P0641: Efficacy of Vedolizumab and Ustekinumab Following Cyclosporine Induction in Acute Severe Ulcerative Colitis: A Retrospective Cohort Study.ECCO'25Year: 2025
Authors: Harb, M.(1)*;Bazin, T.(1);Solene, D.(1);Bresteau, C.(1);El Khatib, M.(1);Bourdillel, J.(1);Colas, C.(1);Corcos, O.(1);Billiauws, L.(1);Joly, F.(1);Nuzzo, A.(1);
(1)Hopital Beaujon APHP, Clichy, Paris, France;
P0642: Assessment of the real-world effectiveness of upadacitinib in patients with moderate-severe ulcerative colitis in a global real-world settingECCO'25Year: 2025
Authors: Seidelin, J.B.(1)*;Marin-Jimenez, I.(2);Dawod, F.(3);Lukanova, R.(3);Jones, W.(3);Morriset, P.(4);Sharma, D.(4);Siegel, C.(5);
(1)Rigshospitalet, University of Copenhagen- Department of Digestive Diseases- Transplantation and General Surgery- IBD Section, Copenhagen, Denmark;(2)Hospital General Universitario Gregorio Marañón, Gastroenterology, Madrid, Spain;(3)Adelphi Real World, Gastroenterology, Bollington, United Kingdom;(4)AbbVie Inc., Gastroenterology, North Chicago, United States;(5)Dartmouth Hitchcock Medical Center, Gastroenterology, Lebanon, United States;
P0643: Development of a personalized infliximab dosing algorithm for Acute Severe Ulcerative Colitis: results of a multi-center pharmacometrics analysisECCO'25Year: 2025
Authors: Niyigena , E.(1);Hoffert, Y.(1);Peyrin-Biroulet , L.(2);Afif , W.(3);Roblin , X.(4);Hanžel , J.(5);Papamichael , K.(6);Kobayashi , T.(7);Wang , Z.(1);Verstockt , B.(8);Vermeire , S.(8);Vande Casteele , N.(9);Battat , R.(10);Dreesen, E.(1)*;
(1)KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Leuven, Belgium;(2)Nancy University Hospital, INFINY Institute, Vandœuvre-lès-Nancy, France;(3)McGill University Health Centre, Division of Gastroenterology, Montreal, Canada;(4)University Hospital of Saint Etienne, Gastroenterology, Saint Etienne, France;(5)University Medical Centre Ljubljana- University of Ljubljana, Department of Gastroenterology, Ljubljana, Slovenia;(6)Harvard Medical School, Center for Inflammatory Bowel Diseases- Division of Gastroenterology, Boston, United States;(7)Kitasato Institute Hospital, Center for Advanced IBD Research and Treatment, Tokyo, Japan;(8)University Hospitals Leuven, Translational Research in Gastrointestinal Disorders- Department of Chronic Diseases and Metabolism, Leuven, Belgium;(9)University of California, Department of Medicine, La Jolla, United States;(10)University of Montreal Hospital Centre, Center for Clinical Excellence and Translational Research in Inflammatory Bowel Diseases, Montreal, Canada;
[1] Choy et al. Lancet Gastroenterol Hepatol. 2024;9(11):981–996
P0645: CDAI underestimates disease activity in overweight patients with Crohn’s Disease when compared to endoscopic assessmentECCO'25Year: 2025
Authors: Campbell, I.(1)*;Brownson, E.(2);Wirz, A.(3);Seenan, J.P.(1);MacDonald, J.(1);Gerasimidis, K.(4);
(1)Queen Elizabeth University Hospital, Gastroenterology, Glasgow, United Kingdom;(2)Glasgow Royal Infirmary, Gastroenterology, Glasgow, United Kingdom;(3)Gartnavel General Hospital, Gastroenterology, Glasgow, United Kingdom;(4)University of Glasgow, Human Nutrition- School of Medicine- College of Medical- Veterinary and Life Sciences, Glasgow, United Kingdom;
1. Best WR, Becktel JM, Singleton JW, Kern F Jr. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology. 1976;70(3):439-444.
