P0455: An eosinophilic endotype of ulcerative colitis is linked with a more complicated disease phenotypeECCO'25Year: 2025
Authors: Jantsch, A.(1,2)*;Vorhaben, T.(1,2);Yalcin, F.(3);Hinrichsen, F.(1,4);Lebich, J.(2);Bourgery, M.(1,4);Welz, L.(1,2);Labrenz, J.(2);Lüschen, S.(3);Röcken, C.(3);Aden, K.(1,2);Rosenstiel, P.(2);Schreiber, S.(1);Tran, F.(1,2);
(1)University Hospital Schleswig-Holstein- Campus Kiel, Department of Internal Medicine I/Gastroenterology, Kiel, Germany;(2)University Hospital Schleswig-Holstein- Campus Kiel, Institute of Clinical Molecular Biology, Kiel, Germany;(3)University Hospital Schleswig-Holstein- Campus Kiel, Department of Pathology, Kiel, Germany;(4)University Hospital Schleswig-Holstein- Campus Kiel, Insitute of Clinical Molecular Biology, Kiel, Germany;
This project has received funding from the DFG Cluster of Excellence 2167 "Precision medicine in chronic inflammation", the BMBF (e:Med Network iTREAT 01ZX2202A), EKFS (2022_EKMS.23), the PATHWAYS Global Innovation Grant program (Sanofi & Regeneron), and the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 831434 (3TR) and No 853995 (ImmUniverse).The JU receives support from the European Union's Horizon 2020 research and innovation programme and EFPIA. The content provided in this publication reflects the author's views only. Neither the Innovative Medicines Initiative (IMI JU) nor the European Commission are responsible for any use that may be made of the information it contains.
P0456: Peripheral blood eosinophilia: A novel predictor of disease severity in Inflammatory Bowel Disease - A single-center retrospective studyECCO'25Year: 2025
Authors: Saidani, R.(1)*;Cherif, D.(1);Hassine, H.(1);Yacoub, H.(1);Debbabi, H.(1);Kchir, H.(1);Maamouri, N.(1);
(1)University hospital of La Rabta, Gastroenterology B, Tunis, Tunisia;
P0457: Food avoidance, eating disorders and disability in Inflammatory Bowel Disease: a cross-sectional analysis of risk factorsECCO'25Year: 2025
Authors: Nardone, O.M.(1)*;D'Amico, F.(2);Calabrese, G.(3);Parigi, T.L.(2);La Mantia, A.(3);Bencardino, S.(2);Gargiulo, M.A.(4);Rutoli, L.(4);Palumbo, F.(3);Bonacci, L.(3);Rispo, A.(3);Testa, A.(3);Danese, S.(2);Castiglione, F.(3);
(1)University of Naples Federico II, Department of Public Health, Naples, Italy;(2)IRCCS San Raffaele Hospital and Vita-Salute San Raffaele University, Gastroenterology and Endoscopy, Milan, Italy;(3)University of Naples Federico II, Department of Clinical Medicine and Surgery, Naples, Italy;(4)University of Naples Federico II, School of Medicine and Surgery, Naples, Italy;
1. Nardone OM et al, Italian validation of the ibd-disk tool for the assessment of disability in inflammatory bowel diseases: a cross-sectional multicenter study, Digestive and Liver Disease, Nov 2024 on press
P0458: The burden, risk factors and laboratory evaluation of anemia in patients with Inflammatory Bowel DiseaseECCO'25Year: 2025
Authors: Foteinogiannopoulou, K.(1)*;Orfanoudaki, E.(1);Theodoraki, E.(1);Gkiaouraki, E.(1);Niniraki , M.(2);Prinari, I.(2);Kalyvianaki, K.(3);Kampa, M.(4);Koutroubakis, I.(1);
(1)University Hospital of Heraklion, Department of Gastroenterology, Heraklion, Greece;(2)University Hospital of Heraklion, Experimental Endocrinology-Clinical Immunology Lab, Heraklion, Greece;(3)University of Crete- School of Medicine, Laboratory of Experimental Endocrinology, Heraklion, Greece;(4)University of Crete- School of Medicine- University Hospital of Heraklion, Experimental Endocrinology-Clinical Immunology Lab, Heraklion, Greece;
1. Kulnigg S, Gasche C. Systematic review: managing anemia in Crohn’s disease. Aliment Pharmacol Ther. 2006;24:1507–232
2. Gordon H, Burisch J, Ellul P, Karmiris K, Katsanos K, Allocca M, Bamias G, Barreiro-de Acosta M, Braithwaite T, Greuter T, Harwood C, Juillerat P, Lobaton T, Müller-Ladner U, Noor N, Pellino G, Savarino E, Schramm C, Soriano A, Michael Stein J, Uzzan M, van Rheenen PF, Vavricka SR, Vecchi M, Zuily S, Kucharzik T. ECCO Guidelines on Extraintestinal Manifestations in Inflammatory Bowel Disease. J Crohns Colitis. 2024 Jan 27;18(1):1-37.
