¹Inflammatory Bowel Disease Unit, Department of Clinical and Experimental Medicine, University of Messina, A.O.U. Policlinico ‘G. Martino’, Messina, Italy, ²Department of Economics, University of Messina, Messina, Italy

Royal Wolverhampton NHS Trust, Colorectal Surgery, Wolverhampton, UK

¹Asan Medical Center, University of Ulsan College of Medicine, Department of Gastroenterology, Seoul, Korea Republic of, ²Asan Medical Center, University of Ulsan College of Medicine, Inflammatory Bowel Disease Center, Seoul, Korea Republic of, ³Asan Medical Center, University of Ulsan College of Medicine, Department of Clinical Epidemiology and Biostatistics, Seoul, Korea Republic of, ⁴Asan Medical Center, University of Ulsan College of Medicine, Department of Gastroenterology and Inflammatory Bowel Disease Center, Seoul, Korea Republic of

¹Nova Scotia Health Authority, Digestive Care and Endoscopy, Halifax, Canada, ²Dalhousie University, Medicine, Halifax, Canada

¹School of Pharmaceutical Sciences, Sun Yat-Sen Unversity, Guangzhou, China, ²Department of Gastroenterology, the Sixth Affiliated Hospital- Sun Yat-sen University, Guangzhou, China

¹Leiden University Medical Center, Department of Gastroenterology and Hepatology, Leiden, The Netherlands, ²Radboud University Medical Centre, Department of Gastroenterology and Hepatology, Nijmegen, The Netherlands, ³Maastricht University Medical Centre, Department of Gastroenterology and Hepatology, Maastricht, The Netherlands, ⁴University Medical Centre Groningen, Department of Gastroenterology and Hepatology, Groningen, The Netherlands, ⁵Amsterdam University Medical Centre- Academic Medical Centre, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁶Haaglanden Medical Centre, Department of Gastroenterology and Hepatology, Den Haag, The Netherlands, ⁷Amsterdam University Medical Centre- Vrije Universiteit Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁸Amphia Hospital, Department of Gastroenterology and Hepatology, Breda, The Netherlands, ⁹Onze Lieve Vrouwe Gasthuis, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands, ¹⁰Franciscus Gasthuis and Vlietland, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands

¹Department of Data Analytics and Design Strategy, RTI Health Solutions, Manchester, UK, ²Outcomes Research and Epidemiology, Shire - a Takeda Company, Health Economics, Lexington, USA, ³School of Pharmacy, University of Washington, Seattle, USA, ⁴Dr Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai Medical Center, New York, USA, ⁵Division of Gastroenterology, University of Calgary, Calgary, Canada, ⁶Department of Gastroenterology, University Hospital of Nancy-Brabois, Vandœuvre-lès-Nancy, France, ⁷IBD Center, Humanitas University, Milan, Italy, ⁸Department of Gastroenterology, University Hospital Leuven, Leuven, Belgium, ⁹Zymo Consulting Group, Clinical Development, Newtown Square, USA, Clinical Development, ¹⁰Shire - a Takeda compa#ny, Zug, Switzerland

¹Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA, ²Pfizer Inc., Groton, CT, USA, ³Pfizer Inc., Collegeville, PA, USA, ⁴University of the State of Bahia, Salvador, Bahia, Brazil, ⁵Pfizer Inc., Lima, Peru, Peru, ⁶McGill University Health Center, Montreal, Québec, Canada

Department of Gastroenterology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey

¹Department of Gastroenterology, University Hospital Ghent, Ghent, Belgium, ²VIB Center for Inflammation Research, Ghent University, Ghent, Belgium, ³IBD Research Unit, Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium

¹St. Mark’s Hospital, Department of Colorectal Surgery, Harrow, UK, ²Imperial College London, Computational Systems Division, London, UK, ³Queen Mary University of London, Department of Surgery, London, UK, ⁴The Blizard Institute- Queen Mary University of London, Department of Surgery, London, UK

¹Department of Gastroenterology, Hôpital Erasme, Brussels, Belgium, ²Laboratory of Experimental Gastroenterology, ULB, Brussels, Belgium, ³Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium

¹Department of Gastroenterology, La Fe University Hospital, Valencia, Spain, ²Enfermedad Inflamatoria Intestinal, Instituto de Investigación Sanitaria La Fe de Valencia IIS La Fe, Valencia, Spain, ³Department of Pharmacy, La Fe University Hospital, Valencia, Spain

¹Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea Republic of, ²Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea Republic of, ³Department of Internal Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea Republic of, ⁴Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea Republic of, ⁵Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital- Sungkyunkwan University School of Medicine, Seoul, Korea Republic of, ⁶Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea Republic of, ⁷Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea Republic of, ⁸Division of Gastroenterology, Department of Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea Republic of, ⁹Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea Republic of, ¹⁰Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea Republic of, ¹¹Division of Gastroenterology, Department of Internal Medicine, Daejeon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Korea Republic of, ¹²Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea Republic of, ¹³Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea Republic of, ¹⁴Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea Republic of, ¹⁵Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea Republic of, ¹⁶Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea Republic of

¹Gastroenterology Department, San Juan de Dios Hospital, IBD Fellow Clínica Las Condes, Santiago, Chile, ²Clínica Las Condes, Gastroenterology Department, Inflammatory Bowel Disease Program, Santiago, Chile, ³Clínica Las Condes, Surgery Department, Colorectal Unit, Inflammatory Bowel Disease Program, Santiago, Chile

¹Hamilton Health Sciences, Ambulatory Care Program, Hamilton, Canada, ²College of Medicine and Health, University College Cork, Cork, Ireland, ³Division of Gastroenterology, Department of Medicine, McMaster University, Hamilton, Canada, ⁴School of Nursing, McMaster University, Hamilton, Canada

¹Department of Gastroenterology, Centro Hospitalar Universitário do Porto, Porto, Portugal, ²Instituto Ciencias Biomédicas Abel Salazar, University of Porto, Porto, Portugal, Department of General Surgery, ³Centro Hospitalar Universitário do Porto, Porto, Portugal

¹Department of Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, ²Department of Gastroenterology, Kagoshima City Hospital, Kagoshima, Japan, ³Department of Gastroenterology, Sameshima Hospital, Kagoshima, Japan, ⁴Department of Gastroenterology, Idzuro Imamura Hospital, Kagoshima, Japan, ⁵Department of Gastroenterology, Kagoshima Kouseiren Hospital, Kagoshima, Japan

Department of Gastroenterology, Salford Royal Foundation Trust, Manchester, UK

¹Department of Medicine, University of Calgary, Calgary, Canada, ²Faculty of Health Disciplines, Athabasca University, Athabasca, Canada, ³N/A, KAL Research and Consulting, Denver, USA, ⁴University of Calgary, Calgary, Canada, ⁵University of Calgary, Snyder, Calgary, Canada, ⁶University of Calgary, Department of Kinesiology, Calgary, Canada