¹GI Unit, 3rd Academic Department of Internal Medicine, Athens, Greece, ²General Hospital ‘Laikon’, Neurological Unit,, Athens, Greece, ³Sotiria Hospital, National and Kapodistrian University of Athens, GI-Unit, 3rd Academic Department of Internal Medicine, Athens, Greece

¹University Hospital CHU of Liège, Liège, Belgium, ²University of California San Diego, La Jolla, USA, ³Academic Medical Center, Amsterdam, The Netherlands, ⁴AZ Delta Roeselare-Menen, Menen, Belgium, ⁵AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, ⁶AbbVie Inc., North Chicago, USA, ⁷University of Western Ontario, Robarts Research Institute, London, Canada

¹University Hospitals Leuven, Leuven, Belgium, ²University Hospital Centre Zagreb, Zagreb, Croatia, ³Kitasato University Kitasato Institute Hospital, Tokyo, Japan, ⁴Takeda Development Center Americas Inc., Cambridge, USA, ⁵Takeda Pharmaceuticals International AG, Zurich, Switzerland, ⁶Takeda Pharmaceuticals International, Deerfield, USA, ⁷University of California - San Diego, La Jolla, USA

¹St Mark's Hospital, Inflammatory Bowel Disease, London, UK, ²University Hospitals Leuven, Gastroenterology and Hepatology, Leuven, Belgium, ³KU Leuven, Chronic Diseases, Metabolism and Ageing, Leuven, Belgium, ⁴Hull and East Yorkshire Hospitals NHS Trust, Inflammatory Bowel Disease Unit, Hull, UK, ⁵University of Hull and York, Hull York Medical School, Hull, UK, ⁶University of Turin, Surgical Sciences, Turin, Italy, ⁷University Hospital Zurich, Medicine, Zurich, Switzerland, ⁸University of Ioannina School of Medical Sciences, Gastroenterology, Ioannina, Greece, ⁹University Hospital Galway, Gastroenterology, Galway, Ireland, ¹⁰Grand Hopital de Charleroi, Gastroenterology and Hepatology, Charleroi, Belgium, ¹¹University Hospital Saint-Luc, Gastroenterology and Hepatology, Bruxelles, Belgium, ¹²Hospital de Clinicas de Porto Alegre, Gastroenterology, Rio Grande do Sul, Brazil, ¹³University Messina, Clinical Unit for Chronic Bowel Disorders, Messina, Italy, ¹⁴University of Parma, Gastroenterology and Endoscopy Unit, Parma, Italy, ¹⁵Sacro Cuore Don Calabria of Negrar, Negrar, Italy, ¹⁶Hannover Medical School, Gastroenterology, Hepatology and Endocrinology, Hannover, Germany, ¹⁷Sheba Medical Centre, Gastroenterology, Ramat Gan, Israel

¹Humanitas University, Milan, Italy, ²Takeda Pharmaceuticals International AG, Zurich, Switzerland, ³Takeda Development Centre Europe Ltd., London, UK, ⁴Takeda Pharmaceuticals International, Deerfield, USA, ⁵Icahn School of Medicine at Mount Sinai, New York, USA

¹Herlev and Gentofte Hospital, Gastroentrology, Copenhagen, Denmark, ²Odense University Hospital, Gastroentrology, Odense, Denmark

¹Western University, London, Ontario, Canada, ²University of California San Diego, La Jolla, CA, USA, ³University Hospital Schleswig-Holstein, Kiel, Germany, ⁴AbbVie Inc., North Chicago, IL, USA, ⁵Amsterdam University Medical Centers, Amsterdam, The Netherlands

¹Analysis Group, Montreal, Canada, ²Takeda Pharmaceutical Company, Ltd., Deerfield, IL, USA

¹IBD Center Humanitas Clinical and Research Centre, Rozzano, Milan, Italy, ²St Mark's Hospital, Harrow, UK, ³Department of Medicine I, Agaplesion Markus Hospital, Goethe-University, Frankfurt am Main, Germany, ⁴CHU de Liège, Liège, Belgium, ⁵Academic Medical Centre, Amsterdam, The Netherlands, ⁶Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel, ⁷The Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel, ⁸Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland, ⁹Global Medical Affairs Gastroenterology, Ferring Pharmaceuticals Center S.A, Saint-Prex, Switzerland, ¹⁰Department of Gastroenterology and Inserm u954, Lorraine University, Nancy, France