P0459: Plasma IgA as a biomarker and IL-21 as a potential therapeutic target in Inflammatory Bowel DiseaseECCO'25Year: 2025
Authors: Tsai, T.(1,2,3)*; Hsu, J.L.(4,5);
(1)China Medical University Hospital, Center for Digestive Medicine, Taichung City, Taiwan;(2)National Health Research Institutes, Immunology Research Center, Zhunan, Taiwan;(3)China Medical University, School of Medicine, Taichung, Taiwan;(4)China Medical University, Graduate Institute of Biomedical Sciences, Taichung, Taiwan;(5)China Medical University, Drug Development Center, Taichung, Taiwan;
1. Lee B, Hsu J, Tsai T. Correlation between plasma IgA level and biological therapy in inflammatory bowel disease. J Can Assoc Gastroenterol. 2024;194(7):241. doi:10.1093/jcag/gwad061.241
2. Rodriguez-Lago I, Marigorta UM, Barreiro-de Acosta M. Preclinical inflammatory bowel disease: back to the future. Gastroenterology. 2021;160(1):475-476. doi:10.1053/j.gastro.2020.04.081
P0460: Intestinal ultrasound in inflammatory bowel disease: Do we really need experts to monitor our patients?ECCO'25Year: 2025
Authors: Achemlal, A.(1)*;Taibi, O.(2);Ouahid, S.(1);Salaheddine, T.(2);Saouab, R.(2);Tamzaourte, M.(1);
(1)Mohamed V Military Training Hospital, Gastro Enterology 1, Rabat, Morocco;(2)Mohamed V Military Training Hospital, Radiology, Rabat, Morocco;
P0461: Does Number of Truelove and Witts’ Systemic Criteria at Time of Presentation with Acute Severe Ulcerative Colitis have an Effect on Severity of Systemic Features and Patient Outcomes?ECCO'25Year: 2025
Authors: Wu, M.Y.(1,2)*;Nario, S.(1);Tung, C.(1);Kiely, C.(1);
(1)Royal North Shore Hospital, Department of Gastroenterology, St Leonards, Australia;(2)University of Sydney, Northern Clinical School, Sydney, Australia;
1. Dinesen LC, Walsh AJ, Protic MN, et al. The pattern and outcome of acute severe colitis. J Crohns Colitis. 2010;4(4):431-437. doi:10.1016/J.CROHNS.2010.02.001
2. Sturm A, Maaser C, Calabrese E, et al. ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 2: IBD scores and general principles and technical aspects. J Crohns Colitis. 2019;13(3):273-284. doi:10.1093/ECCO-JCC/JJY114
P0463: Co-infection of Clostridium innocuum Worsens Outcomes in Inflammatory Bowel Disease Patients with Clostridioides difficile InfectionECCO'25Year: 2025
Authors: Ching Reigh, H.(1)*;Le, P.H.(2);Chiu, C.H.(3);Chiu, C.T.(2);Su , M.Y.(4);Kuo, C.J.(2);Chang, M.L.(2);
(1)Chang Gung Memorial Hospital, Department of Internal Medicine, Taoyuan, Taiwan;(2)Chang Gung Memorial Hospital, Department of Gastroenterology and Hepatology, Linkou- Taoyuan, Taiwan;(3)Chang Gung Memorial Hospital, Department of Pediatric Infectious Diseases, Linkou- Taoyuan, Taiwan;(4)Chang Gung Memorial Hospital, Department of Gastroenterology and Hepatology, Tucheng- New Taipei City, Taiwan;
1.Yu S, Ge X, Xu H, Tan B, Tian B, Shi Y, Dai Y, Li Y, Hu S, Qian J. Gut microbiome and mycobiome in inflammatory bowel disease patients with Clostridioides difficile infection. Front Cell Infect Microbiol. 2023;13:1129043. doi:10.3389/fcimb.2023.1129043.
