¹University of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, IL, USA, ²Icahn School of Medicine at Mount Sinai Hospital, Department of Pediatrics and Medicine, New York, NY, USA, ³Charles University, Prague, Czech Republic, ⁴Pfizer Inc., Collegeville, PA, USA

¹Hospital de Galdakao, Gastroenterology, Galdakao, Spain, ²Hospital Clinic, Gastroenterology, Barcelona, Spain, ³Hospital Universitario Ramón y Cajal, Gastroenterology, Madrid, Spain, ⁴Hospital del March, Gastroenterology, Barcelona, Spain, ⁵Hospital Universitario Germans Trias i Pujol, Gastroenterology, Badalona, Spain, ⁶Complejo Hospitalario de Navarra, Gastroenterology, Pamplona, Spain, ⁷Hospital de Cruces, Gastroenterology, Bilbao, Spain, ⁸Hospital Universitario Puerta de Hierro, Gastroenterology, Majadahonda, Spain, ⁹Hospital de la Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain, ¹⁰Hospital Universitario Miguel Servet, Gastroenterology, Zaragoza, Spain, ¹¹Hospital Universitario de La Princesa, Gastroenterology, Madrid, Spain, ¹²Instituto de Investigación Sanitaria Princesa (IIS-IP) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain, ¹³Hospital Clínico Universitario de Santiago de Compostela, Gastroenterology, Santiago de Compostela, Spain, ¹⁴Hospital Montecelo, Gastroenterology, Pontevedra, Spain, ¹⁵Hospital Universitario Reina Sofía, Gastroenterology, Córdoba, Spain, ¹⁶IMIBIC, Córdoba, Spain, ¹⁷Hospital Clínico San Carlos, Gastroenterology, Madrid, Spain, ¹⁸Hospital Marqués de Valdecilla, Gastroenterology, Santander, Spain, ¹⁹Hospital Universitario La Paz, Gastroenterology, Madrid, Spain, ²⁰Hospital Son Llàtzer, Gastroenterology, Palma, Spain, ²¹Hospital Universitari Mutua Terrassa, Gastroenterology, Terrassa, Spain, ²²Centro de Investigación biomédica en red de enfermedades hepáticas y digestivas (CIBERehd), Terrassa, Spain, ²³Hospital de Salamanca, Gastroenterology, Salamanca, Spain, ²⁴Hospital Universitario de Girona, Gastroenterology, Girona, Spain, ²⁵Hospital Arnau de Vilanova, Gastroenterology, Lérida, Spain

¹University of California San Diego, Department of Medicine, La Jolla, USA, ²Robarts Clinical Trials, Inc., London, Canada, ³Beth-Israel Deaconess Medical Center, Harvard Medical School, Center for Inflammatory Bowel Diseases, Division of Gastroenterology, Boston, USA, ⁴University of Pennsylvania, Department of Medicine, Perelman School of Medicine, Philadelphia, USA

¹University California San Diego, La Jolla, California, USA, ²UZ Leuven, KU Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ³Delta Research Partners, LLC, Bastrop, LA, USA, ⁴Nicolae Testemițanu State University of Medicine and Pharmacy, Chisinau, Moldova, Republic of, ⁵Kitasato Institute Hospital Center for Advanced IBD Research and Treatment, Minato-ku, Tokyo, Japan, ⁶Amsterdam University Medical Centers, Amsterdam, The Netherlands, ⁷Eli Lilly and Company, Lilly Biotechnology Center, San Diego, California, USA, ⁸Eli Lilly and Company, Indianapolis, Indiana, USA, ⁹Western University, Robarts Clinical Trials Inc., London, Ontario, Canada

