¹CHU Estaing, Department of Digestive and Hepatobiliary Medicine, Department of Gastroenterology, Clermont-Ferrand, France, ²CHU Amiens, Gastroenterology, Amiens, France, ³CHU Marseille, Gastroenterology, Marseille, France, ⁴CHU Lyon-Sud, Gastroenterology, Lyon, France, ⁵CHU Bordeaux, Gastroenterology, Bordeaux, France, ⁶CHU Montpellier, Gastroenterology, Montpellier, France, ⁷CHU Nancy, Gastroenterology, Nancy, France, ⁸CHU Lille, Gastroenterology, Lille, France, ⁹CHU Nice, Gastroenterology, Nice, France, ¹⁰CHU Toulouse, Gastroenterology, Toulouse, France, ¹¹Private practice, Gastroenterology, Nantes, France, ¹²CHU Caen, Gastroenterology, Caen, France, ¹³CHU Rennes, Gastroenterology, Rennes, France, ¹⁴CHU Créteil, Gastroenterology, Créteil, France, ¹⁵Private practice- Pole Sante Republique ELSAN, Gastroenterology, Clermont-ferrand, France, ¹⁶CHU Besançon, Gastroenterology, Besançon, France, ¹⁷CH Colmar, Gastroenterology, Clermont-Ferrand, France, ¹⁸CHU Nantes, Gastroenterology, Nantes, France, ¹⁹CHU Nîmes, Gastroenterology, Nîmes, France, ²⁰CH Bayonne, Gastroenterology, Bayonne, France, ²¹Private practice, Gastroenterology, Amiens, France, ²²Private practice, Gastroenterology, Paris, France, ²³CHU St Etienne, Gastroenterology, St-Etienne, France, ²⁴CHU, Biostatistics unit, Clermont-Ferrand, France

Department of Public Health and Clinical Medicine, Umeå University, Medicine, Umeå, Sweden

¹First Department of Medicine, University of Szeged, Szeged, Hungary, ²Physiological Controls Research Center, Óbuda University,Budapest, Hungary, ³Department of Laboratory Medicine, University of Szeged, Szeged, Hungary

¹Department of Gastroenterology, Dayanand Medical College and Hospital - Ludhiana, Ludhiana, India, ²Department of Medicine, Dayanand Medical College and Hospital - Ludhiana, Ludhiana, India, ³Research and Development Centre, Dayanand Medical College and Hospital - Ludhiana, Ludhiana, India, ⁴Department of Pharmacology, Dayanand Medical College and Hospital - Ludhiana, Ludhiana, India

¹Department of Gastroenterology, Erasmus MC, Rotterdam, The Netherlands, ²Department of Surgery, IJsselland Hospital, Capelle a/d IJssel, The Netherlands, ³Department of Radiology, Erasmus MC, Rotterdam, The Netherlands

¹Fondazione IRCCS Cà Granda- Ospedale Policlinico di Milano, Gastroenterology and Endoscopy Unit, Milan, Italy, ²ASST Bergamo Est – Ospedale di Seriate, Unità Operativa di Gastroenterologia, Seriate, Italy, ³ASST degli Spedali Civili di Brescia, Unità Operativa di Gastroenterologia, Brescia, Italy, ⁴ASST Monza − Ospedale San Gerardo di Monza, Unità Operativa di Gastroenterologia, Monza, Italy, ⁵ASST Valle Olona – Ospedale di Busto Arsizio, Unità Operativa di Medicina I, Busto Arsizio, Italy, ⁶ASST Crema – Ospedale Maggiore di Crema, Unità Operativa di Gastroenterologia, Crema, Italy, ⁷Policlinico San Donato, Unità Operativa di Gastroenterologia, San Donato Milanese, Italy, ⁸ASST Valle Olona – Ospedale di Gallarate, Unità Operativa di Gastroenterologia, Gallarate, Italy, ⁹Ospedale Valduce di Como, Unità Operativa di Gastroenterologia, Como, Italy, ¹⁰University of Milan, Department of Pathophysiology and Transplantation, Milan, Italy, ¹¹Istituto Clinico Humanitas, IBD Center, Rozzano, Italy