2. Lomer MCE, Cahill O, Baschali A, et al. A multicentre Study of Nutrition Risk Assessment in Adult Patients with Inflammatory Bowel Disease Attending Outpatient Clinics. Ann Nutr Metab. 2019;74(1):18-23. doi:10.1159/000495214
P0646: Significant mental health and fatigue burden found in tertiary paediatric IBD service in AustraliaECCO'25Year: 2025
Authors: Au Yeung, S.T.(1,2);You, D.(2,3);Mahmood, D.(2);Tano, M.(1);Chidgey, T.(1);Magoffin, A.(1);O’Loughlin, E.(1);Thacker , K.(1);Dutt, S.(1,3)*;
(1)The Children's Hospital at Westmead, Department of Gastroenterology, Westmead, Australia;(2)The Children's Hospital at Westmead, Department of Psychological Medicine, Westmead, Australia;(3)University of Sydney, School of Medicine- Children's Hospital Westmead Clinical School, Sydney, Australia;
1. Butwicka A, Olén O, Larsson H, et al. Association of childhood-onset inflammatory bowel disease with risk of psychiatric disorders and suicide attempt. JAMA Pediatr. 2019 Oct;173(10):969-978. doi: 10.1001/jamapediatrics.2019.2662.
2. Cooney R, Tang D, Barrett K, Russell RK. Children and young adults with inflammatory bowel disease have an increased incidence and risk of developing mental health conditions: a UK population-based cohort study. Inflamm Bowel Dis. 2024 Aug;30(8):1264-1273. doi: 10.1093/ibd/izad169.
3. Uhlir V, Stallmach A, Grunert PC. Fatigue in patients with inflammatory bowel disease-strongly influenced by depression and not identifiable through laboratory testing: a cross-sectional survey study. BMC Gastroenterol. 2023 Aug 22;23(1):288. doi: 10.1186/s12876-023-02906-0. PMID: 37608313; PMCID: PMC10463723.
P0647: Impact of Age and Comorbidities on Treatment Outcomes and Mortality in Patients Admitted for Ulcerative Colitis Flares: A 20-Year Retrospective Cohort StudyECCO'25Year: 2025
Authors: Tejero Jurado, R.(1)*;el Fallous el Mraghid, M.(1);Carrillo Cubero, B.(1);Alañón Martínez, P.(1);Marín Pedrosa, S.(1);Soto Escribano, P.(1);Benítez Cantero, J.M.(1);Iglesias Flores, E.M.(1);Gros Alcalde, B.(1);
(1)Reina Sofia University Hospital, Gastroenterology, Córdoba - Córdoba, Spain; Maimonides Institute for Biomedical Research at Cordoba
P0648: The Safety and Effects of a Dual-Strain Probiotic Versus Placebo on Fatigue in Patients with Ulcerative ColitisECCO'25Year: 2025
Authors: Carroll, A.(1)*;Walker, C.(1);Magdeldin, H.(1);Breslin, N.(1);O'Donnell, S.(1);Ryan, B.(1);McNamara, D.(1);Corr, S.(2);O'Connor, A.(1);
(1)Tallaght University Hospital, Gastroenterology, Dublin, Ireland;(2)Trinity College Dublin, Microbiology, Dublin, Ireland; Tallaght University Hospital
1. Gibble TH, Minyang S, Xhou X, Naegeli AN, Dubey S, Lewis JD. Association of Fatigue with disease activity and clinical manifestations in patients with Crohn's Disease and Ulcerative Colitis: An Observational Cross-Sectional Study in the United States. Current Medical Research and Opinion. 2024;9:1537-1544.
2. Römkens TEH, van Vugt-van Pinxteren MWJ, Nagengast FM, van Oijen MGH, de Jong DJ. High prevalence of fatigue in inflammatory bowel disease: A case control study. Journal of Crohn's and Colitis. 2011;5(4):332-7.
3. Groeger D, O'Mahony L, Murphy EF, Bourke JF, Dinan T, Kiely B, Shanahan F, Quigley EM. Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut. Gut Microbes. 2013;4(4):325-339.
4. Wang H, Braun C, Murphy EM, Enck P. Bifidobacterium longum 1714™ Strain Modules Brain Activity of Healthy Volunteers During Social Stress. American Journal of Gastroenterology. 2019;144(7):1152-1162.
P0649: Acceptability and Tolerance of Risankizumab Treatment Administered via On-Body Injector in Patients with Crohn’s Disease: Results of the Nationwide ACCEPT-OBI StudyECCO'25Year: 2025
Authors: Buisson, A.(1)*;Gebara, K.(2);Peyrin-Biroulet, L.(3);Boschetti, G.(4);Gilletta de Saint Joseph, C.(5);Brixi, H.(6);Juillerat, P.(7);Serrero, M.(8);Vuitton, L.(9);Hébuterne, X.(10);Caillo, L.(11);Blain, A.(12);Laharie, D.(13);Pereira, B.(1);Fumery, M.(14);
(1)CHU Clermont-Ferrand, IBD Unit, Clermont-Ferrand, France;(2)CHU Montpellier, IBD Unit, Montpellier, France;(3)CHU Nancy, IBD Unit, Nancy, France;(4)HCL Lyon Sud, IBD Unit, Lyon, France;(5)CHU Toulouse, IBD Unit, Toulouse, France;(6)CHU Reims, IBD Unit, Reims, France;(7)Hospital, IBD Unit, switzerland, Switzerland;(8)AP-HM, IBD Unit, Marseille, France;(9)CHU Besançon, IBD Unit, Besançon, France;(10)CHU Nice, IBD Unit, Nice, France;(11)CHU Nïmes, IBD Unit, Nîmes, France;(12)IMM, IBD Unit, Paris, France;(13)CHU Bordeaux, IBD Unit, Bordeaux, France;(14)CHU Amiens, IBD Unit, Amiens, France; GETAID
P0650: Comparative study between Kono-S and latero-lateral isoperistaltic anastomosis in the treatment of terminal ileum Crohn's Disease patients: perioperative complications and short-term results.ECCO'25Year: 2025
Authors: Colombo, F.(1);Gatti, F.(1)*;Lazzarino, M.(1);Guerci, C.(1);Gridavilla, D.(2);Maconi, G.(2);Danelli, P.(1);
(1)ASST Fatebenefratelli Sacco, Department of General Surgery- Department of Biomedical and Clinical Sciences 'L. Sacco'- University of Milan, Milan, Italy;(2)ASST Fatebenefratelli Sacco, Gastrointestinal Unit- L. Sacco University Hospital- Department of Biochemical and Clinical Sciences- University of Milan, Milan, Italy; .
1. Nos P, Domenech E. Postoperative Crohn’s disease recurrence: a practical approach. World J Gastroenterol 2008;14(36):5540–5548.
2. Kono T, Fichera A, Maeda K, et al. Kono-S anastomosis for surgical prophylaxis of anastomotic recurrence in Crohn’s disease: an International Multicenter Study. J Gastrointest Surg 2016;20 (04):783–790.
3. Alshantti A, Hind D, Hancock L, Brown SR. The role of Kono-S anastomosis and mesenteric resection in reducing recurrence after surgery for Crohn's disease: a systematic review. Colorectal Dis. 2021 Jan;23(1):7-17.
4. Baloyiannis I, Perivoliotis K, Sarakatsianou C, Chatzinikolaou C, Tzovaras G. The Reduction of Anastomosis-Related Morbidity Using the Kono-S Anastomosis in Patients with Crohn's Disease: A Meta-Analysis. J Clin Med. 2024 Apr 23;13(9):2461.
P0651: Evaluating tryptophan as a biomarker for treatment success in Inflammatory Bowel Disease patients undergoing therapyECCO'25Year: 2025
Authors: Maaß, C.(1)*;Hatem, Y.(2);Aden, K.(3);Marquardt, J.U.(2);Solbach, P.(2);
(1)Universitätsklinikum Lübeck, Medizinische Klinik I, Lübeck, Germany;(2)University Hospital Schleswig-Holstein- Campus Luebeck- Luebeck- Germany., Department of Medicine I, Lübeck, Germany;(3)Christian Albrechts University and University Hospital Schleswig-Holstein- Campus Kiel- Kiel- Germany., Department of Internal Medicine I-, Kiel, Germany;
Wang S, van Schooten FJ, Jin H, Jonkers D, Godschalk R. The Involvement of Intestinal Tryptophan Metabolism in Inflammatory Bowel Disease Identified by a Meta-Analysis of the Transcriptome and a Systematic Review of the Metabolome. Nutrients. 2023 Jun 26;15(13):2886. doi: 10.3390/nu15132886. PMID: 37447212; PMCID: PMC10346271.
