¹University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ²KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium

¹Virginia Commonwealth University, Internal Medicine, Richmond, USA

¹Medical University Innsbruck, Christian Doppler Laboratory for Mucosal Immunology, Innsbruck, Austria, ²Medical University Innsbruck, Department for Internal Medicine I – Gastroenterology, Hepatology, Endocrinology and Metabolism, Innsbruck, Austria, ³University of Innsbruck, Institute of Pharmacy / Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria, ⁴University of Vienna, Division of Computational Systems Biology, Department of Microbiology and Ecosystem Science, Vienna, Austria, ⁵University Halle, Institute of Biology – General Zoology, Halle (Saale), Germany

¹Blizard Institute, Barts and The London School of Medicine and Dentistry, Centre for Genomics and Child Health, London, UK, ²Blizard Institute, Barts and The London School of Medicine and Dentistry, Centre for Cell Biology and Cutaneous Research, London, UK, ³Department of Histopathology, The Royal London Hospital, London, UK, ⁴Blizard Institute, Barts and The London School of Medicine and Dentistry, Centre for Immunobiology, London, UK

¹Austin Health, Gastroenterology, Heidelberg, Australia, ²St Vincent's Hospital, Immunology Research Centre, Fitzroy, Australia, ³Austin Academic Centre, University of Melbourne, Medicine, Heidelberg, Australia, ⁴University of Melbourne, Department of Medicine, Dentistry and Health Sciences, Parkville, Australia, ⁵The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Department of Microbiology and Immunology, Parkville, Australia

¹Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Gastroenterology, Hangzhou, China, ²Inflammatory Bowel Disease Center of Sir Run Run Shaw Hospital, Hangzhou, China, ³MOE Laboratory of Biosystem Homeostasis and Protection, and Life Sciences Institute, Zhejiang University, Hangzhou, China

¹Charité Universitätsmedizin Berlin, Department for Gastroenterology, Infectiology and Rheumatology, Berlin, Germany, ²Charité Universitätsmedizin Berlin, Department for General and Visceral Surgery, Berlin, Germany, ³Charité Universitätsmedizin Berlin, Department for Pathology, Berlin, Germany, ⁴Charité Universitätsmedizin Berlin, Department for Immunopathology, Berlin, Germany, ⁵Rotes Kreuz Krankenhaus, Department for General and Visceral Surgery, Bremen, Germany

¹Herlev Hospital, University of Copenhagen, Department of Gastroenterology, Herlev, Denmark

¹Leiden University Medical Center, Gastroenterology and Hepatology, Leiden, The Netherlands, ²Leiden University Medical Center, Immunohematology and Blood Transfusion, Leiden, The Netherlands

¹Universidad de Valencia, Medicine, Valencia, Spain, ²CIBERehd, Valencia, Spain, ³Fisabio, Valencia, Spain, ⁴Universidad de Valencia, Pharmacology, Valencia, Spain, ⁵CIBERehd, Badalona, Spain, ⁶Hospital de Sagunto, Sagunto, Spain, ⁷Hospital de Manises, Manises, Spain

¹Tokyo Medical and Dental University, Gastroenterology, Tokyo, Japan

¹Universita' Cattolica del Sacro Cuore, Institute of Medical Pathology, Rome, Italy, ²Università cattolica del Sacro Cuore, Institute of Biochemistry and Clinical Biochemistry, Rome, Italy, ³Fondazione Policlinico A. Gemelli IRCCS, Department of Laboratory Diagnostic and Infectious Diseases, Rome, Italy, ⁴Fondazione Policlinico Universitario Gemelli IRCCS, Gastroenterological Area, Gastroenterological, Endocrino-Metabolical and Nefro-urological Sciences Department, Rome, Italy

¹ISCARE I.V.F. a.s., IBD Clinical and Research Centre, Prague, Czech Republic, ²University Hospitals of Morecambe Bay NHS Foundation Trust, Royal Lancaster Infirmary, Lancaster, UK, ³Institute of Animal Physiology and Genetics, Czech Academy of Sciences, PIGMOD Centre, Laboratory of Cell Regeneration and Plasticity, Libechov, Czech Republic, ⁴Military University Hospital and 2nd Faculty of Medicine, Charles University, Department of Surgery, Prague, Czech Republic, ⁵Institute of Pathology of the First Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic, ⁶Military University Hospital and First Faculty of Medicine, Charles University, Department of Internal Medicine, Prague, Czech Republic, ⁷Institute of Pharmacology, First Faculty of Medicine, Charles University, Prague, Czech Republic, ⁸Institute of Medical Biochemistry and Laboratory Medicine, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic

¹Universitat de Valencia and CIBERehd, Pharmacology, Valencia, Spain, ²Fisabio, Hospital Dr. Peset, Valencia, Spain, ³Hospital Manises, Valencia, Spain, ⁴Hospital La Fe, Valencia, Spain

¹University of Zurich / University Hospital Zurich, Gastroenterology and Hepatology, Zurich, Switzerland

¹Clinic Fundeni Institute- Gastroenterology and Hepatology, Bucuresti, Romania

¹Bispebjerg Hospital, Digestive Disease Center, Copenhagen, Denmark, ²Faculty of Health and Medical Sciences, Department of Biomedical Sciences, Copenhagen, Denmark, ³University of Manchester, Wellcome Trust Centre for Cell-Matrix Research, Manchester, UK, ⁴Herlev Hospital, Department of Pathology, Copenhagen, Denmark, ⁵NNF Center of Basic Metabolic Research, University of Copenhagen, Department of Biomedical Sciences, Copenhagen, Denmark, ⁶Institute of Clinical Physiology, Charité, Berlin, Germany

¹CHA University, Gastroenterology, Seongnam, South Korea, ²Inha University Hospital, Incheon, South Korea

¹University Hospital of Split, Department of Gastroenterology and Hepatology, Split, Croatia, ²University of Split School of Medicine, Department of Pharmacy, Split, Croatia, ³University of Split School of Medicine, Department of Pathophysiology, Split, Croatia, ⁴University Hospital of Split, Department of Laboratory Diagnostics, Split, Croatia

¹IIS Hospital La Fe, Gastroenterology, Valencia, Spain, ²Networked Biomedical Research Centre for Hepatic and Digestive Diseases (CIBEREHD), Madrid, Spain, ³Hospital Universitari i Politècnic La Fe, Inflammatory Bowel Disease Unit, Gastroenterology Department, Valencia, Spain, ⁴IIS Hospital La Fe, Biostatistics, Valencia, Spain, ⁵IIS Hospital La Fe, Biomarkers and Precision Medicine, Valencia, Spain, ⁶University of Valencia, Central Unit for Research in Medicine (UCIM), Valencia, Spain