¹Gastroenterology and Liver Services, Concord Repatriation General Hospital, Sydney, Australia, ²Concord Clinical School, University of Sydney, Sydney, Australia

¹Department of Gastroenterology, Hôpital Erasme, Brussels, Belgium, ²Department of Gastroenterology, Imelda General Hospital, Bonheiden, Belgium, ³Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium, ⁴Department of Gastroenterology, CHU UCL Namur, Yvoir, Belgium, ⁵Department of Gastroenterology, Centre Hospitalier Universitaire Sart-Tilman, Liège, Belgium, ⁶Department of Gastroenterology, AZ Delta, Roeselare, Belgium, ⁷Department of Gastroenterology, AZ Maria Middelares, Gent, Belgium, ⁸Department of Gastroenterology, UZ Antwerp, Antwerp, Belgium, ⁹Department of Gastroenterology, AZ Damian, Oostende, Belgium, ¹⁰Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium

¹Department of Medicine I, Agaplesion Markus Hospital, Goethe-University, Frankfurt, Germany, ²Department of Gastroenterology, Infectious Diseases, Rheumatology, Charité -Universitätsmedizin, Berlin, Germany

¹Institute for Maternal Health - IRCCS ‘Burlo Garofolo’, Advanced in Translational Diagnostics Laboratory, Trieste, Italy, ²Institute for Maternal Health - IRCCS ‘Burlo Garofolo’, Gastroenterology- Digestive Endoscopy and Clinical Nutrition Unit, Trieste, Italy, ³Department of Medical-Surgical and Health Sciences, PhD School in Science of Reproduction and Development- University of Trieste- Trieste- Italy, Trieste, Italy, ⁴Department of Life Sciences, University of Trieste - Trieste - Italy, Trieste, Italy, ⁵Gastroenterology Unit, Anna Meyer Children’s Hospital -Florence- Italy, Florence, Italy, ⁶Department of Medical-Surgical and Health Sciences, PhD School in Science of Reproduction and Development, University of Trieste - Trieste - Italy, Trieste, Italy, ⁷Department of Medical-Surgical and Health Sciences, University of Trieste - Trieste - Italy, Trieste, Italy

¹Department of Paediatrics, 2nd Faculty of Medicine- Charles University and Motol University Hospital, Prague, Czech Republic, ²Department of Probability and Mathematical Statistics, School of Mathematics- Charles University, Prague, Czech Republic, ³Pediatric Institute-Clinic, University of Debrecen, Debrecen, Hungary, ⁴Department of Paediatrics, Hospital de Sao Joao, Porto, Portugal, ⁵Department of Pediatrics- Gastroenterology and Nutrition, Polish-American Children’s Hospital- Jagiellonian University Medical College, Cracow, Poland, ⁶Department of Paediatrics, Children’s Hospital Zagreb Faculty of Medicine, Zagreb, Croatia, ⁷Department of Pediatrics and Medical Genetics, Ghent University- Ghent University Hospital, Ghent, Belgium, ⁸Department of Paediatrics, Charles University Teaching Hospital, Hradec Kralove, Czech Republic, ⁹Department of Gastroenterology, 2nd Clinic of Pediatrics- ‘Iuliu Hatieganu’ University of Medicine and Pharmacy- Emergency Clinical Hospital for Children, Cluj-Napoca, Romania, ¹⁰Department of Paediatrics, Hvidovre Hospital, Copenhagen, Denmark, ¹¹Department of Paediatrics, Amsterdam UMC- Location VUMC, Amsterdam, The Netherlands, ¹²Department of Paediatrics, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic, ¹³Department of Gastroenterology, Children’s Hospital and University of Helsinki, Helsinki, Finland, ¹⁴Department of Gastroenterology, Erasmus MC−Sophia Children’s Hospital, Rotterdam, The Netherlands

¹Icahn School of Medicine at Mount Sinai, New York, New York, USA, ²New York University, New York, New York, USA, ³Unit of Inflammatory Bowel Disease, Hospital Israelita Albert Einstein, São Paulo, Brazil, ⁴Pfizer Inc., Collegeville, Pennsylvania, USA, ⁵Syneos Health, Morrisville, North Carolina, USA, ⁶Pfizer Inc., Lima, Peru, Peru, ⁷University of Porto and Centro Hospitalar São João, Porto, Portugal, Portugal

