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P452: Impact of implementing a rapid access clinic in a high-volume inflammatory bowel disease centre: accessibility, resource utilisation and outcomes

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Reinglas*1, S. Nene1, L. Gonczi2, Z. Kurti2, S. Restellini3, R. Kohen1, W. Afif1, T. Bessissow1, G. Wild1, E. Seidman1, A. Bitton1, P. Lakatos1

1McGill University Health Center, Division of Gastroenterology, Montreal, Canada, 2Semmelweis University, First Department of Internal Medicine, Budapest, Hungary, 3Geneva’s University Hospitals and University of Geneva, Division of Gastroenterology and Hepatology, Geneva, Switzerland

P453: Golimumab in real-world practice in patients with ulcerative colitis: 2-year interim results from a non-interventional trial in Germany

ECCO '19 Copenhagen

Year: 2019
Authors:

N. Teich1, H. Gruemmer2, E. Joergensen3, T. Liceni4, W. Holtkamp-Endemann5, F. Cornillie6, S. Hohenberger7, T. Fischer*7

1Internistische Gemeinschaftspraxis für Verdauungs- und Stoffwechselkrankheiten Leipzig und Schkeuditz, Leipzig, Germany, 2Praxis Gruemmer, Potsdam, Germany, 3Magen Darm Zentrum, Remscheid, Germany, 4MVZ für Gastroenterologie am Bayerischen Platz, Berlin, Germany, 5Gastroenterologische Gemeinschaftspraxis am Germania-Campus, Muenster, Germany, 6MSD Merck Sharp and Dohme AG, Global Medical Affairs, Kriens, Switzerland, 7MSD Sharp and Dohme GmbH, Medical Affairs, Haar, Germany

P454: Prediction of endoscopic activity in patients with Crohn’s disease: systematic review and external validation of published prediction models

ECCO '19 Copenhagen

Year: 2019
Authors:

E. C. Brand*1,2, S. G. Elias3, I. M. Minderhoud4, J. J. van der Veen1, F. Baert5, D. Laharie6, P. Bossuyt7, Y. Bouhnik8, A. Buisson9, G. Lambrecht10, E. Louis11, B. Pariente12, M. J. Pierik13, C. J. van der Woude14, G. R. D'Haens15, S. Vermeire16, B. Oldenburg1

1University Medical Centre Utrecht, Department of Gastroenterology and Hepatology, Utrecht, The Netherlands, 2University Medical Centre Utrecht, Laboratory for Translational Immunology, Utrecht, The Netherlands, 3University Medical Centre Utrecht, Julius Centre for Health Sciences and Primary Care, Utrecht, The Netherlands, 4Tergooi hospitals, Department of Gastroenterology and Hepatology, Blaricum/Hilversum, The Netherlands, 5AZ Delta, Department of Gastroenterology, Roeselare, Belgium, 6Hôpital Haut-Lévêque, Service d'Hépato-gastroentérologie et Oncologie Digestive, Bordeaux, France, 7Imelda General Hospital, IBD Clinic, Bonheiden, Belgium, 8Beaujon Hospital, APHP, Paris Diderot University, Department of Gastroenterology, Clichy, France, 9Estaing University Hospital, Department of Gastroenterology, Clermont-Ferrand, France, 10AZ Damiaan, Department of Gastroenterology, Oostende, Belgium, 11Liège University Hospital CHU, Department of Gastroenterology, Liège, Belgium, 12Huriez Hospital, Lille 2 University, Department of Gastroenterology, Lille, France, 13Maastricht University Medical Centre, Department of Gastroenterology and Hepatology, Maastricht, The Netherlands, 14Erasmus Medical Centre, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands, 15Amsterdam UMC, University of Amsterdam, Department of Gastroenterology, Amsterdam, The Netherlands, 16University Hospitals Leuven, Department of Gastroenterology and Hepathology, Leuven, Belgium

P455: Evaluation of the optic nerve function in patients with ulcerative colitis and Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Skamnelos*1, A. Kavvadias1, P. Zafeiropoulos2, K. Katsanos1, I. Asproudis2, D. Christodoulou1

1University Hospital of Ioannina, Division of Gastroenterology, Ioannnina, Greece, 2University Hospital of Ioannina, Universital Eye Clinic, Ioannnina, Greece

P456: Quality of life is associated with wearable-based physical activity in patients with inflammatory bowel disease: a prospective, observational study

ECCO '19 Copenhagen

Year: 2019
Authors:

M. Wiestler*1, F. Kockelmann1, M. Kück2, A. Kerling2, U. Tegtbur2, M. P. Manns1, M. Attaran-Bandarabadi1, O. Bachmann1

1Hannover Medical School (MHH), Gastroenterology, Hepatology and Endocrinology, Hannover, Germany, 2Hannover Medical School (MHH), Institute for Sports Medicine, Hannover, Germany

P457: Influence of concomitant immunomodulators during maintenance therapy with Adalimumab in inflammatory bowel disease: looking for the ideal patient to use monotherapy

ECCO '19 Copenhagen

Year: 2019
Authors:

G. Bastida*1, V. Bosó2, M. Aguas1, S. Bejar1, A. Garrido1, M. Iborra1, J. del Hoyo1, L. Tortosa1, D. Muñoz1, R. Marqués2, J. L. Poveda2, P. Nos1

1Hospital Universitario y Politécnico La Fe, Gastroenterology, Valencia, Spain, 2Hospital Universitario y Politécnico La Fe, Pharmacy, Valencia, Spain

P458: Effect of cognitive behavioural therapy on clinical disease course in adolescents and young adults with inflammatory bowel disease and subclinical anxiety and/or depression: results of a randomised trial

ECCO '19 Copenhagen

Year: 2019
Authors:

G. van den Brink1, L. Stapersma2, A. S. Bom1, D. Rizopolous3, J. van der Woude4, R. Stuyt5, D. Hendriks6, J. van der Burg6, R. Beukers7, T. Korpershoek7, S. Theuns7, E. Utens2,8,9, J. Escher*1

1Erasmus MC-Sophia Children’s Hospital, Paediatric Gastroenterology, Rotterdam, The Netherlands, 2Erasmus MC-Sophia Children’s Hospital, Department of Child and Adolescent Psychiatry/Psychology, Rotterdam, The Netherlands, 3Erasmus MC, Department of Biostatistics, Rotterdam, The Netherlands, 4Erasmus MC, Department of Gastroenterology, Rotterdam, The Netherlands, 5Haga Hospital, Department of Gastroenterology, The Hague, The Netherlands, 6Juliana Children’s Hospital, Department of Paediatrics, The Hague, The Netherlands, 7Albert Schweitzer Hospital, Department of Paediatrics, Dordrecht, The Netherlands, 8University of Amsterdam, Research Institute of Child Development and Education, Amsterdam, The Netherlands, 9Academic Center for Child Psychiatry the Bascule, Department of Child and Adolescent Psychiatry, Amsterdam, The Netherlands

P459: Vedolizumab for the treatment of chronic pouchitis: the Edinburgh experience

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Cesano*1,2, G. R. Jones2, P. W. Jenkinson2, A. G. Shand2, C. W. Lees2, I. D. Arnott2, N. Plevris2

1University of Pavia, Pavia, Italy, 2The Edinburgh IBD Unit, Western General Hospital, Edinburgh, UK

P460: Efficacy of ustekinumab in patients with anti-TNF refractory Crohn’s disease: data from a real-world study in Brazil

ECCO '19 Copenhagen

Year: 2019
Authors:

R. S. Parra*1, M. R. Feitosa1, O. Féres1, J. J. Ribeiro da Rocha1, J. M. F. Chebli2, L. Chebli2, E. R. Bertges2, T. N. F. Gomes3, O. Ambrogini Jr3, A. J. T. Alves Junior4, M. Lubini5

1Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil, Surgery and Anatomy, Ribeirão Preto, SP, Brazil, 2Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil, 3Universidade Federal de São Paulo (Unifesp), São Paulo, Brazil, 4Clínica Reis Neto, Campinas, SP, Brazil, 5Universidade de Passo Fundo - RG, Passo Fundo / RG, Brazil

P461: Endoscopic features for loss of response in patients with Crohn’s disease who were treated with infliximab by top-down strategy

ECCO '19 Copenhagen

Year: 2019
Authors:

T. Miyazaki*1, K. Watanabe2, K. Kojima1, R. Koshiba1, K. Fujimoto1, T. Sato2, M. Kawai1, K. Kamikozuru1, T. Takagawa1, Y. Yokoyama2, N. Hida1, S. Nakamura1

1Hyogo College of Medicine, Inflammatory Bowel Disease, Nishinomiya, Japan, 2Hyogo College of Medicine, Intestinal Inflammation Research, Nishinomiya, Japan

P462: Dietary restrictions on inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

C. Macedo*1, F. Portela1, A. M. Ferreira1, S. Lopes1, S. Mendes1, M. Ferreira1, L. Tomé1

1Coimbra Hospital and University Centre, Gastroenterology, Coimbra, Portugal

P463: Factors to determine prognosis of intestinal cancer associated with Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

