¹Fondazione Policlinico Gemelli IRCCS, Gastroenterology, Rome, Italy, ²Mauriziano Hospital, Gastroenterology Unit, Torino, Italy, ³Padua University, Gastroenterology Unit, Padua, Italy, ⁴Città della Scienza e della Salute, Gastroenterology Unit, Torino, Italy, ⁵Bari University, Gastroenterology Unit, Bari, Italy, ⁶Spedali Civili, Internal Medicine, Brescia, Italy, ⁷IRCCS De Bellis, Gastroenterology Unit, Castellana Grotte, Italy, ⁸S. Camillo-Forlanini Hospital, Gastroenterology Unit, Rome, Italy, ⁹Genova University Hospital, Gastroenterology Unit, Genova, Italy, ¹⁰Rho Hospital, Gastroenterology Unit, Rho, Italy, ¹¹Cannizzaro Hospital, Gastroenterology, Catania, Italy, ¹²S. Croce and Carle Hospital, Gastroenterology Unit, Cuneo, Italy

¹R-Biopharm AG, Clinical Diagnostics, Darmstadt, Germany, ²Erasmus MC, Gastroenterology and Hepatology Diagnostic Laboratory, Rotterdam, The Netherlands

¹Erasmus MC-Sophia Children’s Hospital, Paediatric Gastroenterology, Rotterdam, The Netherlands, ²Erasmus MC, Department of Gastroenterology, Rotterdam, The Netherlands

¹Hospital Universitario La Paz, Servicio de Ap. Digestivo, Madrid, Spain

¹Oslo University Hospital, Department of Gastroenterology, Oslo, Norway, ²University of Oslo, Institute of Clinical Medicine, Oslo, Norway, ³University of Oslo, Institute of Health and Society, Oslo, Norway

¹IRCCS Sacro Cuore Don Calabria, IBD Unit, Negrar, Italy, ²IRCCS Sacro Cuore Don Calabria, Division of Medical Oncology, Negrar, Italy, ³IRCCS Sacro Cuore Don Calabria, Department of Pathology, Negrar, Italy, ⁴Mount Sinai Hospital University of Toronto, Department of Pathology and Laboratory Medicine, Toronto, Canada

¹Rambam Health Care Campus, Department of Gastroenterology, Haifa, Israel, ²Sheba Medical Center, Department of Gastroenterology, Ramat Gan, Israel, ³Tel Aviv University, The Sackler School of Medicine, Tel Aviv, Israel, ⁴IDF Medical Corps, Tel Hashomer, Israel, ⁵Schneider Children's Medical Center, Institute of Gastroenterology, Nutrition and Liver Disease, Petach Tikva, Israel

¹Mauriziano Hospital, Gastroenterology Unit, Torino, Italy, ²Istituto Cinico Locorotondo, Gastroenterology and Endoscopy, Palermo, Italy, ³Mauriziano Hospital, Surgery, Turin, Italy, ⁴ASL CN1 Savigliano Hospital, Surgery, Savigliano, Italy

¹Yokkaichi Hazu Medical Centre, IBD Centre, Yokkaichi, Japan, ²Hamamatsu South Hospital, Center for Gastroenterology and Inflammatory Bowel Disease Research, Hamamastu, Japan, ³Hamamatsu University School of Medicine, First Department of Medicine, Hamamatsu, Japan, ⁴Hamamatsu University School of Medicine, Department of Endoscopic and Photodynamic Medicine, Hamamatsu, Japan

¹Hospital Beatriz Ângelo, Loures, Portugal, ²Instituto Gulbenkian de Ciência, Lisboa, Portugal

¹University of Palermo, Gastroenterology Section, DiBiMis, Palermo, Italy, ²University of Palermo, Internal Medicine and Cardioangiology, DiBiMis, Palermo, Italy, ³University of Palermo - Italy, Gastroenterology Section, DiBiMis, Palermo, Italy

