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P392: Body mass index has no effect on treatment response in Crohn's disease patients with moderate disease activity who receive adalimumab

ECCO '19 Copenhagen

Year: 2019
Authors:

K. Soufleris*1, K. Fasoulas1, N. Kafalis1, G. Lazaraki1, D. Tzilves1

1Theagenion CHT, Gastroenterology Department, Thessaloniki, Greece

P393: Outcome of treat to target strategy in paediatric patients with Crohn’s disease and ulcerative colitis on infliximab

ECCO '19 Copenhagen

Year: 2019
Authors:

D. Yerlioglu*1, L. Cococcioni1, A. ElZein1, S. Sider1, S. Chadokufa1, R. Buckingham1, N. Shah1, A. Ocholi1, O. Borrelli1, F. Kiparissi1

1Great Ormond Street Hospital, Gastroenterology, London, UK

P394: Contribution of the CDEIS in the new therapeutic approach of Crohn's disease

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Sabbek*1, N. Elleuch2, A. Ben Slama2, E. Hammami2, H. Jaziri2, A. Braham2, S. Ajmi2, M. Ksiaa2, A. Jmaa2

1Sahloul Sousse, Gastroenterology, Sousse, Tunisia, 2Sahloul Sousse, Sousse, Tunisia

P395: Postoperative immunosuppressive therapies decrease the risk of second intestinal surgery in patients with Crohn’s disease: a retrospective cohort study

ECCO '19 Copenhagen

Year: 2019
Authors:

Y. Nagata*1,2, M. Esaki3, Y. Fuyuno2, Y. Okamoto2, S. Fujioka2, A. Hirano2, J. Umeno2, T. Torisu2, T. Moriyama2, S. Nakamura1, T. Kitazono2

1Steel Memorial Yawata Hospital, Department of Gastroenterology, Fukuoka, Japan, 2Kyushu University, Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Fukuoka, Japan, 3Saga University Hospital, Department of Endoscopy, Saga, Japan

P396: Monitoring adalimumab compliance using smart sharp bin technology

ECCO '19 Copenhagen

Year: 2019
Authors:

K. Hazel*1, C. Smyth1, O. Kelly1, R. J. Farrell1

1Connolly Hospital, Blanchardstown, Department of Gastroenterology, Dublin, Ireland

P397: Autologous stem cell transplantation in refractory Crohn's disease: evaluation of a modified mobilisation regimen and analyses of the cost-effectiveness

ECCO '19 Copenhagen

Year: 2019
Authors:

N. Mahmmod*1, S. Mahmmod2, M. Severs2, H. Koene3, F. van Wijk4, B. Oldenburg2, H. Fidder2

1Sint Antonius Teaching Hospital, Gastroenterology, Nieuwegein, The Netherlands, 2University Medical Center Utrecht, Gastroenterology, Utrecht, The Netherlands, 3Sint Antonius Teaching Hospital, Hematology, Nieuwegein, The Netherlands, 4University Medical Center Utrecht, Pediatrics, Laboratory of Translational Immunology, Utrecht, The Netherlands

P398: Leptin controls immune cell composition and activity in acquired generalised lipodystrophy with combined Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

J. F. Ziegler*1, C. Böttcher2, H. Wu1, R. Glauben1, B. Siegmund1, C. Weidinger1,3

1Charité - Universitätsmedizin Berlin, Department of Gastroenterology, Rheumatology and Infectious Disease, Campus Benjamin Franklin, Berlin, Germany, 2Charité – Universitätsmedizin Berlin, Laboratory of Molecular Psychiatry and Department of Neuropsychiatry, DZNE Berlin, Berlin, Germany, 3Berlin Institute of Health, Berlin, Germany

P399: Cost-effectiveness of utilising proactive Infliximab therapeutic drug monitoring for inflammatory bowel disease in routine clinical practice

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Steen*1, M. McCormack2, C. McShane1, M. Healy2, V. Crowley2, U. Kennedy1, O. Hayes1, C. Dunne1, K. Hartery1, S. McKiernan1, F. MacCarthy1, D. Kevans1

1St. James Hospital, Gastroenterology, Dublin, Ireland, 2St. James Hospital, Biochemistry, Dublin, Ireland

P400: Discordance in patient and physician perspectives and priorities in communication and management of ulcerative colitis: results of the European ulcerative colitis narrative survey

ECCO '19 Copenhagen

Year: 2019
Authors:

L. Peyrin-Biroulet1, A. Hart2, C. Kayhan3, A. Armuzzi4, S. Schreiber*5

1Nancy University Hospital, Lorraine University, Vandœuvre-lès-Nancy, France, 2St. Mark’s Hospital, IBD Unit, London, UK, 3Pfizer Inc., Collegeville, PA, USA, 4Presidio Columbus Fondazione Policlinico A. Gemelli IRCCS – Università Cattolica del Sacro Cuore, IBD Unit, Rome, Italy, 5University Hospital Schleswig-Holstein, Department of Internal Medicine, Kiel, Germany

P401: Association between induction vedolizumab drug levels and therapy outcome in inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

J. O'Connell1, M. S. Ismail2, M. McCormack3, P. McDonagh1, R. Argue4, N. Breslin2,5, V. Crowley3, G. Cullen5,6, G. A. Doherty5,6, C. Dunne1,5, K. Hartery1,5, F. MacCarthy5,7, S. McKiernan1,5, H. Mulcahy5,6, A. O'Connor2,5, C. O'Morain8, B. Ryan2,5, J. Sheridan5,6, M. Healy3, D. McNamara2,5, D. Kevans1,5

1St James's Hospital, Department of Gastroenterology, Dublin, Ireland, 2Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland, 3St James's Hospital, Department of Biochemistry, Dublin, Ireland, 4Trinty College Dublin, School of Medicine, Dublin, Ireland, 5INITIative, Investigator Network Inflammatory bowel disease Therapy in Ireland, Dublin, Ireland, 6St Vincent's University Hospital, Gastroenterology, Dublin, Ireland, 7St James's Hospital, Gastroenterology, Dublin, Ireland, 8Beacon Hospital, Gastroenterology, Dublin, Ireland

P402: Systemic steroids vs. local acting steroids: Relative risk for corticosteroid-related adverse events

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Timeus1, R. Hofmann*2

1Tillotts Pharma AG, Drug Safety, Rheinfelden, Switzerland, 2Tillotts Pharma AG, Medicines Management, Rheinfelden, Switzerland

P403: Intravenous iron infusion in inflammatory bowel disease: efficacy and ferro-economics

ECCO '19 Copenhagen

Year: 2019
Authors:

R. Ranjan*1, D. Rayner1, F. Maw1, A. Dhar1

1County Durham and Darlington NHS Foundation Trust, Gastroenterology, Durham, UK

P404: Stopping 5-aminosalicylates in Crohn’s disease patients starting biologic therapy does not increase the risk of adverse clinical outcomes: analysis of two nationwide population-based cohorts

ECCO '19 Copenhagen

Year: 2019
Authors:

R. Ungaro*1, B. Limketkai2, C. B. Jensen3, C. Yzet4, K. H. Allin3, M. Agrawal5, J. Burisch3, T. Ullman6, T. Jess3, J-F. Colombel1

1Icahn School of Medicine at Mount Sinai, Division of Gastroenterology, New York, USA, 2Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, USA, 3Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, 4Amiens University Hospital, Amiens, France, 5Division of Gastroenterology and Hepatology, Lenox Hill Hospital, New York, USA, 6Division of Gastroenterology, Montefiore Medical Center, Albert Einstein College of Medicine, New York, USA

P405: Sustainability of biologic therapies is less in UC than CD patients independent of prior biologic experience

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Doherty*1, M. Buckley1, G. Cullen1, D. Keegan1, K. Byrne1, G. Horgan1, H. Mulcahy1, J. Sheridan1, G. A. Doherty1,2

1Centre for Colorectal Disease, St Vincent’s University Hospital and School of Medicine, University College Dublin, Gastroentrology, Dublin, Ireland, 2UCD Clinical Professor, School of Medicine, University College Dublin, School of Medicine, University College Dublin, Dublin, Ireland

P406: General health status in patients with moderate to severe ulcerative colitis receiving ustekinumab: results from the Phase 3 UNIFI induction and maintenance studies

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Danese*1, B. E. Sands2, R. W. Leong3,4, H. Zhang5, J. Johanns5, P. Szapary5, C. Marano5, C. Han6

1Humanitas Research Hospital, Milan, Italy, 2Icahn School of Medicine at Mount Sinai, New York, USA, 3Concord Hospital, Sydney, Australia, 4Macquarie University Hospital, Sydney, Australia, 5Janssen Research and Development, LLC, Spring House, USA, 6Janssen Global Services, LLC, Malvern, USA

P407: Real-world safety of tofacitinib in inflammatory bowel diseases: a multi-centre study

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Yarur*1, L. Bixuan1, P. Deepak2, A. Khatiwada2, G. Christophi2, M. Ciorba2, R. Ungaro3, M. Fenster3, C. Dimopoulos3, G. Syal4, R. Hirten3, J-F. Colombel3, C. Ha4, R. Weisshof5, J. Pekow5, A. Patel6, P. Beniwal-Patel1, B. Cohen3

1Medical College of Wisconsin, Gastroenterology, Milwaukee, USA, 2Washington University in St Louis School of Medicine, Gastroenterology, Saint Louis, USA, 3Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, USA, 4CedarsSinai Medical Center, Gastroenterology, Los Angeles, USA, 5University of Chicago, Section of Gastroenterology, Hepatology, and Nutrition, Chicago, USA, 6Brooke Army Medical Center, Gastroenterology, Fort Sam Houston, USA

P408: Switching from infliximab originator to a biosimilar does not affect efficacy, pharmacokinetics and immunogenicity in paediatric patients with inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

K. van Hoeve*1,2, E. Dreesen3, I. Hoffman1, M. Ferrante2,4, A. Gils3, S. Vermeire2,4

1University Hospitals Leuven, Department of Paediatric gastroenterology and Hepatology and Nutrition, Leuven, Belgium, 2Catholic University of Leuven (KU Leuven), TARGID, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), Leuven, Belgium, 3Catholic University of Leuven (KU Leuven), Laboratory for Therapeutic and Diagnostic Antibodies, Department of Pharmaceutical and Pharmacological Sciences, Leuven, Belgium, 4University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium

P409: Non-medical reverse switch between the originator infliximab and its biosimilar in patients with inflammatory bowel disease: clinical outcomes and therapeutic drug monitoring

ECCO '19 Copenhagen

Year: 2019
Authors:

L. Gonczi*1, A. Ilias1, K. Szanto2, Z. Kurti1, P. A. Golovics3, K. Farkas2, E. Schafer3, Z. Szepes2, B. Szalay4, A. Vincze5, T. Szamosi3, T. Molnar2, P. Lakatos6

1Semmelweis University, First Department of Internal Medicine, Budapest, Hungary, 2University of Szeged, First Department of Medicine, Szeged, Hungary, 3Military Hospital – State Health Centre, Department of Gastroenterology, Budapest, Hungary, 4Semmelweis University, Department of Laboratory Medicine, Budapest, Hungary, 5University of Pecs, First Department of Medicine, Pecs, Hungary, 6McGill University Health Center, Division of Gastroenterology, Montreal, Canada

P410: Extraintestinal manifestations and quality of life in patients with ulcerative colitis: 1-year data from ICONIC

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Ghosh*1, F. Casellas2, C. O’Shea3, M. Leonard3, J. Petersson4, L. Peyrin-Biroulet5

1University of Birmingham, Birmingham, UK, 2Crohn-Colitis Care Unit (UACC), Hospital Universitari Vall, Vall d'Hebron, Spain, 3AbbVie Ltd., Dublin, Ireland, 4AbbVie Inc., North Chicago, Illinois, USA, 5University of Lorraine, Nancy, France

P411: Using wearable devices to assess pain in inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

O. V. Yvellez*1, P. H. Sossenheimer1, M. Andersen Jr1, K. El Jurdi1, A. Mayampurath2, D. T. Rubin1

1Inflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, USA, 2Litmus Health, Inc., Austin, TX, USA