Ding, Xueyan, Bin, Peng, Wu, Wenwen, Chang, Yajie, Zhu, Guoqiang, Tryptophan Metabolism, Regulatory T Cells, and Inflammatory Bowel Disease: A Mini Review, Mediators of Inflammation, 2020, 9706140, 10 pages, 2020. https://doi.org/10.1155/2020/9706140
Susanna Nikolaus, Berenice Schulte, Natalie Al-Massad, Florian Thieme, Dominik M. Schulte, Johannes Bethge, Ateequr Rehman, Florian Tran, Konrad Aden, Robert Häsler, Natalie Moll, Gregor Schütze, Markus J. Schwarz, Georg H. Waetzig, Philip Rosenstiel, Michael Krawczak, Silke Szymczak, Stefan Schreiber,Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases,Gastroenterology,Volume 153, Issue 6,2017,Pages 1504-1516.e2,ISSN 0016-5085,https://doi.org/10.1053/j.gastro.2017.08.028.
P0652: Norovirus Infection May Be Responsible For More Severe Flares of Ulcerative ColitisECCO'25Year: 2025
Authors: Gawron-Kiszka, M.(1)*;Nowakowska-Duława, E.(1);Boryczka, G.(1);Dylińska-Kala, K.(1);Modrzejewski, M.(1);Tłuczykont, M.(1);Iwanicki, T.(2);Hartleb, M.(1);
(1)University Clinical Center prof. K. Gibiński of the Medical University of Silesia, Department of Gastroenterology and Hepatology, Katowice, Poland;(2)Faculty of Health Sciences of Medical University of Silesia, Department of Biochemistry and Medical Genetics, Katowice, Poland;
1.Tarris, G.; de Rougemont,A.; Charkaoui, M.; Michiels, C.;Martin, L.; Belliot, G. Enteric Viruses and Inflammatory Bowel Disease. Viruses 2021;13:104. DOI: 10.3390/v13010104
2. Craviotto, V.; Furfaro, F.; Loy, L.; Zilli, A.; Peyrin-Biroulet, L.; Fiorino, G.; Danese, S.; Allocca, M. Viral infections in inflammatory bowel disease: Tips and tricks forcorrect management. World J Gastroenterol 2021;27(27): 4276-4297. DOI: 10.3748/wjg.v27.i27.4276
3. Dehghani ,T.; Gholizadeh, O.; Daneshvar, M.; Nemati M.M.; Akbarzadeh, S.; et al. Association Between Inflammatory Bowel Disease and Viral Infections. Current Microbiology 2023;80:195. DOI: 10.1007/s00284-023-03305-0
P0653: Patients with ileo-anal J-Pouch display altered, higher pouch contractility than controls as measured with motility MRI.ECCO'25Year: 2025
Authors: Blad, W.(1)*;Menys, A.(2);Weston, W.(3);Dennis, C.(3);Naim, I.(2);Taylor, S.A.(3);
(1)UCLH, Gastroenterology, London, United Kingdom;(2)Motilent, Motilent, London, United Kingdom;(3)UCL, Centre for Medical imaging, London, United Kingdom;
1. Herfarth, Hans MD, PhD, FACG1; Long, Millie D. MD, MPH, FACG1; Hansen, Jonathan J. MD, PhD1; Anderson, Chelsea PhD1; English, Emily BA, MSW1; Buse, John B. MD, PhD2; Barnes, Edward L. MD, MPH, FACG1. Efficacy and Safety of Liraglutide in Patients With an Ileal Pouch-Anal Anastomosis and Chronic High Bowel Frequency: A Placebo-Controlled, Crossover, Proof-of-Concept Study. The American Journal of Gastroenterology 119(9):p 1935-1938, September 2024. | DOI: 10.14309/ajg.0000000000002801
P0654: Switching from intravenous to subcutaneous infliximab: physicians' practice and patients' satisfaction - Results from a nationwide transectional study.ECCO'25Year: 2025
Authors: Hupé, M.(1)*;Laharie, D.(2);Wils, P.(3);Uzzan, M.(4);Peyrin-Biroulet, L.(5);Kirchgesner, J.(6);Atanasiu, C.(7);Cadiot, G.(8);Richard, N.(9);Simon, M.(10);Caillo, L.(11);Nancey, S.(12);de Maissin, A.(13);Vuitton, L.(14);Hébuterne, X.(15);Alric, H.(16);Coffin, B.(17);Gellouz, S.(18);Buisson, A.(19);
