¹Department of Public Health and Clinical Medicine- Umeå University, Medicine, Umeå, Sweden, ²Region Västernorrland, Medicine, Sundsvall, Sweden, ³Department of Public Health and Clinical medicine- Umeå University, Reumatology and Medicine, Umeå, Sweden

Samsung Medical Center, Internal Medicine Gastroenterology and Hepatology, Seoul, Republic of Korea

¹Inflammatory Bowel Disease Unit, Department of Clinical and Experimental Medicine, University of Messina, A.O.U. Policlinico ‘G. Martino’, Messina, Italy, ²Department of Economics, Unit of Statistical and Mathematical Sciences, University of Messina, Italy, ³A.O.O.R. ‘Villa Sofia-Cervello’, Inflammatory Bowel Disease Unit, Palermo, Italy, ⁴Gastroenterology and Hepatology Unit, A.O.U. Policlinico ‘G. Giaccone’,, University of Palermo, , Palermo, Italy, ⁵A.O Cannizzaro, Inflammatory Bowel Disease Unit, Catania, Italy, ⁶A.O. ‘Santa Marta e S. Venera’, Gastroenterology Unit, Acireale, Italy, ⁷A.O.O.R. ‘S. Elia- M. Raimondi’, Gastroenterology Unit, Caltanissetta, Italy

¹The Schneider Children’s Hospital, Petach-Tikva, Israel, The institute of Gastroenterology- Nutrition and Liver diseases, Petach Tikva, Israel, ²Shaare Zedek Medical Center- The Hebrew University, Jerusalem, Israel, The Juliet Keidan institute of Pediatric Gastroenterology, Jerusalem, Israel, ³Shamir Assaf Harofeh Medical Center, Pediatric Gastroenterology Unit, Zerifin, Israel, ⁴Edmond and Lily Safra Children’s Hospital, Pediatric Gastroenterology Unit, Ranat Gan, Israel, ⁵Dana-Dwek Children’s Hospital, Tel Aviv Sourasky Medical Center, Pediatric Gastroenterology Unit, Tel Aviv, Israel, ⁶Kaplan Medical Center, Pediatric Gastroenterology Unit, Rehovot, Israel, ⁷Rambam Medical Center, Pediatric Gastroenterology Unit, Haifa, Israel, ⁸Sheba Medical Center, Department of Gastroenterology, Ramat Gan, Israel

¹Gastroenterology, Henri Mondor Hospital, Creteil, France, ²Gastroenterology, Cochin Hospital, Paris, France, ³Gastroenterology, Nice University Hospital, Nice, France, ⁴Gastroenterology, Reims University Hospital, Reims, France, ⁵Gastroenterology, Bordeaux University Hospital, Bordeaux, France, ⁶Gastroenterology, Marseille University Hospital, Marseille, France, ⁷Gastroenterology, Montpellier University Hospital, Montpellier, France, ⁸Gastroenterology, Beaujon Hospital, Clichy, France, ⁹Gastroenterology, Nancy University Hospital, Nancy, France, ¹⁰Gastroenterology, Toulouse University Hospital, Toulouse, France, ¹¹Gastroenterology, St Etienne, St Etienne, France, ¹²Gastroenterology, Besancon University Hospital, Besancon, France, ¹³Gastroenterology, St Antoine Hospital, Paris, France, ¹⁴Gastroenterology, Lyon University Hospital, Lyon, France, ¹⁵Gastroenterology, St Louis Hospital, Paris, France, ¹⁶Gastroenterology, Montfermeil Hospital, Montfermeil, France, ¹⁷Gastroenterology, Rennes University Hospital, Rennes, France, ¹⁸Gastroenterology, Caen University Hospital, Caen, France, ¹⁹Gastroenterology, Lille, Lille, France, ²⁰Department of Gastroenterology and Hepatology, Amiens University Hospital, Amiens Cedex 1, France

¹Beaujon Hospital, Colorectal Surgery, Clichy, France, ²Ospedale Policlinico di Sant’Orsola-Malpighi, Digestive Surgery, Bologna, Italy, ³APHP Beaujon, Department of Colorectal Surgery, Clichy, France

¹Department of Gastroenterology, St James’s Hospital, Dublin, Ireland, ²Gastroenterology, Tallaght University Hospital, Dublin, Ireland, ³Gastroenterology, St Vincent’s University Hospital, Dublin, Ireland, ⁴Department of Biochemistry, St James’s Hospital, Dublin, Ireland

¹Department of Gastroenterology and Hepatology- C2-112- Inflammatory Bowel Disease Center, Academic Medical Center AMC University of Amsterdam, Amsterdam, The Netherlands, ²Université de Nice-Sophia Antipolis- Hôpital de l’Archet, Faculté de Médecine, Nice, France, ³Department of Medicine- Division of Gastroenterology, University of Michigan, Ann Arbor, USA, ⁴Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, USA, ⁵AbbVie Inc., Global Pharmaceutical Research and Development, North Chicago, USA, ⁶AbbVie Inc., Data and Statistical Sciences, North Chicago, USA, ⁷Humanitas Clinico Research Centre, IBD Centre, Milan, Italy