2.Wu HY, Kuo CJ, Chou CH, Ho MW, Chen CL, Hsu TS, Chen YC, Chiang-Ni C, Chen YM, Chiu CH, Lai CH. Clostridium innocuum, an emerging pathogen that induces lipid raft-mediated cytotoxicity. Virulence. 2023;14(1):2265048. doi: 10.1080/21505594.2023.2265048.
3Bai M, Guo H, Zheng XY. Inflammatory bowel disease and Clostridium difficile infection: clinical presentation, diagnosis, and management. Therap Adv Gastroenterol. 2023;16:17562848231207280. doi:10.1177/17562848231207280.
4.Le PH, Chiu CT, Yeh PJ, Pan YB, Chiu CH. Clostridium innocuum infection in hospitalised patients with inflammatory bowel disease. J Infect. 2022;84(3):337-342. doi: 10.1016/j.jinf.2021.12.031.
P0464: exploring the Relationship Between Gender, Age at Onset, and the Presence and Severity of Ano-Perineal Lesions in Inflammatory Bowel DiseaseECCO'25Year: 2025
Authors: Elommal, H.(1)*;Koulali, H.(2);Elmqaddem, O.(2);Zazour, A.(1);ismaili, Z.(2);Kharrasse, G.(2);
(1)Service d’Hépato-gastro-entérologie CHU MOHAMMED VI Oujda- Université Mohammed Premier Oujda- Laboratoire de recherche de maladie de l’appareil digestif LARMAD.MAROC, Service d’Hépato-gastro-entérologie CHU MOHAMMED VI Oujda, Oujda, Morocco;(2)Service d’Hépato-gastro-entérologie CHU MOHAMMED VI Oujda- Université Mohammed Premier Oujda- Laboratoire de recherche de maladie de l’appareil digestif LARMAD.MAROC, Service d’Hépato-gastro-entérologie CHU MOHAMMED VI Oujda- Université Mohammed Premier Oujda, Oujda, Morocco;
P0465: Chromoendoscopy for Dysplasia Detection in High-Risk IBD Patients: A Decade of Experience at a Tertiary Care CentreECCO'25Year: 2025
Authors: Weisshof, R.(1)*;Postnikov, M.(2);Gorelik, Y.(1);Ben-Hur, D.(3);Waterman, M.(1);Koifman, E.(1);
(1)Rambam Health Care Campus, Department of Gastroenterology, Haifa, Israel;(2)Rambam Health Care Campus, Internal Medicine Departments B, Haifa, Israel;(3)Rambam Health Care Campus, Internal Medicine Departments H, Haifa, Israel;
P0466: Impact of the COVID-19 Pandemic on Clinical Presentation and Management of Inflammatory Bowel Disease: A Multicentre Study in the West Midlands, UKECCO'25Year: 2025
Authors: Rafique, H.(1)*;Ismail, A.(1);Umar, N.(1);Hasaan, S.(2);Rahania, K.(2);Saeed, M.H.(1);Harvey, P.(2);De Silva, S.(1);
(1)The Dudley Group NHS Foundation Trust, Gastroenterology, Dudley, United Kingdom;(2)The Royal Wolverhampton NHS Trust, Gastroenterology, Wolverhampton, United Kingdom;
P0467: Increased risk for depression and low quality of life in patients with active inflammatory bowel diseaseECCO'25Year: 2025
Authors: TopalaM.D.- PhD student, M.(1,2)*;Ionescu, V.(3);Iacob, R.(1,4);Gheorghe, C.(1,4);
(1)Fundeni Clinical Institute, Center of Gastroenterology and Hepatology, Bucharest, Romania;(2)Carol Davila University of Medicine and Pharmacy, Doctoral School, Bucharest, Romania;(3)Bucharest Clinical Emergency Hospital, Infection Control Unit, Bucharest, Romania;(4)Carol Davila University of Medicine and Pharmacy, Faculty of Medicine, Bucharest, Romania;