(1)CHU Grenoble, IBD Unit, Grenoble, France;(2)CHU Bordeaux, Gastroentérologie et Nutrition, Pessac, France;(3)CHU Lille, Hépato-gastroentérologie, Lille, France;(4)Henri Mondor Hospital, Gastroentérologie, Créteil, France;(5)CHU Nancy, Hépato-gastroentérologie, Nancy, France;(6)Hopital Saint Antoine, Hépato-gastroentérologie, Paris, France;(7)Hopital Saint Joseph, Hépato-gastroentérologie, Paris, France;(8)CHU Reims, Gastroentérologie, Reims, France;(9)CHU Rouen, Hépato-gastroentérologie, Rouen, France;(10)Institut Mutualiste Montsouris, Gastroentérologie, Paris, France;(11)CH Nimes, Hépato-gastroentérologie, Nimes, France;(12)CHU Lyon Sud, Gastroentérologie, Lyon, France;(13)CH Vendée, Hépato-gastroentérologie, La-Roche-Sur-Yon, France;(14)CHU Besançon, Gastroentérologie, Besançon, France;(15)CHU Nice, Hépato-gastroentérologie, Nice, France;(16)Hôpital Européen Georges Pompidou, Hépato-gastroentérologie, Paris, France;(17)Hôpital Louis Mourier, Gastroentérologie, Paris, France;(18)Groupe Hospitalier Rance Emeraude, Hépato-gastroentérologie, Saint-Malo, France;(19)CHU Clermont-Ferrand, Hépato-gastroentérologie, Clermont-Ferrand, France; GETAID
P0655: VTE thromboprophylaxis in patients with inflammatory bowel disease admitted to hospital; can we increase adherence with guidelines?ECCO'25Year: 2025
Authors: Das, A.(1)*;Florez, C.S.(1);Leslie, F.(1);
(1)Manchester University NHS Foundation Trust, Gastroenterology, MANCHESTER, United Kingdom;
1. Hannah Gordon, Johan Burisch, Pierre Ellul, et al. ECCO Guidelines on Extraintestinal Manifestations in Inflammatory Bowel Disease,Journal of Crohn's and Colitis, Volume 18, Issue 1, January 2024, Pages 1–37, https://doi.org/10.1093/ecco-jcc/jjad108
2. Olivera, P.A., Zuily, S., Kotze, P.G. et al. International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease.Nat Rev Gastroenterol Hepatol 18, 857–873 (2021). https://doi.org/10.1038/s41575-021-00492-8
P0656: Adalimumab mono vs. combination therapy in Crohn's Disease: Real world experienceECCO'25Year: 2025
Authors: Babic, F.(1)*;Cacic, P.(1);Biscanin, A.(1);Kralj, D.(1);Ogresta Kordej, D.(1);Dorosulic, Z.(1);Hrabar, D.(1);Tomasic, V.(1);
(1)University Hospital Center Sestre Milosrdnice, Department of Gastroenterology and Hepatology, Zagreb, Croatia;
1.Gordon H, Minozzi S, Uri Kopylov, et al. ECCO Guidelines on Therapeutics in Crohn’s Disease: Medical Treatment. Journal of Crohn’s and colitis. Published online June 15, 2024. doi:https://doi.org/10.1093/ecco-jcc/jjae091
2. Matsumoto T, Motoya S, Watanabe K, et al. Adalimumab Monotherapy and a Combination with Azathioprine for Crohn’s Disease: A Prospective, Randomized Trial. Journal of Crohn’s and Colitis. 2016;10(11):1259-1266. doi:https://doi.org/10.1093/ecco-jcc/jjw152
P0657: Quality of ileocolic resection in Crohn’s disease- A systemic review and meta-analysisECCO'25Year: 2025
Authors: Lingam, G.(1)*;De Burlet, K.(1);Shakir, T.(2);Khattab, M.(3);Yiu, A.(4);Giannarou, S.(5);Francis, N.(6,7);Sahnan, K.(1);
(1)St Mark's Hospital and Academic Institute, Colorectal surgery, London, United Kingdom;(2)University College London, Colorectal Surgery, London, United Kingdom;(3)Yeovil District Hospital NHS Foundation Trust, Colorectal Surgery, Yeovil, United Kingdom;(4)Ashford and St Peter's Hospitals NHS Foundation Trust, General Surgery, Surrey, United Kingdom;(5)Imperial College London, Department of surgery and cancer, London, United Kingdom;(6)The Griffin Institute, Colorectal Surgery, London, United Kingdom;(7)University College London, Department of surgical biotechnology, London, United Kingdom;