¹Guy’s & St Thomas’ NHS Foundation Trust, Gastroenterology, London, UK, ²Guy’s & St Thomas’ NHS Foundation Trust, Viapath Laboratories, London, UK

¹Department of Gastroenterology, Sheba Medical Center- Tel Hashomer, Ramat gan, Israel, ²Tel-Aviv University, Sackler School of Medicine, Tel Aviv, Israel, ³Department of Epidemiology and Preventive Medicine, School of Public Health, Tel Aviv, Israel, ⁴Department of Pediatric Gastroenterology, Sheba Medical Center- Tel Hashomer, Ramat gan, Israel

¹Gastroenterology, Mount Sinai Hospital, Toronto, Canada, ²General Surgery, Mount Sinai Hospital, Toronto, Canada, ³Centre for Global and Public Health, University of Manitoba, Winnepeg, Canada

¹Gastroenterologische Gemeinschaftspraxis Minden and University Hospital Schleswig-Holstein, Campus Kiel, Clinic for Internal Medicine I, Gastroenterology Practice, Minden, Germany, ²Competence-net IBD Germany, Study Department, Kiel, Germany, ³Competence-net IBD, Statistic Department, Kiel, Germany, ⁴Gastroenterology Practice Saarbrücken, Gastroenterology, Saarbrücken, Germany, ⁵Gastroenterology Practice Iserlohn, Gastroenterology, Iserlohn, Germany, ⁶Gastroentrology Practice Kassel, Gastroenterology, Kassel, Germany, ⁷University Hospital Erlangen, Gastroenterology Department, Erlangen, Germany, ⁸Gastroenterology Practice Herne, Gastroenterology, Herne, Germany, ⁹Gastroenterology Practice Berlin, Gastroenterology, Berlin, Germany, ¹⁰Gastroenterogy Practice Bremen, Gastroenterology, Bremen, Germany, ¹¹Gastroenterology Practice Mössingen, Gastroenterology, Mössingen, Germany, ¹³Competence-net IBD, Study Department, Kiel, Germany, ¹⁴Gastroenterology Practice Minden, Study Nurse, Minden, Germany, ¹⁵University Hospital Schleswig-Holstein- Campus Kiel- Clinic for Internal Medicine I, Gastroenterology Department, Kiel, Germany

Hospital Alemán, Department of Gastroenterology, Caba, Buenos Aires, Argentina

¹Aristotle University of Thessaloniki, Clinical research and Evidence-Based Medicine Unit, Thessaloniki, Greece, ²University of Oxford, Harris Manchester College, Oxford, UK

¹Gastroenterology, New York University School of Medicine, New York, USA, ²Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, USA, ³Gastroenterology, Weill Medical College of Cornell University, New York, USA, ⁴Gastroenterology, Albert Einstein College of Medicine, New York, USA, ⁵Gastroenterology, Hofstra Northwell School of Medicine, New York, USA, ⁶Columbia University Medical Center, Digestive and Liver Diseases, New York, USA, ⁷Gastroenterology, University of North Carolina School of Medicine, Chapel Hill, USA

¹CHU Amiens Sud, Service d’hepato-gastroentérologie, Amiens, France, ²APHM Hopital Nord, Hepato-gastroenterologie, Marseille, France, ³Hopital Haut Leveque, Hépato-gastroentérologie, Bordeaux, France, ⁴CHU Pontchaillou, Gastroenterologie, Rennes, France, ⁵Hopital Claude huriez, Gastroentérologie, Lille, France, ⁶Hôpital Saint Eloi, Gastroentérologie, Montpellier, France, ⁷Hopital Charles Nicolle, Gastroentérologie, Rouen, France, ⁸Hopital de l’Archet, Gastroentérologie, Nice, France, ⁹Policlinique Saint Claude, Gastroentérologie, Saint Quentin, France, ¹⁰Hopital universitaire, Gastroentérologie, Clermont Ferrand, France, ¹¹Hopital universitaire, Gastroentérologie, Besançon, France, ¹²CHU Amiens Sud, Statistique, Amiens, France

Royal Surrey NHS Foundation Trust, Department of Gastroenterology, Guildford, UK

¹Kyushu University, Department of Medicine and Clinical Science, Fukuoka, Japan, ²Kyushu University, Department of Epidemiology and Public Health, Fukuoka, Japan, ³Saga University Hospital, Department of Endoscopic Diagnostics and Therapeutics, Saga, Japan

¹Department of Gastroenterology, Yildirim Beyazit University Ankara, Turkey, ²Deparment of Gastroenterology, Ankara Sehir Hospital, Ankara, Turkey, ³Department of Gastroenterology, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey

¹Hospital Senhora da Oliveira, Gastroenterology, Guimarães, Portugal, ²Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga/Guimarães, Portugal, ³ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal