¹Norwegian University of Science and Technology, Department of Clinical and Molecular Medicine, Trondheim, Norway, ²Norwegian University of Science and Technology, Centre of Molecular Inflammation Research (CEMIR), Trondheim, Norway, ³St. Olav’s University Hospital, Department of Infectious Diseases, Trondheim, Norway, ⁴St. Olav’s University Hospital, Trondheim, Department of Gastroenterology and Hepatology, Trondheim, Norway, ⁵St. Olav’s University Hospital, Trondheim, Clinic of Medicine, Trondheim, Norway, ⁶University of Oslo, K.G Jebsen Inflammation Research Center, Oslo, Norway, ⁷Oslo University Hospital Rikshospitalet and Univesity of Oslo, Department of Immunology, Oslo, Norway, ⁸Nordland Hospital, Research Laboratory, Bodø, Norway, ⁹University of Tromsø, K.G. Jebsen Thrombosis Research and Expertise Center, Institute of Clinical Medicine, Tromsø, Norway

¹Centre for Molecular Medicine and Stem Cell research, Faculty of Medical Sciences University of Kragujevac Serbia, Department of Microbiology and Immunology, Kragujevac, Serbia, ²Faculty of Medical Sciences, University of Kragujevac Serbia, Department of Dentistry, Kragujevac, Serbia, ³Faculty of Medical Sciences, University of Kragujevac Serbia, Department of Psychology, Kragujevac, Serbia

¹Erasmus MC, Laboratory of Pediatrics, division Gastroenterology and Nutrition, Rotterdam, The Netherlands, ²INSERM, Institut Imagine and Université Paris-Descartes, Laboratory of Intestinal Immunity, Paris, France, ³Poznan University of Medical Sciences, Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan, Poland, ⁴Leiden University Medical Center (LUMC), Department of Paediatric Gastroenterology, Leiden, The Netherlands, ⁵Erasmus Medical Center Children's Hospital, Department of Paediatric Gastroenterology, Rotterdam, The Netherlands

¹Hospital of the Ludwig Maximilian Universität, General-, Visceral and Transplantation surgery, Munich, Germany, ²Ludwig Maximilian Universität, Institute of Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, Munich, Germany, ³Austrian Institute of Technology, Vienna, Austria, ⁴Hospital of the Ludwig Maximilian Universität, Medicine II-Grosshadern, Munich, Germany

¹Kyungpook National University School of Medicine, Internal Medicine, Daegu, South Korea, ²Yeungnam University College of Pharmacy, Pharmacy, Daegu, South Korea, ³Hanyang University College of Pharmacy, Pharmacy, Ansan, South Korea

First Affiliated Hospital of Nanjing Medical University, Department of Gastroenterology, Nanjing, China

¹Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham UK, Nottingham, UK, ²National Institute of Health Research (NIHR) Biomedical Research Centre in Gastrointestinal and Liver Diseases at Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK, ³Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham UK, Nottingham, UK, ⁴Centre for Medical Imaging, Division of Medicine, UCL UK, London, UK

¹University of Palermo, Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Palermo, Italy, ²University of Palermo, Advanced Technologies Network (ATeN) Center, Palermo, Italy, ³University of Palermo, Palermo, Italy, ⁴Institute of Biomedicine and Molecular Immunology "Alberto Monroy" (IBIM), Consiglio Nazionale delle Ricerche (CNR), Palermo, Italy

¹University of Padova, Department of Surgery, Oncology and Gastroenterology, Padova, Italy, ²IRCCS IOV Istituto Oncologico Veneto, Padova, Italy, ³Azienda Ospedaliera - Università di Padova, Padova, Italy, ⁴University of Padova, Department of Medicine, Padova, Italy, ⁵University of Padova, Department of Molecular Medicine, Padova, Italy

University Medical Center of Groningen, Groningen, The Netherlands

¹Tokyo Medical and Dental University, Gastroenterology and Hepatology, Tokyo, Japan, ²Tokyo Medical and Dental University, Center for Stem Cell and Regenerative Medicine, Tokyo, Japan, ³Tokyo Medical and Dental University, Advanced Therapeutics for Gastrointestinal Diseases, Tokyo, Japan

¹University of Leuven, Department of Human Genetics, Laboratory for Complex Genetics, Leuven, Belgium, ²University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ³University of Leuven, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), Leuven, Belgium, ⁴University of Leuven, Department of Human Genetics, Leuven, Belgium, ⁵University Hospitals Leuven, Genomics Core, Leuven, Belgium, ⁶University Hospital Ghent, Department of Gastroenterology, Ghent, Belgium, ⁷University Hospital Brussels, Department of Gastroenterology, Brussels, Belgium

¹Blizard Institute, Barts and the London School of Medicine and Dentistry, Centre for Immunobiology, London, UK, ²Barts Health, London, UK, ³Instituto de Estudios Inmunológicos y Fisiopatológicos-IIFP-CONICET-Universidad Nacional de La Plata, La Plata, Argentina

¹Hospital Universitario de La Princesa, Gastroenterology Unit, Madrid, Spain, ²Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain, ³Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain, ⁴Hospital Universitario de La Princesa, Immunology Unit, Madrid, Spain, ⁵Universidad Autónoma de Madrid, Madrid, Spain, ⁶Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), Department of Microbiology and Biochemistry of Dairy Products, Villaviciosa, Spain

¹Jawaharlal Nehru University, School of Life Sciences, New Delhi, India, ²All India Institute of Medical Sciences, Department of Gastroenterology, New Delhi, India

¹Charite - University Hospital Berlin, Department of Surgery, Berlin, Germany, ²Charité university medicine, Pathology, Berlin, Germany, ³Charité university medicine, Gastroenterology, Berlin, Germany, ⁴Charité - University Hospital Berlin, Campus Benjamin Franklin, Department of Gastroenterology and Medicine I, Berlin, Germany, ⁵Charité university medicine, Institute of Molecular Pathology, Berlin, Germany, ⁶DRK Klinikum, Department of General and Visceral Surgery, Bremen, Germany

¹Thuringia Clinic, Department of Medicine, Saalfeld, Germany, ²University Erlangen-Nuremberg, Department of Medicine, Erlangen, Germany, ³University Erlangen-Nuremberg, Department of Medicine, Erlangen, Ghana, ⁴University Cracow, Department of Physiology, Cracow, Poland

¹Erasmus MC, Laboratory of Pediatrics, division Gastroenterology and Nutrition, Rotterdam, The Netherlands, ²Erasmus MC, Department of Pulmonology, Rotterdam, The Netherlands, ³Erasmus MC, Department of Hematology, Rotterdam, The Netherlands, ⁴Erasmus Medical Center Children's Hospital, Department of Paediatric Gastroenterology, Rotterdam, The Netherlands

¹Università del Piemonte Orientale, Dipartimento di Scienze del Farmaco, Novara, Italy, ²University of Piemonte Orientale, Novara, Italy, ³University of Torino, Torino, Italy

¹Hospital General Universitario Gregorio Marañón, Servicio de Aparato Digestivo, Madrid, España, Gastroenterology Unit, Madrid, Spain, ²Hospital General Universitario Gregorio Marañón, Servicio de Aparato Digestivo, Madrid, España, Pathology, Madrid, Spain