¹Queen Elizabeth II Jubilee Hospital, Gastroenterology, Brisbane, Australia, ²The University Of Queensland, Faculty of Medicine, Brisbane, Australia, ³James Cook University, College of Medicine and Dentistry, Townsville, Australia, ⁴Mater Hospital Brisbane, Gastroenterology, Brisbane, Australia, ⁵Concord Repatriation General Hospital,, Sydney, Australia, ⁶University of New South Wales, Faculty of Medicine, Sydney, Australia, ⁷Macquarie University, Faculty of Medicine and Health Sciences, Sydney, Australia, ⁸Liverpool Hospital, Gastroenterology, Sydney, Australia, ⁹Eastern Health, Gastroenterology, Melbourne, Australia, ¹⁰Monash University, Faculty of Medicine, Nursing and Health Sciences, Melbourne, Australia, ¹¹Fiona Stanley Hospital, Gastroenterology, Perth, Australia, ¹²University of Western Australia,, Faculty of Health and Medical Sciences, Perth, Australia, ¹³St Vincent’s Hospital, Gastroenterology, Melbourne, Australia, ¹⁴University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences, Melbourne, Australia, ¹⁵The Alfred, Gastroenterology, Melbourne, Australia, ¹⁶Royal Adelaide Hospital, Gastroenterology, Adelaide, Australia, ¹⁷University of Adelaide, Faculty of Health and Medical Sciences, Adelaide, Australia, ¹⁸Christchurch Hospital, Gastroenterology, Christchurch, New Zealand, ¹⁹University of Otago, Department of Medicine, Christchurch, New Zealand, ²⁰St Vincent’s Hospital, Gastroenterology, Sydney, Australia, ²¹QIMR Berghofer, Brisbane, Australia, ²²Mater Research Institute - UQ, Brisbane, Australia

¹Tan Tock Seng Hospital, Gastroenterology and Hepatology, Singapore, Singapore

¹Countess of Chester Hospital, Chester, UK

¹Hospital Universitario de Canarias, Gastroenterology, Santa Cruz de Tenerife, Spain, ²Hospital Universitario La Princesa. IIS-IP, CIBEREHD, Gastroenterology, Madrid, Spain, ³Hospital Universitario La Fe, Gastroenterology, Valencia, Spain, ⁴Hospital Universitario de Canarias, Statistics, Santa Cruz de Tenerife, Spain

¹Hutt Valley Hospital, Gastroenterology Department, Lower Hutt, New Zealand, ²University of Otago, Department of Medicine, Wellington, New Zealand

¹Takeda Development Center Americas Inc., Cambridge, USA, ²Metrum Research Group, Tariffville, USA, ³Aucuba Sciences, Ltd.,, Canterbury, Kent, UK, ⁴Robarts Clinical Trials, Robarts Research Institute, University of Western Ontario, London, ON, Canada, ⁵University of California San Diego, La Jolla, USA, ⁶Amsterdam University Medical Centers, Amsterdam, The Netherlands

¹University Hospitals Leuven, Catholic University of Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ²Imelda General Hospital, Department of Gastroenterology, Bonheiden, Belgium, ³Imelda General Hospital, Department of Laboratory Medicine, Bonheiden, Belgium, ⁴Imelda General Hospital, Central Hospital Pharmacy, Bonheiden, Belgium

¹Medical University of Vienna, Vienna, Austria, ²Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA, ³St Vincent's University Hospital, University College Dublin, Dublin, Ireland, ⁴Pfizer Inc., Collegeville, PA, USA, ⁵Pfizer Inc., New York, NY, USA

¹University Hospital Münster, Department of Medicine B, Gastroenterology and Hepatology, Münster, Germany, ²Cleveland Clinic Foundation, Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland, USA, ³University of Alberta, Division of Gastroenterology, Edmonton, Canada, ⁴Osaka City University Graduate School of Medicine, Department of Gastroenterology, Osaka, Japan, ⁵Fukuoka University Chikushi Hospital, Chikushino, Inflammatory Bowel Disease Center, Fukuoka, Japan, ⁶Fujita Health University School of Medicine, Department of Gastroenterology, Toyoake city, Japan, ⁷Cleveland Clinic Foundation, Department of Gastroenterology, Hepatology and Nutrition, Digestive Disease Institute, Cleveland, USA, ⁸Cleveland Clinic Foundation, Department of Pathobiology, Lerner Research Institute, Cleveland, USA