¹Blizard Institute, Centre of Immunobiology, London, UK

¹Royal Liverpool University Hospital, Liverpool, UK, ²University of Liverpool, Center for genomics research, Liverpool, UK, ³Institute of Translational medicine, Department of Biostatistics, Liverpool, UK

¹University of Seville, Normal and Pathological Cytology and Histology, Seville, Spain, ²University of Seville, Medicine, Seville, Spain, ³Virgen Macarena Hospital, Gastroenterology unit, Seville, Spain

¹St James's Hospital, Department of Gastroenterology, Dublin, Ireland, ²Trinity College Dublin, Dept of Surgery, Dublin, Ireland, ³INITIative, Investigator Network Inflammatory bowel disease Therapy in Ireland, Dublin, Ireland, ⁴St James Hospital, Surgery, Dublin, Ireland, ⁵St James's Hospital, Gastroenterology, Dublin, Ireland, ⁶St James Hospital, Pathology, Dublin, Ireland

¹National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Immunology and Immunotherapy, Birmingham, UK, ²Institute of Translational Medicine, Gastroenterology, Birmingham, UK, ³Institute of Cancer and Genomics Sciences, University of Birmingham, Birmingham, UK

¹University of Antwerp, Laboratory of Experimental Medicine and Pediatrics, Antwerp, Belgium

¹Marques De Valdecilla Universitary Hospital, Gastroenterology, Santander, Spain, ²Biotechnology and Biomedicine Institute of Cantabria (IBBTEC), Santander, Spain

¹Laboratory of Clinical immunology, University hospital St. Ivan Rilski, Medical university of Sofia, Sofia, Bulgaria, ²Clinic of gastroenterology, University hospital ‘St. Ivan Rilski’, Department of Internal medicine, Medical University of Sofia, Bulgaria, Sofia, Bulgaria

¹Translational Gastroenterology Unit, Gastroenterology, Oxford, UK, ²Clatterbridge Cancer Centre, Oncology, Liverpool, UK, ³Royal Liverpool University Hospital, Gastroenterology, Liverpool, UK, ⁴Churchill Hospital, Oncology, Oxford, UK

¹Tokyo Medical and Dental University, Gastroenterology and Hepatology, Tokyo, Japan, ²Tokyo Medical and Dental University, Radiology, Tokyo, Japan

¹University of São Paulo Medical School, Department of Gastroenterology and Hepatology, São Paulo, Brazil, ²University of São Paulo Medical School, Cardiovascular Magnetic Resonance and Computed Tomography Sector, Heart Institute, InCor, São Paulo, Brazil

¹Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, ²Clinical Hospital Centre Zagreb, Gastroenterology and Hepatology, Zagreb, Croatia

¹Hospital da Senhora da Oliveira, Gastroenterology, Guimarães, Portugal, ²Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga/Guimarães, Portugal, ³ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal

¹John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, UK

¹Gastroenterology, School of Medicine Federico II of Naples, Naples, Italy, ²Pediatrics, School of Medicine Federico II of Naples, Naples, Italy

¹Kyorin University School of Medicine, Tokyo, Japan, ²Kyorin University School of Medicine, The Third Department of Internal Medicine, Tokyo, Japan, ³Kyorin University Hospital, Central Clinical Laboratory, Tokyo, Japan, ⁴Kyorin University School of Medicine, Department of Laboratory Medicine, Tokyo, Japan

¹Hospital Sant Joan de Déu, Unit for Comprehensive Care of Pediatric Inflammatory Bowel Disease. Pediatric Gasatroneterology, Hepatology and Nutrition Unit, Barcelona, Spain

¹Department of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Pathology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ³Department of Endoscopy, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

¹Tokyo Women's Medical University, Institute of gastroenterology, Tokyo, Japan

¹University of Cambridge, Department of Medicine, Cambridge, UK