeaux, France, 6CHU Nancy, General and Digestive surgery, Nancy, France, 7CHU Lyon-Sud, General and Digestive surgery, Lyon, France, 8CHU Nord, General and Digestive surgery, Marseille, France, 9CHU St-Louis, General and Digestive surgery, Paris, France, 10CHU Rennes, General and Digestive surgery, Rennes, France, 11CHU Nice, General and Digestive surgery, Nice, France, 12CHU Rangueil, General and Digestive surgery, Toulouse, France, 13CHU Lariboisière, General and Digestive surgery, Paris, France, 14Institut Monsouris, General and Digestive surgery, Paris, France, 15CHRU Rouen, General and Digestive surgery, Rouen, France, 16CHU Nantes, General and Digestive surgery, Nantes, France, 17CHU Grenoble, General and Digestive surgery, Grenoble, France, 18Hopital Saint-Jospeh, General and Digestive surgery, Paris, France, 19CHRU Montpellier, General and Digestive surgery, Montpellier, France, 20URC Fernand-Widal, Unité de Recherche clinique, Paris, France

P559: Real-life experience with long-term maintenance of golimumab in ulcerative colitis patients

ECCO '19 Copenhagen

Year: 2019
Authors:

M. Iborra*1, N. García-Morales1, S. Rubio2, O. Nantes Castillejo2, F. Bertoletti3, E. García-Planella3, M. Calvo4, I. Vera4, C. Taxonera5, C. Alba5, M. Boscá-Watts6, D. Martí-Aguado6, M. P. Ballester Ferrer6, M. Sierra7, N. Cano-Sanz7, N. Mancenido8, R. Pajares-Villarroya8, B. Beltrán1, A. Cañada9, P. Nos1

1Hospital Universitario y Politécnico La Fe, Gastroenterology, Valencia, Spain, 2Complejo Hospitalario de Navarra, Gastroenterology, Pamplona, Spain, 3Hospital de la Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain, 4Hospital Universitario Clínica Puerta de Hierro, Gastroenterology, Madrid, Spain, 5Hospital Clínico San Carlos, Gastroenterology, Madrid, Spain, 6Hospital Clínico Universitario, Gastroenterology, Valencia, Spain, 7Complejo Asistencial Universitario de León, Gastroenterology, León, Spain, 8Hospital Infanta Sofía, San Sebastián de los Reyes, Gastroenterology, Madrid, Spain, 9Hospital Universitario y Politécnico La Fe, Biostatistics and Bioinformatics, Valencia, Spain

P560: Multi-centric randomised study comparing interventional vs. non-interventional treatment for anal fistulas in patient with Crohn’s disease and adalimumab treatment

ECCO '19 Copenhagen

Year: 2019
Authors:

L. Abramowitz1, D. Bouchard2, L. Siproudhis3, F. Pigot*2, P. Roumeguere-Blond4, H. Pillant5, B. Vinson-Bonnet6, J-L. Faucheron7, A. Senejoux8, G. Bonnaud9, G. Meurette10, C. Train11, G. Staumont12

1Chu Bichat, Proctologie, Paris, France, 2Hopital Bagatelle, Proctologie, Bordeaux, France, 3Chu Rennes, Gastroenterologie, Rennes, France, 4Clinique Tivoli, Proctologie, Bordeaux, France, 5Hopital Saint Joseph, Proctologie, Paris, France, 6Ch Poissy, Chirurgie Digestive, Poissy, France, 7Chu Grenoble, Chirurgie Digestive, Grenoble, France, 8Clinique Saint Gregoire, Proctologie, Saint Gregoire, France, 9clinique Ambroise Pare, Gastroenterologie, Toulouse, France, 10Chu Nantes, Chirurgie Digestive, Nantes, France, 11Clinsearch, Statistiques, Bagneux, France, 12Clinique Saint Jean, Gastroenterologie, Toulouse, France

P561: Impact of ustekinumab TDM on clinical practice: a multi-centre, prospective, cross-sectional observational trial—mUST-Decide

ECCO '19 Copenhagen

Year: 2019
Authors:

B. Bressler*1, D. Dajnowiec2, M. Williamson3, K. Karra3, G. Long-Long4, B. Sattin3, W. Afif5

1University of British Columbia, Vancouver, Canada, 2Janssen Inc., Medical Affairs, Canada, Canada, 3Janssen Inc., Medical Affairs, Toronto, Canada, 4Janssen Inc., Research and Development, LLC, Spring House, USA, 5McGill University, Montreal, Canada

P562: Treatment of older inflammatory bowel disease patients; steroid use and escalation to steroid sparing therapy

ECCO '19 Copenhagen

Year: 2019
Authors:

V. Asscher*1, N. Provoost1, L. Meijer1, A. van der Meulen-de Jong1, F. van Deudekom2, S. Mooijaart2,3, J. Maljaars1

1LUMC, Gastroenterology and Hepatology, Leiden, The Netherlands, 2LUMC, Gerontology and Geriatrics, Leiden, The Netherlands, 3Institute for Evidence-Based Medicine in Old Age (IEMO), Leiden, The Netherlands

P563: Thiopurine adverse events in patients with inflammatory bowel disease in the UK: inflammatory bowel disease BioResource cohort

ECCO '19 Copenhagen

Year: 2019
Authors:

Y. Y. Hong*1, D. A. Withanachchi1, S. P. Aslam1, Y. Khalid1, R. Shawky1, M. Parkes1

1Gastroenterology Department, Addenbrooke's Hospital, Cambridge, UK

P564: Significant reduction of admission time at the IBD infusion unit by an e-health pre-admission assessment and order system for intravenous therapy

ECCO '19 Copenhagen

Year: 2019
Authors:

E. Hoefkens*1, L. Pouillon1, V. Verheyen2, M. Bronswijk1, A. Van Olmen1, S. Van Dessel3, N. Siborgs4, P. Bossuyt1,5

1Imelda general hospital, Department of gastroenterology, Bonheiden, Belgium, 2Imelda general hospital, Central hospital pharmacy, Bonheiden, Belgium, 3Imelda general hospital, IBD infusion unit, Bonheiden, Belgium, 4Imelda general hospital, IT department, Bonheiden, Belgium, 5University Hospitals Leuven, Catholic University of Leuven, Department of gastroenterology and hepatology, Leuven, Belgium

P565: Infliximab therapy intensification upon loss of response: what should be the cut-off for trough levels?

ECCO '19 Copenhagen

Year: 2019
Authors:

B. Ungar*1, Z. Ben-Shatach1, G. Ben-Haim1, M. Yavzori1, O. Picard1, E. Fudim1, U. Kopylov1, É. Del Tedesco2, P. Veyrard2, P. Stephane2, R. Eliaklim1, S. Ben-Horin1, X. Roblin2

1Gastroenterology Sheba Medical Center, Ramat Gan, Israel, 2Gastroenterology unit, University hospital of Saint Etienne, Saint-Priest-en-Jarez, France

P566: The cost for IBD care during the first 5 years after diagnosis

ECCO '19 Copenhagen

Year: 2019
Authors:

D. Sjöberg*1, U. Karlbom2, M. Thörn3, D. Fawunmi4, A. Rönnblom3

1Centre of Clinical Research, Falun, Sweden, 2Uppsala University Hospital, Department of Surgical Sciences, Uppsala, Sweden, 3Uppsala University Hospital, Department of Gastroenterology, Uppsala, Sweden, 4Mälarsjukhuset, Medical clinic, Eskilstuna, Sweden

P567: Could an escalation of therapy or intervention (ETI) calculator be used to triage appointments for patients with ulcerative colitis?

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Walsh*1, L. Matini1, R. Kantschuster1, M. Lepetyukh1, R. Nedescu1, J. Wilson1, O. Brain1, R. Palmer1, S. Keshav1, S. Travis1

1John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, UK

P568: Bowel ultrasonography is useful to evaluate disease activity in ulcerative colitis patients

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Takahashi*1, Y. Hirano1, K. Izumikawa1, H. Colvin1, M. Colvin1, T. Kagawa1, Y. Aoyama1, M. Matsueda1, Y. Kawai1, K. Okamoto1, I. Sakakihara1, K. Yamamoto1, S. Tanaka1, M. Matsuura1, S. Ishikawa1, M. Wato1, T. Hasui1, T. Inaba1

1Kagawa Prefectural Central Hospital, Department of Gastroenterological Surgery, Takamatsu, Japan

P569: A national, retrospective, observational study on the use of 5-aminosalicylates (5-ASA) in Crohn’s disease (CD)

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Hart1, S. C. Ng2, S. Ghosh3, J. Watkins4,5, J. Fullarton6, K. Paridaens*7

1St Mark's Hospital, Harrow, UK, 2The Chinese University of Hong Kong, Department of Medicine and Therapeutics, Hong Kong, Hong Kong, 3University of Birmingham, Birmingham, UK, 4Public Health Wales, Cardiff, UK, 5University of Cardiff, Cardiff, UK, 6Strategen Limited, Basingstoke, UK, 7Ferring International Center, St-Prex, Switzerland

P570: Kock pouches in the 21st century: a descriptive study of short-term (30-day) outcomes in a national cohort of 177 patients

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Shawki1, S. Steele1, J. Lipman1, C. H. A. Lee1, L. Stocchi1, T. Hull1, E. Gorgun1, S. Holubar*1

1Cleveland Clinic, Colon and Rectal Surgery, Cleveland, USA

P571: Effectiveness and safety of Ustekinumab for induction of remission in patients with Crohn's disease: a multi-centre Israeli study

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Bar-Gil Shitrit1, M. Siterman2, M. Waterman3, A. Hirsh4, T. Khoury5, D. Schwartz6, E. Zittan7, J. Adler8, B. Koslowsky1, I. Avni-Biron2, Y. Chowers3, Y. Ron4, E. Israeli5, B. Ungar8, H. Yanai2, N. Maharshak4, S. Ben-Horin8, A. Ben-Ya'acov1, R. Eliakim8, I. Dotan2, E. Goldin1, U. Kopylov8

1Shaare Zedek Medical Center, affiliated with the Faculty of Medicine, Hebrew University, Jerusalem, Israel, Digestive Diseases Institute, Jerusalem, Israel, 2Rabin Medical Center, Affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Division of Gastroenterology, Petah Tikwa, Israel, 3Rambam Health Care Campus, Affiliated with the Bruce Rappoport Faculty of Medicine, Technion, Haifa, Israel, Department of Gastroenterology, Haifa, Israel, 4Tel Aviv Sourasky Medical Center, Affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Department of Gastroenterology and Liver Diseases, Tel Aviv, Israel, 5Hebrew University Hadassah Medical Center, Institute of Gastroenterology, Jerusalem, Israel, 6Soroka Medical Center, Affiliated with the Faculty of Medicine, Beer Sheba University, Beer Sheba, Israel, Department of Gastroenterology, Beer Sheva, Israel, 7Haemek Medical Center, Affiliated with the Bruce Rappoport Faculty of Medicine, Technion, Haifa, Israel, Department of Gastroenterology, Afula, Israel, 8Sheba Medical Center, Tel Hashomer, Affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Department of Gastroenterology, Tel Hashomer, Israel

P572: Half of children with acute severe colitis have predominant single faecal bacterial species, mostly Escherichia coli: Microbiome results from the PRASCO trial

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Bishai1, G. Abitbol2, G. Focht2, M. Schirmer1, D. Marcus2, B. Yerushalmi3, M. Aloi4, A. M. Griffiths5, L. Albenberg1, K-L. Kolho6, S. Cohen7, A. Assa8, A. Levine9, H. Vlamakis1, R. Xavier1, D. Turner*2

1The Broad Institute of MIT and Harvard, Center for Computational and Integrative Biology, Boston, USA, 2Shaare Zedek Medical Center, The Juliet Keidan Institute of Paediatric Gastroenterology and Nutrition, Jerusalem, Israel, 3Faculty of Health Sciences, Ben-Gurion University of the Negev, Department of Gastroenterology and Hepatology, Beer Sheva, Israel, 4Sapienza University of Rome, Rome, Italy, 5The Hospital for Sick Children (SickKids), Toronto, Canada, 6Hospital for Children and Adolescents, Children′s Hospital, Helsinki University, Helsinki, Finland, 7Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 8Schneider Children's Medical Center, Petach Tiqua, Israel, 9Wolfson Medical Center, Holon, Israel