¹McGill University Health Centre, Department of Gastroenterology, Montreal, Canada, ²Mayo Clinic, Division of Gastroenterology and Hepatology, Rochester, USA, ³Prometheus Laboratories Inc., San Diego, USA, ⁴University of California San Diego, Division of Gastroenterology, La Jolla, USA

¹University of Szeged, First Department of Internal Medicine, Szeged, Hungary, ²Military Hospital - State Health Centre, Budapest, Hungary, ³Semmelweis University, Second Department of Internal Medicine, Budapest, Hungary, ⁴University of Debrecen, Department of Gastroenterology, Department of Medicine, Clinical Centre, Debrecen, Hungary, ⁵Péterfi Sándor Utcai Hospital Centre, Budapest, Hungary, ⁶Tolna County Teaching Hospital, Department of Gastroenterology, Szekszárd, Hungary, ⁷Markusovszky Hospital, Department of Medicine and Gastroenterology, Szombathely, Hungary, ⁸University of Debrecen, Institute of Medicine, Department of Gastroenterology, Debrecen, Hungary, ⁹University of Debrecen, Division of Gastroenterology, Department of Internal Medicine, Debrecen, Hungary, ¹⁰Pándy Kálmán Hospital of Békés County, Gyula, Hungary, ¹¹Department of Medicine, Csolnoky F. Province Hospital, Veszprém, Hungary, ¹²Semmelweis University, First Department of Internal Medicine, Budapest, Hungary, ¹³Unversity of Pécs, Division of Gastroenterology, First Department of Medicine, Pécs, Hungary, ¹⁴University of Pécs, Second Department of Internal Medicine, Pécs, Hungary, ¹⁶Semmelweis University, First Deparment of Surgery, Budapest, Hungary, ¹⁷Buda Hospital of the Hospitaller Order of Saint John of God, Budapest, Hungary, ¹⁸University of Pécs, First Department of Internal Medicine, Pécs, Hungary

¹IBD Unit, Villa Sofia-Cervello Hospital, Palermo, Italy, ²Gastroenterology and Endoscopy Unit, ARNAS Civico-Di Cristina-Benfratelli Hospital, Palermo, Italy, ³Department of Gastroenterology, Federico II University, Naples, Italy, ⁴Gastroenterology Unit, San Camillo Forlanini, Rome, Italy, ⁵Department of Gastroenterology, San Filippo Neri Hospital, Rome, Italy, ⁶Department of Gastroenterology, IRCCS, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo (FG), Italy, ⁷Department of Gastroenterology, Sapienza University, Rome, Italy, ⁸Department of Gastroenterology, Tor Vergata University, Rome, Italy, ⁹Department of Gastroenterology, Palermo University, Palermo, Italy, ¹⁰Gastroenterology Unit, Villa Sofia-Cervello Hospital, Palermo, Italy, ¹¹Internal Medicine, Villa Sofia-Cervello Hospital, Palermo, Italy

¹St Vincent's Hospital, Gastroenterology, Melbourne, Australia

¹University of California - San Diego, La Jolla, USA, ²Nancy University Hospital, Nancy, France, ³IQVIA, Cambridge, USA, ⁴IQVIA, London, UK, ⁵Takeda Pharmaceuticals International AG, Zurich, Switzerland, ⁶Takeda Pharmaceuticals USA, Inc., Deerfield, USA, ⁷Takeda International – UK Branch, London, UK, ⁸Takeda Pharmaceuticals International, Deerfield, USA, ⁹Western University, London, ON, Canada

¹Shaare Zedek Medical Center, The Juliet Keidan Institute of Paediatric Gastroenterology and Nutrition, Jerusalem, Israel, ²Children's Hospital University Medical Centre, Department of Gastroenterology, Hepatology and Nutrition, Ljubljana, Slovenia, ³Assaf Harofeh Medical Center, The Kamila Gonczarowski Institute for Gastroenterology and Liver Diseases, Beer Yaakov, Israel, ⁴Schneider Children's Medical Center, The Institute of Gastroenterology, Nutrition and Liver Diseases, Petah Tikva, Israel, ⁵Our Lady's Children's Hospital, Crumlin, National Centre for Paediatric Gastroenterology, Dublin, Ireland, ⁶Tel Aviv Sourasky Medical Center, ‘Dana-Dwek’ Children's Hospital, Pediatric Gastroenterology, Liver and Nutrition Unit, Tel Aviv, Israel, ⁷Wolfson Medical Center, Pediatric Gastroenterology and Nutrition Unit, Holon, Israel, ⁸Cohen Children's Medical Center of NY, Division of Pediatric Gastroenterology and Nutrition, New York, USA, ⁹Hvidovre University Hospital, Department of Paediatrics, Hvidovre, Denmark

¹Bordeaux University Hospital, Gastroenterology and nutrition, Bordeaux, France

¹LUMC, Gastroenterology-Hepatology, Leiden, The Netherlands, ²LUMC, Department of Clinical Pharmacy and Toxicology, LEIDEN, The Netherlands