P0468: Prevalence of traditional cardiovascular risk factors in Crohn's diseaseECCO'25Year: 2025
Authors: Fissah, M.(1)*;Rechach, A.(1);Charifi, M.(1);Menzou, F.(1);Djouhri, M.(1);Touati, N.(1);Talbi, L.(1);Chibane, A.(1);
(1)University Hospital center of Douera, Medicine, Algiers, Algeria;
P0469: Impact of gynecologic malignancy on ileal pouch-anal anastomosis survival: a matched case-control studyECCO'25Year: 2025
Authors: Unal, E.(1)*;Lavryk, O.(1);Kanters, A.(1);Spivak, A.(1);Falloon, K.(2);Naseer, M.(2);Qazi, T.(2);Lipman, J.(1);Michener, C.(3);Hull, T.(1);Debernardo, R.(3);Holubar, S.(1);
(1)Cleveland Clinic Foundation, Department of Colorectal Surgery, Cleveland, United States;(2)Cleveland Clinic Foundation, Department of Gastroenterology, Cleveland, United States;(3)Cleveland Clinic Foundation, Department of Gynecology, Cleveland, United States;
P0470: Albumin as a prognostic marker in IBD : Insights from a Tertiary Care Hepato-Gastroenterology Center ExperienceECCO'25Year: 2025
Authors: Adamou Mainassra, F.(1)*;Koulali, H.(2);Hassini, A.(2);Essadi, B.(2);Douhri, I.(3);Elmqddem, O.(2);Zazour, A.(2);Zahi, I.(2);Kharrasse, G.(2);
(1)Hepato-Gastroenterology Service- Mohammed VI University Hospital Center CHU- Oujda- Mohammed First University- Oujda- Research Laboratory for Digestive System Diseases LARMAD- Morocco, Departement, Department of Hepato-Gastroenterology, Morocco;(2)Hepato-Gastroenterology Service- Mohammed VI University Hospital Center Oujda, Department of Hepato-Gastroenterology, oujda, Morocco;(3)douhriikram@gmail.com, Department of Hepato-Gastroenterology, oujda, Morocco;
P0471: Prevalence and risk factors for gallstone and renal stone formation in patients with intestinal Behçet’s diseaseECCO'25Year: 2025
Authors: Park, J.(1)*;Jae Hee, C.(1);
(1)Yonsei University college of medicine, Internal medicine, Seoul, Korea- Republic Of;
1. Sakane T, Takeno M, Suzuki N, Inaba G. Behçet’s disease. NEngl J Med 1999;341:1284-1291.
2. Kaklamani VG, Kaklamanis PG. Treatment of Behçet’s disease--an update. Semin Arthritis Rheum 2001;30:299-312.
3. Kim DH, Cheon JH. Intestinal Behçet’s disease: a true inflammatorybowel disease or merely an intestinal complication ofsystemic vasculitis? Yonsei Med J 2016;57:22-32.
4. Suzuki Y, Hagiwara T, Kobayashi M, Morita K, Shimamoto T,Hibi T. Long-term safety and effectiveness of adalimumab in462 patients with intestinal Behçet’s disease: results from alarge real-world observational study. Intest Res 2021;19:301-312.
5. Song EM, Yang SK. Natural history of inflammatory boweldisease: a comparison between the East and the West. IntestRes 2022;20:418-430.
P0472: Artificial intelligence-enabled histology is comparable in performance to pathologists in assessing histological remission in inflammatory bowel disease: a systematic review, meta-analysis and meta-regressionECCO'25Year: 2025
Authors: Puga Tejada, M.A.(1)*;Majumder, S.(1);Maeda, Y.(1);Zammarchi, I.(1);Ditonno, I.(1);Santacroce, G.(1);Capobianco, I.(1);Robles-Medranda, C.(2);Ghosh, S.(1);Iacucci, M.(1);
(1)APC Microbiome Ireland- University College Cork UCC, College of Medicine and Health, Cork, Ireland;(2)Instituto Ecuatoriano de Enfermedades Digestivas, Gastroenterology and Endoscopy Division, Guayaquil, Ecuador;
1. Turner D, Ricciuto A, Lewis A, et al. STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD. Gastroenterology. 2021;160(5):1570-1583. doi:10.1053/j.gastro.2020.12.031
2. Gupta A, Yu A, Peyrin-Biroulet L, Ananthakrishnan AN. Treat to Target: The Role of Histologic Healing in Inflammatory Bowel Diseases: A Systematic Review and Meta-analysis. Clinical Gastroenterology and Hepatology. 2021;19(9):1800-1813.e4. doi:10.1016/j.cgh.2020.09.046
3. Iacucci M, Santacroce G, Zammarchi I, et al. Artificial intelligence and endo-histo-omics: new dimensions of precision endoscopy and histology in inflammatory bowel disease. Lancet Gastroenterol Hepatol. Published online May 2024. doi:10.1016/S2468-1253(24)00053-0Iacucci M, Santacroce G, Zammarchi I, et al. Artificial intelligence and endo-histo-omics: new dimensions of precision endoscopy and histology in inflammatory bowel disease. Lancet Gastroenterol Hepatol. Published online May 2024. doi:10.1016/S2468-1253(24)00053-0
P0473: Establishment of a prediction model for endoscopic activity of Ulcerative Colitis based on Intestinal ultrasound combined with biochemical indicatorsECCO'25Year: 2025
Authors: Zhao, Y.(1)*;Pei, J.(1);Li, Y.(2);Pu, T.(1);Wen, H.(1);
(1)The First Affiliated Hospital of Zhengzhou University, Department of Gastroenterology, Zhengzhou, China;(2)The First Affiliated Hospital of Zhengzhou University, Department of Ultrasound, Zhengzhou, China;
P0474: Five-Year Clinical Outcomes and Disease Course of Newly-Diagnosed Moderate-to-Severe Ulcerative Colitis: A Prospective Nationwide Multicentre MOSAIK Cohort Study in KoreaECCO'25Year: 2025
Authors: Ye, B.D.(1)*;Kim, H.J.(2);Park, D.I.(3);Park, Y.S.(4);Lee, K.M.(5);Im, J.P.(6);Jung, S.A.(7);Jeen, Y.T.(8);Cha, J.M.(9);Cheon, J.H.(10);Hong, S.N.(11);Kim, Y.(12);Choi, J.M.(12);Lee, Y.(12);Lee, C.K.(2);
(1)University of Ulsan College of Medicine- Asan Medical Center, Department of Gastroenterology and Inflammatory Bowel Disease Center, Seoul, Korea- Republic Of;(2)Kyung Hee University Hospital- Kyung Hee University College of Medicine, Gastroenterology- Center for Crohn’s and Colitis, Seoul, Korea- Republic Of;(3)Kangbuk Samsung Hospital- Sungkyunkwan University School of Medicine, Internal Medicine, Seoul, Korea- Republic Of;(4)Nowon Eulji Hospital- Eulji University School of Medicine, Internal Medicine, Seoul, Korea- Republic Of;(5)St. Vincent’s Hospital- College of Medicine- The Catholic University of Korea College of Medicine, Internal Medicine, Suwon, Korea- Republic Of;(6)Seoul National University College of Medicine, Internal Medicine and Liver Research Institute, Seoul, Korea- Republic Of;(7)Ewha Womans University College of Medicine, Internal Medicine, Seoul, Korea- Republic Of;(8)Korea University- Anam Hospital- Korea University College of Medicine, Internal Medicine, Seoul, Korea- Republic Of;(9)Kyung Hee University Hospital at Gangdong- Kyung Hee University College of Medicine, Internal Medicine, Seoul, Korea- Republic Of;(10)Severance Hospital- Yonsei University College of Medicine, Internal Medicine, Seoul, Korea- Republic Of;(11)Samsung Medical Center- Sungkyunkwan University School of Medicine, Internal Medicine, Seoul, Korea- Republic Of;(12)Janssen Korea Ltd., Medical Affairs, Seoul, Korea- Republic Of;
1. Lee CK, Lee KM, Park DI, et al. A new opportunity for innovative inflammatory bowel disease research: the moderate-to-severe ulcerative colitis in Korea (MOSAIK) cohort study. Intest Res. 2019;17(1):1–5.
P0475: Differential characteristics and predictors of time to colectomy in ulcerative colitis: stratified by medical refractory disease vs. colitis-associated neoplasiaECCO'25Year: 2025
Authors: Kim, J.(1)*;Hebert-milette, I.(1);Conner, J.(1);Borowski, K.(1);Stempak, J.(1);Lee, S.H.(1);Silverberg, M.S.(1);
(1)Mount Sinai Hospital, Zane Cohen Centre for Digestive Diseases, Toronto, Canada;
