¹Laboratory of Clinical immunology, University hospital St. Ivan Rilski, Medical university of Sofia, Sofia, Bulgaria, ²Clinic of gastroenterology, University hospital ‘St. Ivan Rilski’, Department of Internal medicine, Medical University of Sofia, Bulgaria, Sofia, Bulgaria

¹Translational Gastroenterology Unit, Gastroenterology, Oxford, UK, ²Clatterbridge Cancer Centre, Oncology, Liverpool, UK, ³Royal Liverpool University Hospital, Gastroenterology, Liverpool, UK, ⁴Churchill Hospital, Oncology, Oxford, UK

¹Tokyo Medical and Dental University, Gastroenterology and Hepatology, Tokyo, Japan, ²Tokyo Medical and Dental University, Radiology, Tokyo, Japan

¹University of São Paulo Medical School, Department of Gastroenterology and Hepatology, São Paulo, Brazil, ²University of São Paulo Medical School, Cardiovascular Magnetic Resonance and Computed Tomography Sector, Heart Institute, InCor, São Paulo, Brazil

¹Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, ²Clinical Hospital Centre Zagreb, Gastroenterology and Hepatology, Zagreb, Croatia

¹Hospital da Senhora da Oliveira, Gastroenterology, Guimarães, Portugal, ²Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga/Guimarães, Portugal, ³ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal

¹John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, UK

¹Gastroenterology, School of Medicine Federico II of Naples, Naples, Italy, ²Pediatrics, School of Medicine Federico II of Naples, Naples, Italy

¹Kyorin University School of Medicine, Tokyo, Japan, ²Kyorin University School of Medicine, The Third Department of Internal Medicine, Tokyo, Japan, ³Kyorin University Hospital, Central Clinical Laboratory, Tokyo, Japan, ⁴Kyorin University School of Medicine, Department of Laboratory Medicine, Tokyo, Japan

¹Hospital Sant Joan de Déu, Unit for Comprehensive Care of Pediatric Inflammatory Bowel Disease. Pediatric Gasatroneterology, Hepatology and Nutrition Unit, Barcelona, Spain

¹Department of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Pathology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ³Department of Endoscopy, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

¹Tokyo Women's Medical University, Institute of gastroenterology, Tokyo, Japan

¹University of Cambridge, Department of Medicine, Cambridge, UK

¹University Hospitals Leuven, Department of Paediatric gastroenterology and Hepatology and Nutrition, Leuven, Belgium, ²Catholic University of Leuven (KU Leuven), TARGID, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), Leuven, Belgium, ³University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium

¹Faculty of Medicine, University of Porto, Department of Biomedicine, Unit of Pharmacology and Therapeutics, Porto, Portugal, ²MedInUP, Centre for Drug Discovery and Innovative Medicines, University of Porto, Porto, Portugal, ³Faculty of Medicine, University of Lisbon, Instituto de Saúde Ambiental, Lisbon, Portugal, ⁴Centro Hospitalar do Porto, Gastroenterology Department, Porto, Portugal, ⁵Hospital de Braga, Gastroenterology Department, Braga, Portugal, ⁶Hospital Garcia de Orta, Department of Gastroenterology, Almada, Portugal, ⁷Faculty of Medicine, University of Porto, Health Information and Decision Sciences Department, Porto, Portugal, ⁸Center for Health Technology and Services Research, Porto, Portugal, ⁹Centro Hospitalar São João, Gastroenterology Department, Porto, Portugal

¹Hyogo College of Medicine, Division of Internal Medicine, Department of Inflammatory Bowel Disease, Nisinomiya, Hyogo, Japan, ²Hyogo College of Medicine, Division of Surgery, Department of Inflammatory Bowel Disease, Nisinomiya, Hyogo, Japan, ³Hyogo College of Medicine, Division of Gastroenterology, Department of Internal Medicine, Nisinomiya, Hyogo, Japan

¹Hospices Civils de Lyon, Gastroenterology, Pierre Benite, France, ²CHU Saint Etienne, Gastroenterology, Saint Etienne, France, ³Hospices Civils de Lyon, Biochemistry, Pierre Benite, France

¹Kyoto Prefectural University of Medicine, Molecular Gastroenterology and Hepatology, Kyoto, Japan, ²Asahi University Hospital, Department of Gastroenterology, Gifu, Japan

¹Meir Hospital, Gastroenterology and Liver disease, Kfar Saba, Israel, ²Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel

¹Worcestershire Acute Hospitals NHS Trust, Department of Colorectal Surgery, Worcester, UK, ²Worcestershire Acute Hospitals NHS Trust, Department of Radiology, Worcester, UK