¹University of Leuven, Leuven, Belgium, ²Cedars-Sinai Medical Center, Los Angeles, USA, ³Janssen Research and Development, Spring House, USA, ⁴Concord Hospital, Sydney, Australia, ⁵Macquarie University Hospital, Sydney, Australia, ⁶Auckland City Hospital, Auckland, New Zealand, ⁷University of Auckland, Auckland, New Zealand, ⁸Kyorin University, Tokyo, Japan, ⁹Humanitas Research Hospital, Milan, Italy, ¹⁰Icahn School of Medicine at Mount Sinai, New York, USA, ¹¹Nancy University Hospital, Vandœuvre-lès-Nancy, France

¹Academic Medical Centre, Amsterdam, The Netherlands, ²Humanitas Research Hospital, Gastroenterology, Milano, Italy, ³Mitsubishi Tanabe Europe Ltd., London, UK, ⁴Tokyo Medical and Dental University, Gastroenterology, Tokyo, Japan, ⁵University Kitasato Hospital, Gastroenterology, Tokyo, Japan

¹Medical University of Vienna, Vienna, Austria, ²University of California San Diego, La Jolla, CA, USA, ³Humanitas University, Milan, Italy, ⁴University of Nice Sophia Antipolis, Hospital l’Archet, Nice, France, ⁵Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland, ⁶Clinic of Gastroenterology and Hepatology, Military Medical Academy, Belgrade, Serbia, ⁷Charles University Hospital, Hradec Králové, Czech Republic, ⁸Gastroenterology Center, Nitra, Slovakia, ⁹Nature Coast Clinical Research, Inverness, FL, USA, ¹⁰Seoul National University College of Medicine, Seoul, South Korea, ¹¹Alfred Hospital, Melbourne, VIC, Australia, ¹²Zymo Consulting Group, Newtown Square, PA, USA, ¹³Shire, Zug, Switzerland, ¹⁴Shire, Lexington, MA, USA, ¹⁵Cytel Inc., Cambridge, MA, USA, ¹⁶University Hospitals Leuven, Leuven, Belgium

¹University of Lorraine, Nancy, France, ²Istituto Clinico Humanitas, Milan, Italy, ³CHU de Liège et Université de Liège, Liège, Belgium, ⁴University of Michigan, Ann Arbor, USA, ⁵Icahn School of Medicine at Mount Sinai, New York, USA, ⁶AbbVie Inc., North Chicago, USA

¹Medical University of Vienna, Vienna, Austria, ²University of California San Diego, La Jolla, CA, USA, ³Humanitas University, Milan, Italy, ⁴University of Nice Sophia Antipolis, Hospital l'Archet, Nice, France, ⁵Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland, ⁶Clinic of Gastroenterology and Hepatology, Military Medical Academy, Belgrade, Serbia, ⁷Charles University Hospital, Hradec Králové, Czech Republic, ⁸Gastroenterology Center, Nitra, Slovakia, ⁹Nature Coast Clinical Research, Inverness, FL, USA, ¹⁰Seoul National University College of Medicine, Seoul, South Korea, ¹¹Alfred Hospital, Melbourne, VIC, Australia, ¹²Zymo Consulting Group, Newtown Square, PA, USA, ¹³Shire, Zug, Switzerland, ¹⁴Shire, Lexington, MA, USA, ¹⁵Cytel Inc., Cambridge, MA, USA, ¹⁶University Hospitals Leuven, Leuven, Belgium

¹University California San Diego, La Jolla, California, USA, ²Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, New York, NY, USA, ³Kitasato University, Center for Advanced IBD Research and Treatment, Tokyo, Japan, ⁴Eli Lilly and Company, Lilly Biotechnology Center, San Diego, CA, USA, ⁵Eli Lilly and Company, Indianapolis, IN, USA, ⁶UZ Leuven, KU Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium

¹University of California San Diego, Medicine, San Diego, USA, ²Theravance Biopharma US, Inc., South San Francisco, USA, ³Janssen R&D, Springhouse, USA, ⁴Hospital Clinic Barcelona, Gastroenterology, Barcelona, Spain