¹Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, OU IBD Presidio Columbus, Rome, Italy, ²A.O. Ordine Mauriziano, Gastroenterology Unit, Turin, Italy, ³Humanitas Research Hospital, IBD Center, Department of Gastroenterology, Rozzano, Italy, ⁴University of Padua, Gastroenterology Unit, Department Surgery, Oncology and Gastroenterology, Padua, Italy, ⁵General and Specialistic Medicine/Gastroenterology, Città della Salute e della Scienza di Torino, Turin, Italy, ⁶University of Rome Tor Vergata, Department of Systems Medicine, Gastroenterology, Rome, Italy, ⁷Federico II University, Gastroenterology, Naples, Italy, ⁸Gastroenterologia ed Endoscopia Digestiva Aziendale USL Umbria1, Perugia, Italy, ⁹Gastroenterology and Hepatology Section, DiBiMis, Palermo, Italy, ¹⁰University of Genoa, Gastrointestinal Unit, Department of Internal Medicine, Genoa, Italy, ¹¹Department of Pathophysiology and Transplantation, University of Milan and Gastroenterology and Endoscopy Unit, IRCCS Cà Granda, IRCCS Policlinico Hospital, Milan, Italy, ¹²San Filippo Neri Hospital, IBD Unit, Rome, Italy, ¹³Department of New Technologies and Translational Research in Medicine and Surgery, Pisa, Italy, ¹⁴Luigi Sacco University Hospital, Gastroenterology and IBD Unit, Milan, Italy, ¹⁵San Nicola Pellegrino Hospital, Gastroenterology Unit, Trani, Italy, ¹⁶‘Brotzu’ Hospital, Division of Gastroenterology, Cagliari, Italy, ¹⁷University of Modena and Reggio Emilia, Department of Internal Medicine, Gastroenterology Unit, Modena, Italy, ¹⁸Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Department of Dermatology, Rome, Italy, ¹⁹Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Division of Rheumatology, Rome, Italy, ²⁰OU IBD Presidio Columbus, Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Rome, Italy

¹University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ²KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium, ³University Hospitals Leuven, Department of Abdominal surgery, Leuven, Belgium

¹Sapienza University, Internal Medicine and Medical Specialties, Rome, Italy, ²Sandro Pertini Hospital, Unit of Gastroenterology and Digestive Endoscopy, Rome, Italy, ³’Cristo Re’ Hospital, Internal Medicine, Rome, Italy

¹Hôpital Archet 2, Alpes-Maritimes, Nice, France

¹Inflammatory Bowel Disease Unit, A.O.U. Policlinico ‘G. Martino’, Messina, Italy, ²University of Messina, Department of Economics, Unit of Statistical and Mathematical Sciences, messina, Italy, ³Inflammatory bowel disease Unit, A.O.O.R. ‘Villa Sofia-Cervello’, Palermo, Italy, ⁴Gastroenterology and Hepatology Unit, A.O.U. Policlinico ‘G. Giaccone’, Palermo, Italy, ⁵Gastroenterology Unit, A.R.N.A.S. ‘Garibaldi’, Catania, Italy, ⁶Inflammatory Bowel Disease Unit, A.O. ‘Cannizzaro’, Catania, Italy, ⁷Internal Medicine Unit, A.O.U. Policlinico ‘Vittorio Emanuele’, Catania, Italy, ⁸Gastroenterology and Endoscopy Unit, A.R.N.A.S. ‘Civico Di Cristina Benfratelli’, Palermo, Italy, ⁹Gastroenterology Unit, A.O. ‘Santa Marta e S. Venera’, Acireale (CT), Italy, ¹⁰Internal Medicine Unit, A.O. ‘Giovanni Paolo II’, Sciacca (AG), Italy, ¹¹Gastroenterology Unit, A.O. ‘Guzzardi’, Vittoria (RG), Italy, ¹²Gastroenterology Unit, A.O.O.R. ‘Papardo Piemonte’, Messina, Italy, ¹³Gastroenterology Unit, A.O.O.R. ‘S. Elia- M. Raimondi’, Caltanissetta, Italy, ¹⁵Inflammatory Bowel Disease Unit, A.O.O.R. ‘Villa Sofia-Cervello’, Messina, Italy, ¹⁶University of Messina, Department of Clinical and Experimental Medicine, Messina, Italy

¹Progenika Biopharma, S.A, A Grifols company, Derio, Spain, ²Unidad de Enfermedad Inflamatoria Intestinal Hospital Universitario La Paz, Madrid, Spain, ³Unidad de Inmunología, Madrid, Spain

¹Amsterdam UMC, Tytgat Institute for Liver and Intestinal Research, Amsterdam, The Netherlands, ²Amsterdam UMC, Department of Surgery, Amsterdam, The Netherlands, ³Flevoziekenhuis, Department of Surgery, Almere, The Netherlands, ⁴Amsterdam UMC, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands

¹University of California San Diego, La Jolla, CA, USA, ²Takeda Pharmaceuticals U.S.A., Inc., Deerfield, IL, USA

¹Medical University Varna, Clinic of Hepatogastroenterology, St. Marina University Hospital, Vаrna, Bulgaria, ²Medical University Varna, Department of General Medicine and Clinical Laboratory, Varna, Bulgaria

¹Guy's and St. Thomas' Hospitals NHS Foundation Trust, Gastroenterology, London, UK

¹HaEmek Medical Center, Ellen and Pinchas Mamber Institute of Gastroenterology and Liver Diseases and the Center for IBD, Afula, Israel, ²Technion-Israel Institute of Technology, Rappaport Faculty of Medicine, Haifa, Israel, ³HaEmek Medical Center, Department of Surgery, Afula, Israel

¹Shaare-Zedek Medical Center, Digestive Diseases Institute, Jerusalem, Israel