¹Department of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, USA, ²Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, USA, ³Department of Gastroenterology, Takeda Pharmaceuticals, Deerfield, USA, ⁴Lilly Biomedicines, Eli Lilly & Company, Indianapolis, USA, ⁵Department of Gastroenterology, Mount Sinai, New York, USA

¹Division of Gastroenterology and Hepatology, Maastricht Universitair Medisch Centrum+, Pacmed, Maastricht, The Netherlands, ²Division of Gastroenterology and Hepatology, Maastricht Universitair Medisch Centrum+, Maastricht, The Netherlands, ³Haga Ziekenhuis, Department of Gastroenterology, Den Haag, The Netherlands, ⁴Department of Gastroenterology, Leiden University Medical Center, Leiden, The Netherlands, ⁵Department of Gastroenterology, Zuyderland Medical Centre, Sittard, The Netherlands, ⁶Department of Gastroenterology, St. Antonius Ziekenhuis, Nieuwegein, The Netherlands, ⁷Stichting mijnIBDcoach, Board, Mijdrecht, The Netherlands, ⁸Department of Gastroenterology, Universitair Medisch Centrum Groningen, Groningen, The Netherlands, ⁹Department of Health Care, Pacmed, Amsterdam, The Netherlands, ¹⁰Information Systems, Faculty of Industrial Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands, ¹¹Department of Internal Medicine, Division of Gastroenterology-Hepatology, University Maastricht, Maastricht, The Netherlands, ¹²Department of Quantitative Economics, School of Business and Economics, Maastricht University, Maastricht, The Netherlands, ¹³Department of Data Analytics and Digitalisation, Maastricht University, Maastricht, The Netherlands

¹Department of Gastroenterology, Oslo University Hospital, Oslo, Norway, ²Department of Gastroenterology and Hepatology, Danderyds Hospital, Stockholm, Sweden, ³Department of Gastrounit- Medical Division, Hvidovre University Hospital, Hvidovre, Denmark, ⁴Department of Medical Gastroenterology, Herlev Hospital, Herlev, Denmark, ⁵Department of Medicine, Hospital South West Denmark, Department of Regional Health Research, University of Southern Denmark, Odense, Denmark, ⁶Department of Gastroenterology, University of Turku, Turku, Finland, ⁷Takeda AS, Medical Affairs, Asker, Norway, ⁸Takeda Oy, Medical Affairs, Helsinki, Finland, ⁹Department of Medical Affairs, Takeda Pharma AB, Stockholm, Sweden, ¹⁰Department of Medical Affairs, Taastrup, Denmark, ¹¹Department of Health Management and Health Economics, Institute of Health and Society, University of Oslo, Oslo, Norway

¹Department of Gastroenterology- IBD Unit, University Hospital Santiago De Compostela CHUS, Santiago De Compostela, Spain, ²Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gatroenterology, Hospital Universitario de Alicante, Alicante, Spain, ³Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Hospital Universitari Mútua Terrassa, Terrasa, Spain, ⁴Centro de de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD-, Gastroenterology, Hospital Universitario La Fe, Valencia, Spain, ⁵Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Corporació Sanitaria Universitària Parc Taulí, Sabadell, Spain, ⁶Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Hospital Universitario de La Princesa and Instituto de Investigación Sanitaria Princesa IIS-IP, Madrid, Spain, ⁷Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Germans Trias i Pujol, Badalona, Spain, ⁸Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Hospital Clinic, Gastroenterology, Barcelona, Spain

Department of General Surgery, Jinling Hospital, Nanjing, China

¹Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, USA, ²Department of Medicine, University Hospital Schleswig-Holstein, Kiel, Germany, ³Department of Gastrointestinal Immunopathology, Humanitas University, Milan, Italy, ⁴Department of Gastroenterology, Nancy University Hospital, Nancy, France, ⁵Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, USA, ⁶Global Outcomes Research and Epidemiology, Takeda, Cambridge, USA, ⁷Statistics and Quantitative Sciences, Takeda, Cambridge, USA, ⁸Clinical Science, Takeda, Cambridge, USA

¹Department of Gastroenterology, University of North Carolina, Chapel Hill, USA, ²Department of Gastroenterology, Atrium Health, Charlotte, USA, ³Department of Gastroenterology, Cleveland Clinic, Cleveland, USA, ⁴Department of Gastroenterology, University of Wisconsin, Madison, USA, ⁵Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai Medical Center, New York, USA, ⁶Department of Gastroenterology, University of Chicago, Chicago, USA, ⁷Department of Pediatric Gastroenterology and Nutrition, Mount Sinai School of Medicine, New York, USA, ⁸Department of Gastroenterology, Dartmouth Hitchcock, Lebanon, USA, ⁹Department of Statistics, TARGET PharmaSolutions, Durham, USA, ¹⁰Scientific and Medical Affairs, TARGET PharmaSolutions, Durham, USA