M. Shinozaki*1, R. Takahashi1

1The University of Tokyo, Surgery, Tokyo, Japan

P464: Study of the usual aetiologies of methotrexate and azathioprine discontinuation in inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Skamnelos*1, K. Katsanos1, D. Christodoulou1

1University Hospital of Ioannina, Division of Gastroenterology, Ioannnina, Greece

P465: UC trial designed more than 5 years ago in the light of the EMA guideline on the development of new medicinal products for the treatment of ulcerative colitis

ECCO '19 Copenhagen

Year: 2019
Authors:

R. Laoun*1, R. Hofmann2

1Tillotts Pharma AG, Medical Affairs, Rheinfelden, Switzerland, 2Tillotts Pharma, Medical Affairs, Rheinfelden, Switzerland

P466: Tofacitinib for the treatment of ulcerative colitis: Up to 5.4 years of safety data from global clinical trials

ECCO '19 Copenhagen

Year: 2019
Authors:

W. J. Sandborn1, J. Panés*2, R. Panaccione3, G. R. D’Haens4, B. E. Sands5, C. Su6, M. Moscariello6, T. V. Jones6, R. D. Pedersen6, G. S. Friedman6, N. Lawendy6, G. Chan6

1University of California, San Diego, Division of Gastroenterology, La Jolla, CA, USA, 2Hospital Clínic de Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain, 3University of Calgary, Calgary, AB, Canada, 4Academic Medical Centre, Department of Gastroenterology, Amsterdam, The Netherlands, 5Icahn School of Medicine at Mount Sinai, Dr. Henry D. Janowitz Division of Gastroenterology, New York, NY, USA, 6Pfizer Inc., Collegeville, PA, USA

P467: Circulating CD8 α4β7+ and CD8b7+ memory T cells as early biomarkers of clinical response to vedolizumab in ulcerative colitis

ECCO '19 Copenhagen

Year: 2019
Authors:

M. Gonzalez-Vivo1, M. K. Lund Tiirikainen2, C. de Jesús Gi2, E. Ruiz-Romeu2, L. Sans2, L. Canillas1, M. Andreu1, L. F. Santamaria-Babí2, L. Marquez*1

1Hospital del Mar, Gastroenterology, Barcelona, Spain, 2Parc Científic de Barcelona (PCB/UB)., Traslational Immunology, Barcelona, Spain

P468: Long-term function after transanal vs. transabdominal ileal pouch-anal anastomosis for ulcerative colitis: a multi-centre cohort study

ECCO '19 Copenhagen

Year: 2019
Authors:

P. Chandrasinghe1, M. Carvello2, K. Wasmann3, P. Tanis3, J. Warusavitarne5, A. Spinelli*2, W. Bemelman3

1Imperial College, London, UK, 2Humanitas Research Hospital, Milan, Italy, 3Academic Medical Center, Amsterdam, The Netherlands, 5St Mark's Hospital, Harrow, UK

P469: Effectiveness of dose optimisation by pre-genotyping NUDT 15 R139C on reducing thiopurine-induced leucopoenia in Chinese patients with Crohn’s disease: a randomised controlled trial

ECCO '19 Copenhagen

Year: 2019
Authors:

K. Chao*1, L. Lin1, Y. Huang2, C. Zhang3, J. Huang1, Q. Cao2, X. Gao1, K. Chao1

1The Sixth Affiliated Hospital, Sun Yat-sen University, Department of Gastroenterology, Guangzhou, China, 2Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Department of Gastroenterology, Hangzhou, China, 3School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China

P470: DUBLIN (Degree of Ulcerative colitis Burden of Luminal INflammation) score, a simple method to quantify inflammatory burden in ulcerative colitis

ECCO '19 Copenhagen

Year: 2019
Authors:

C. R. Rowan*1, G. Cullen1, H. E. Mulcahy1, J. Sheridan1, A. C. Moss2,3, E. J. Ryan1, G. A. Doherty1

1St.Vincent's University Hospital, Center for Colorectal Disease, Dublin, Ireland, 2Beth Israel Deaconess Medical Center, Gastroenterology, Boston, USA, 3Harvard Medical School, Boston, USA

P471: Association of vedolizumab levels with clinical and biochemical markers of inflammation during maintenance therapy in inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

N. Plevris*1, G. R. Jones1, P. W. Jenkinson1, C. S. Chuah1, M. Lyons1, L. M. Merchant1, R. J. Pattenden1, I. D. Arnott1, C. W. Lees1

1Western General Hospital, NHS Lothian, Edinburgh, UK