P0658: Comparison of the Efficacy and Safety of Immunomodulator Use in Geriatric and Non-Geriatric Patients with Inflammatory Bowel DiseaseECCO'25Year: 2025
Authors: Arı, D.(1);Kenarlı, K.(1)*;Bacaksız, F.(2);Arı, S.(3);Gökbulut, V.(1);Öztürk, Ö.(1);Özderin Özin, Y.(1);Kalkan, İ.H.(4);
(1)Ankara Bilkent City Hospital, Gastroenterology, Ankara, Turkey;(2)Diyarbakır Gazi Yaşargil Training and Research Hospital, Gastroenterology, Diyarbakır, Turkey;(3)Ankara Training and Research Hospital, Geriatrics, Ankara, Turkey;(4)TOBB Economy and Technology University, Gastroenterology, Ankara, Turkey;
P0659: Exploring Ferric Maltol: A Promising Alternative to IV Iron for Managing Chronic Iron Deficiency Anaemia in Inflammatory Bowel Disease PatientsECCO'25Year: 2025
Authors: Wong, F.(1)*;Kamperidis, N.(1);Angela, C.(1);Young, L.(1);Tyrrell, T.(1);Passos, D.(1);Al-Zarrad, D.(1);
(1)St Marks Hospital- London Northwest University Healthcare NHS Trust, Gastroenterology, London, United Kingdom;
Crohn's & Colitis UK. Crohn’s & Colitis UK [Internet]. www.crohnsandcolitis.org.uk. 2022. Available from: https://crohnsandcolitis.org.uk/Gasche C, Berstad A, Befrits R, Beglinger C,
Dignass A, Erichsen K, et al. Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases. Inflammatory Bowel Diseases. 2007 Dec;13(12):1545–53.Howaldt S, Domènech E, Martinez N, Schmidt C, Bokemeyer B. Long-Term Effectiveness of Oral Ferric Maltol vs Intravenous Ferric Carboxymaltose for the
Treatment of Iron-Deficiency Anemia in Patients with Inflammatory Bowel Disease: A Randomized Controlled Noninferiority Trial. Inflammatory Bowel Diseases. 2021 May 14.NICE.
Anaemia - Iron deficiency [Internet]. NICE. 2021. Available from: https://cks.nice.org.uk/topics/anaemia-iron-deficiency/
P0660: Comparative Accuracy and Reliability of Handheld versus Cart-Based Ultrasound in assessing Inflammatory Bowel Disease ActivityECCO'25Year: 2025
Authors: Khaing, M.M.(1,2,3)*;Fernandes, R.G.(1,2,3);An, Y.K.(1,2,3);Baraty, B.(4);Bryant, R.V.(5,6);Ghaly, S.(7);Smith, R.L.(8);Srinivasan, A.(9,10,11);Hay, K.(12);Begun, J.(1,2,3);
(1)Mater Hospital Brisbane, Department of Gastroenterology and Hepatology, Brisbane- Queensland, Australia;(2)Mater Research Institute, Clinical Trial Unit for Inflammatory Bowel Disease, Brisbane- Queensland, Australia;(3)The University of Queensland, Faculty of Medicine, Brisbane- Queensland, Australia;(4)Western Sydney Local Health District, Department of Gastroenterology and Hepatology, Blacktown- New South Wales, Australia;(5)The Queen Elizabeth Hospital, Department of Gastroenterology and Hepatology, Adelaide- South Australia, Australia;(6)University of Adelaide, School of Medicine, Adelaide- South Australia, Australia;(7)St Vincent’s Hospital, Department of Gastroenterology and Hepatology, Sydney- New South Wales, Australia;(8)Alfred Hospital, Department of Gastroenterology and Hepatology, Melbourne- Victoria, Australia;(9)Eastern Health, Department of Gastroenterology and Hepatology, Melbourne- Victoria, Australia;(10)The University of Melbourne, Austin Academic Centre, Melbourne- Victoria, Australia;(11)Austin Health, Department of Gastroenterology and Hepatology, Melbourne- Victoria, Australia;(12)Queensland Institute of Medical Research, Statistical Unit, Brisbane- Queensland, Australia;