¹Humanitas Research Hospital, Milan, Italy, ²Icahn School of Medicine at Mount Sinai, New York, USA, ³Janssen Research & Development, LLC, Spring House, USA, ⁴Janssen Scientific Affairs, LLC, Horsham, USA, ⁵Concord Hospital, Sydney, Australia, ⁶Macquarie University Hospital, Sydney, Australia, ⁷Auckland City Hospital, Auckland, New Zealand, ⁸University of Auckland, Auckland, New Zealand, ⁹Cedars-Sinai Medical Center, Los Angeles, USA, ¹⁰University of Leuven, Leuven, Belgium

¹Kiel University, Institute of Clinical Molecular Biology, Kiel, Germany, ²Yonsei University College of Medicine, Department of Internal Medicine and Institute of Gastroenterology, Seoul, South Korea, ³National Institute of Food and Drug Safety Evaluation, Clinical Research Division, Cheongju, South Korea

¹Academic Medical Center, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ²Amsterdam UMC, location AMC, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ³Amsterdam UMC, Location AMC, Hospital Pharmacy, Amsterdam, The Netherlands, ⁴Projections Research Inc., Phoenixville, USA, ⁵Tergooi Hospital, Blaricum, The Netherlands, ⁶Onze Lieve Vrouwe Gasthuis, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁷Amsterdam UMC, location AMC, Clinical Genetics, Amsterdam, The Netherlands, ⁸Amsterdam UMC, location VuMc, Gastroenterology and Hepatology, Amsterdam, The Netherlands

¹University Teaching Hospital Lueneburg, Department of Internal Medicine and Gastroenterology, Lueneburg, Germany, ²Gastroenterology Practice, Oldenburg, Germany, ³Biostatistik Tuebingen, Tuebingen, Germany, ⁴AbbVie Deutschland GmbH & Co.KG, Medical Department Gastroenterology, Wiesbaden, Germany

¹University of Alberta, Paediatrics, Edmonton, Canada, ²Hospital for Sick Children, University of Toronto, Paediatrics, Toronto, Canada, ³The Children's Hospital University of Manitoba, Paediatrics, Winnipeg, Canada, ⁴Stollery Children's Hospital University of Alberta, Paediatrics, Edmonton, Canada, ⁵Alberta Health Services, Biochemistry, Edmonton, Canada, ⁶Alberta Health Services, Paediatrics, Edmonton, Canada, ⁷Alberta Children's Hospital University of Calgary, Paediatrics and Community Health Sciences, Calgary, Canada, ⁸Projections Research, Phoenixville, USA

¹Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Gastrenterology and Hepatology Unit, Lisbon, Portugal

¹King's College London, London, UK, ²BRC Bioinformatics core, London, UK, ³King's College Hospital, London, UK

¹St Mark's Hospital and Academic Institute, Surgical Epidemiology Trials and Outcome Centre, London, UK, ²Imperial College London, Department of Surgery and Cancer, London, UK, ³Statsconsultancy Ltd., Buckinghamshire, UK, ⁴St Mark's Hospital and Academic Institute, London, UK, ⁵Imperial College London, Dr Foster Unit, Department of Primary Care and Public Health, London, UK

¹Medical University Vienna, Vienna, Austria, ²Yeungnam University Hospital, Daegu, South Korea, ³Clinical Hospital Center Osijek, Osijek, Croatia, ⁴Sheba Medical Center, Gastroenterology, Tel Hashomer, Israel, ⁵Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁶Pauls Stradins Clinical University Hospital, Rīga, Latvia, ⁷Novosibirsk State Medical University, Novosibirsk, Russian Federation, ⁸Private Small_Scale Enterprise Medical Centre ‘Pulse’, Vinnytsya, Ukraine, ⁹University Hospital Schleswig-Holstein, Kiel, Germany, ¹⁰Sheba Medical Center, Tel Hashomer, Israel, ¹¹Celltrion, Inc., Incheon, South Korea, ¹²Asan Medical Center, Seoul, South Korea