Policlinico Sant’Orsola Malpighi, Malattie Infiammatorie Croniche Prof. Gionchetti, Bologna, Italy

¹ISCARE I.V.F. a.s., IBD Clinical and Research Centre, Prague, Czech Republic, ²Institute of Medical Biochemistry and Laboratory Medicine, General University Hospital and First Faculty of Medicine-Charles University, Prague, Czech Republic, ³Institute of Pharmacology, First Faculty of Medicine, Charles University, Prague, Czech Republic, ⁴Department of Internal Medicine, First Faculty of Medicine, Charles University and Military University Hospital, Prague, Czech Republic

Department of Gastroenterology and Hepatology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia

¹Department of Pediatric Gastroenterology and Nutrition, Shaare Zedek Medical Center, Jerusalem, Israel, ²Department of paediatric gastroenterology, Hôpitaux de Paris, Paris, France, ³Department of Paediatric Gastroenterology, Ljubljana University Medical Centre, Ljubljana, Slovenia, ⁴Emergency Clinical Hospital for Children, 2nd Clinic of Pediatrics, Cluj-Napoca, Romania, ⁵Department of Paediatric Gastroenterology, Erasmus MC/Sophia Children′s Hospital, Rotterdam, The Netherlands, ⁶Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy, ⁷Department of Paediatric Gastroenterology, University of Messina, Messina, Italy, ⁸Department of Paediatric Gastroenterology, Sapienza University of Rome, Rome, Italy, ⁹Department of Paediatric Gastroenterology, Sheffield Children’s Hospital, Sheffield, UK

¹Gastroenterology Department- IBD Unit, Hospital de Galdakao, Galdakao, Spain, ²Gastroenterology Department- IBD Unit, Hospital Ramón y Cajal, Madrid, Spain, ³Gastroenterology Department, Hospital Clínico San Carlos, Madrid, Spain, ⁴Spanish Confederation of Associations Of Patients with Crohn’s Disease and Ulcerative Colitis ACCU, ACCU, Madrid, Spain, ⁵Medical Affairs Department, Merck Sharp and Dohme of Spain, Madrid, Spain

¹Galapagos NV, Clinical Development, Mechelen, Belgium, ²Division of Immunology and Rheumatology, Stanford University, Palo Alto, CA, USA, ³Department of Rheumatology, Universitair Ziekenhuis Leuven, Leuven, Belgium, ⁴Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France, ⁵Division of Rheumatology- Allergy and Immunology, University of California, San Diego, CA, USA, ⁶Medical Affairs, Gilead Sciences Inc., Foster City, CA, USA, ⁷Clinical Development, Gilead Sciences Inc., Foster City, CA, USA, ⁸Biostatistics, Gilead Sciences Inc., Foster City, CA, USA, ⁹Clinical Research, Gilead Sciences Inc., Foster City, CA, USA, ¹⁰Department of Rheumatology, Northumbria Healthcare, Northumbria, UK, ¹¹Division of Rheumatology and Clinical Immunology, Keio University School of Medicine, Tokyo, Japan

¹Clinical and Research Center for Inflammatory Bowel Disease, ISCARE a.s. and Charles University, Prague 7, Czech Republic, ²Institute of Medical Biochemistry and Lab Diagnostics, General University Hospital and 1st Faculty of Medicine, Prague, Czech Republic, ³Institute of Pharmacology, First Faculty of Medicine of Charles University, Prague, Czech Republic, ⁴Department of Internal Medicine, Military University Hospital and 1st Faculty of Medicine of Charles University, Prague, Czech Republic, ⁵Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Libechov, Czech Republic, ⁶Department of Pediatry, University Hospital Motol and 2nd Faculty of Medicine of Charles University, Prague, Czech Republic, ⁷Department of Internal Medicine, Hospital of the Sisters of Mercy of St. Borromeo, Prague, Czech Republic

Department of Colorectal Surgery, St. Mark’s Hospital, Harrow, UK