¹IBD Unit, Hull & East Yorkshire Hospitals NHS Trust, Hull, UK, ²Hull York Medical School, University of Hull and York, Hull, UK, ³Nottingham University Hospitals NHS Trust, Nottingham, UK, ⁴South Eastern Trust, Belfast, UK, ⁵Royal Shrewsbury Hospitals NHS Trust, Shrewsbury, UK, ⁶Pennine Acute Hospitals NHS Trust, Manchester, UK, ⁷County Durham and Darlington NHS Foundation Trust, Durham, UK, ⁸Colchester Hospital University Foundation Trust, Colchester, UK, ⁹Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK, ¹⁰Airedale NHS Foundation Trust, Airedale, UK, ¹¹Sheffield Teaching Hospitals NHS Trust, Sheffield, UK, ¹²Royal London Hospital, Barts Health NHS Trust, London, UK, ¹³Addenbrookes Hospital, University of Cambridge, Cambridge, UK, ¹⁴Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

¹Erasmus MC-Sophia Children’s Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands, ²GI Care for Kids and Emory University Hospital, Atlanta, USA, ³Janssen Scientific Affairs, LLC, Horsham, USA, ⁴Janssen Pharmaceuticals, Horsham, USA, ⁵Janssen Research and Development, LLC, Spring House, USA, ⁶Sapienza University of Rome, Rome, Italy

¹Isarklinikum München, Gastroenterology, Munich, Germany, ²IBD center Munich, Munich, Germany, ³Gastroklinik Pasing, Munich, Germany

¹University Hospital Southampton, Gastroenterology, Southampton, UK, ²University of Southampton, NIHR Southampton Biomedical Research Centre, Southampton, UK, ³University of Southampton, Faculty of Medicine, Southampton, UK

¹University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ²KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium, ³KU Leuven, Department of Human genetics, Laboratory for Complex Genetics, Leuven, Belgium, ⁴Department of Oncology, Laboratory of Lipid Metabolism and Cancer, Leuven, Belgium, ⁵KU Leuven, Department of Microbiology and Immunology, Laboratory of Clinical Immunology, Leuven, Belgium

¹Hospital de Santa Maria, Gastroenterology, Lisbon, Portugal

¹Juntendo University, Gastroenterology, Tokyo, Japan, ²Juntendo Urayasu Hospital, Gastroenterology, Urayasu, Japan

¹Boston Medical Center, Section of Gastroenterology, Boston University School of Medicine, Boston, MA, USA, ²Cajuru University Hospital, Pontifical Catholic University of Paraná (PUCPR), IBD Outpatient Clinics, Colorectal Surgery Unit, Curitiba, Brazil, ³Monash Health, Department of Gastroenterology, Melbourne, VIC, Australia, ⁴Monash University, School of Clinical Sciences at Monash Health, Melbourne, VIC, Australia, ⁵Pfizer Inc., Collegeville, PA, USA

¹LUMC, Gastroenterology-Hepatology, Leiden, The Netherlands, ³National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Birmingham, UK, ⁴University Hospitals Birmingham, Birmingham, UK, ⁵University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, UK, ⁶University of Birmingham, Institute of Applied Health Research, Birmingham, UK, ⁷LUMC, Department of Biomedical Data Sciences, Leiden, The Netherlands

¹Luigi Sacco University Hospital, General Surgery, Milano, Italy, ²Hôpiteau de Paris (AP-HP), Beaujon Hospital, University Denis Diderot, Department of Colorectal Surgery, Pôle des Maladies de l'Appareil Digestif (PMAD),, Paris, France, ³Luigi Sacco University Hospital, Gastroenterology, Milano, Italy, ⁴ICS Maugeri, General Surgery Department, Pavia, Italy

¹Virgen Macarena Hospital, Gastroenterology, Seville, Spain, ²Virgen Macarena Hospital, Pharmacy Unit, Seville, Spain, ³University of Seville, Seville, Spain, ⁴Virgen Macarena Hospital, Preventive Medicine and Public Health, Seville, Spain, ⁵Virgen Macarena Hospital, Statistics, Seville, Spain