¹University of Helsinki and Helsinki University Hospital, Helsinki, Finland, ²Tampere University Hospital, Tampere, Finland, ³ESiOR Oy, Kuopio, Finland, ⁴Kanta-Häme Central Hospital, Hämeenlinna, Finland, ⁵North Karelia Central Hospital, Joensuu, Finland, ⁶South Karelia Central Hospital, Lappeenranta, Finland, ⁷Lapland Central Hospital, Rovaniemi, Finland, ⁸Oulu University Hospital, Oulu, Finland, ⁹Central Finland Central Hospital, Jyväskylä, Finland, ¹⁰Satakunta Central Hospital, Pori, Finland, ¹¹Vaasa Central Hospital, Vaasa, Finland, ¹²Turku University Hospital, Turku, Finland, ¹³Kuopio University Hospital, Kuopio, Finland, ¹⁴Kainuu Central Hospital, Kajaani, Finland, ¹⁵Päijät-Häme Central Hospital, Lahti, Finland, ¹⁶Turku University Hospital Salo Hospital, Salo, Finland, ¹⁷Central Ostrobothnia Central Hospital, Kokkola, Finland, ¹⁸Janssen Cilag, Medical Affairs, Solna, Sweden, ¹⁹Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark, ²⁰Janssen Cilag Limited, Emea Hemar, High Wycombe, UK, ²¹Medical Affairs, Janssen Cilag Oy, Espoo, Finland

¹Department of Surgery, Amsterdam UMC-location AMC, Amsterdam, The Netherlands, ²Department of Gastroenterology and Hepatology, Amsterdam UMC-location AMC, Amsterdam, The Netherlands

¹Exeter IBD Pharmacogenetics Research Group, University of Exeter, Exeter, UK, ²Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK, ³Translational Exchange @ Exeter- Living Systems Institute, University of Exeter, Exeter, UK, ⁴Department of Research and Development, AbbVie Inc., North Chicago, USA

¹Cedars Sinai Medical Center, Inflammatory Bowel and Immunobiology Research Institute, Los Angeles, California, USA, ²Cedars Sinai Medical Center, Department of Surgery, Los Angeles, CA, USA

¹Massachusetts General Hospital, Division of Gastroenterology, Boston, USA, ²Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, USA, ³Department of Molecular Biology, Massachusetts General Hospital, Boston, USA

¹Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium, ²Laboratory for Complex Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, ³Department of Electrical Engineering ESAT, KU Leuven, Leuven, Belgium, ⁴Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium, ⁵Department of Gastroenterology, University Hospital of Ghent, Ghent, Belgium, ⁶Department of Gastroenterology, University Hospitals Brussels, Brussels, Belgium

Janssen Research and Development- LLC, Immunology, Spring House, USA

¹Hospital of the Ludwig Maximilian Universität, General, Visceral- und Transplantation Surgery, München, Germany, ²Hospital of the Ludwig Maximilian Universität, Institute of Laboratory Medicine, München, Germany, ³Hospital of the Ludwig Maximilian Universität, Department of Medicine II, München, Germany

¹Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland, ²Department of Basic Sciences, Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel, ³Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland, ⁴Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland, ⁵Department of Obstetrics and Gynecology, Hadassah University Hospital, Jerusalem, Israel

¹APHP Saint Louis, Gastroenterology, Paris, France, ²INSERM, Unité U1160, Paris, France

¹Department of Gastroenterology, Center for Crohn’s and Colitis, Kyung Hee University College of Medicine, Seoul, Korea Republic of, ²Department of Biology, Kyung Hee University College of Sciences, Seoul, Korea Republic of

¹Department of Gastroenterology, Erasme University Hospital- ULB, Brussels, Belgium, ²Institut Jules Bordet, Department of Pathology, Brussels, Belgium, ³Department of Gastroenterology, University Hospital Ghent, Ghent, Belgium, ⁴Department of Gastroenterology, CHU UCL Namur, Yvoir, Belgium, ⁵Department of Gastroenterology, AZ Delta, Roeselare, Belgium, ⁶Department of Gastroenterology, University Hospital Antwerp, Edegem, Belgium, ⁷Department of Gastroenterology, University Hospital Liège, Liège, Belgium, ⁸Department of Gastroenterology, University Hospital Leuven, Leuven, Belgium

¹Department of Gastroenterology, Hopital Erasme, Brussels, Belgium, ²Laboratory of Experimental Gastroenterology, ULB, Brussels, Belgium