Hospital Universitario Virgen del Rocío, UGC Digestive Diseases, Seville, Spain

¹BÜHLMANN Laboratories AG, Development, Schönenbuch, Switzerland, ²University Clinic Münster, Pediatric Rheumatology and Immunology, Münster, Germany

Internal Medicine, The Catholic University of Korea, Seoul, Korea Republic of

¹A.O.O.R. ‘Villa Sofia-Cervello’, IBD Unit - Department of Medicine, Palermo, Italy, ²A.O.U. Policlinico ‘G. Martino’, Inflammatory bowel disease Unit, Messina, Italy, ³A.O.U. Policlinico ‘G. Giaccone’, Gastroenterology and Hepatology Unit, Palermo, Italy, ⁴A.O. ‘Cannizzaro’, Inflammatory Bowel Disease Unit, Catania, Italy, ⁵A.O.O.R. ‘S. Elia- M. Raimondi’, Gastroenterology Unit, Caltanissetta, Italy, ⁶A.R.N.A.S. ‘Civico Di Cristina Benfratelli’, Gastroenterology and endoscopy Unit, Palermo, Italy, ⁷A.O. ‘Guzzardi’, Gastroenterology Unit, Vittoria, Italy, ⁸A.O.O.R. ‘Papardo Piemonte’, Gastroenterology Unit, Messina, Italy

¹Department of Gastroenterology and Hepatology, UMC Utrecht, Utrecht, The Netherlands, ²Department of Gastroenterology and Hepatology, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands, ³Department of Gastroenterology and Hepatology, Elisabeth-TweeSteden Ziekenhuis, Tilburg, The Netherlands, ⁴Department of Gastroenterology and Hepatology, Catharina Ziekenhuis, Eindhoven, The Netherlands, ⁵Department of Gastroenterology and Hepatology, St. Antonius Ziekenhuis, Nieuwegein, The Netherlands, ⁶Department of Gastroenterology and Hepatology, Leiden UMC, Leiden, The Netherlands, ⁷Department of Gastroenterology and Hepatology, UMC Groningen, Groningen, The Netherlands, ⁸Department of Gastroenterology and Hepatology, Zuyderland Ziekenhuis, Sittard, The Netherlands

¹Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden, ²Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, ³Clinical Epidemiology Division, Department of Medicine Solna, Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden, ⁴Department of Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden

¹Department of Gastroenterology and Hepatology, LUMC, Leiden, The Netherlands, ²Department of Medical Microbiology, LUMC, Leiden, The Netherlands, ³Department of Gastroenterology, Haaglanden Medical Center, The Hague, The Netherlands

¹Department of Anaesthesiology/Hyperbaric Medicine, Academic Medical Centre, Amsterdam, The Netherlands, ²Department of Gastroenterology and Hepatology, Academic Medical Centre,Amsterdam, The Netherlands, ³Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands, ⁴Department of Radiology and Nuclear Medicine, Academic Medical Centre, Amsterdam, The Netherlands

¹Radboud University Medical Centre, Gastroenterology, Nijmegen, The Netherlands, ²Franciscus Gasthuis and Vlietland, Gastroenterology, Rotterdam, The Netherlands, ³Medisch Spectrum Twente, Gastroenterology, Enschede, The Netherlands, ⁴Onze Lieve Vrouw Gasthuis, Gastroenterology, Amsterdam, The Netherlands, ⁵Pharmacovigilance Centre LAREB, Pharmacovigilancy, ‘s-Hertogenbosch, The Netherlands, ⁶Jeroen Bosch Ziekenhuis, Gastroenterology, ‘s-Hertogenbosch, The Netherlands

¹MZV für Immunologie, Gastroenterology, Hamburg, Germany, ²Health Economics and Outcomes Research Ltd, Health Economics, Cardiff, UK, ³Shield Therapeutics PLC, Medical, London, UK, ⁴Norgine Ltd, Medical, Rueil Malmaison, France

¹Department of Gastroenterology, Soroka Medical Center, Beer Sheva, Israel, ²Department of Public Health, Ben-Gurion University of the Negev, Beer Sheva, Israel, ³Department of Social Work, Ben-Gurion University of the Negev, Beer Sheva, Israel, ⁴Department of Bacteriology and Immunology, Ben-Gurion University of the Negev, Beer Sheva, Israel, ⁵Department of Health Systems Management, Ben-Gurion University of the Negev, Beer Sheva, Israel, ⁶Department of Health Sciences, Ben-Gurion University of the Negev, Metar, Israel

Guy’s and St Thomas’ NHS Foundation Trust, St Thomas Hospital, London, UK

¹Translational Gastroenterology Unit, Nuffield Department of Experimental Medicine- University of Oxford, Oxford, UK, ²Division of Gastroenterology, Rabin Medical Center- Petah Tikva- Israel and Sackler Faculty of Medicine- Tel Aviv University, Tel Aviv, Israel, ³Humanitas University- IBD Center, Division of Gastroenterology- Rozzano, Milan, Italy, ⁴Virginia Mason Medical Center, Seattle, WA, USA, ⁵IBD Clinic- Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, Mexico, ⁶Pfizer Inc., Lima, Peru, Peru, ⁷Pfizer Inc., Collegeville, PA, USA, ⁸Syneos Health, Morrisville, NC, USA, ⁹Pfizer Inc., New York, NY, USA, ¹⁰Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA

¹Inflammatory Bowel Disease Unit, Department of Clinical and Experimental Medicine, University of Messina, A.O.U. Policlinico ‘G. Martino’, Messina, Italy, ²Department of Economics, University of Messina, Messina, Italy

Royal Wolverhampton NHS Trust, Colorectal Surgery, Wolverhampton, UK

¹Asan Medical Center, University of Ulsan College of Medicine, Department of Gastroenterology, Seoul, Korea Republic of, ²Asan Medical Center, University of Ulsan College of Medicine, Inflammatory Bowel Disease Center, Seoul, Korea Republic of, ³Asan Medical Center, University of Ulsan College of Medicine, Department of Clinical Epidemiology and Biostatistics, Seoul, Korea Republic of, ⁴Asan Medical Center, University of Ulsan College of Medicine, Department of Gastroenterology and Inflammatory Bowel Disease Center, Seoul, Korea Republic of

¹Nova Scotia Health Authority, Digestive Care and Endoscopy, Halifax, Canada, ²Dalhousie University, Medicine, Halifax, Canada

¹School of Pharmaceutical Sciences, Sun Yat-Sen Unversity, Guangzhou, China, ²Department of Gastroenterology, the Sixth Affiliated Hospital- Sun Yat-sen University, Guangzhou, China

¹Leiden University Medical Center, Department of Gastroenterology and Hepatology, Leiden, The Netherlands, ²Radboud University Medical Centre, Department of Gastroenterology and Hepatology, Nijmegen, The Netherlands, ³Maastricht University Medical Centre, Department of Gastroenterology and Hepatology, Maastricht, The Netherlands, ⁴University Medical Centre Groningen, Department of Gastroenterology and Hepatology, Groningen, The Netherlands, ⁵Amsterdam University Medical Centre- Academic Medical Centre, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁶Haaglanden Medical Centre, Department of Gastroenterology and Hepatology, Den Haag, The Netherlands, ⁷Amsterdam University Medical Centre- Vrije Universiteit Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁸Amphia Hospital, Department of Gastroenterology and Hepatology, Breda, The Netherlands, ⁹Onze Lieve Vrouwe Gasthuis, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands, ¹⁰Franciscus Gasthuis and Vlietland, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands

¹Department of Data Analytics and Design Strategy, RTI Health Solutions, Manchester, UK, ²Outcomes Research and Epidemiology, Shire - a Takeda Company, Health Economics, Lexington, USA, ³School of Pharmacy, University of Washington, Seattle, USA, ⁴Dr Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai Medical Center, New York, USA, ⁵Division of Gastroenterology, University of Calgary, Calgary, Canada, ⁶Department of Gastroenterology, University Hospital of Nancy-Brabois, Vandœuvre-lès-Nancy, France, ⁷IBD Center, Humanitas University, Milan, Italy, ⁸Department of Gastroenterology, University Hospital Leuven, Leuven, Belgium, ⁹Zymo Consulting Group, Clinical Development, Newtown Square, USA, Clinical Development, ¹⁰Shire - a Takeda compa#ny, Zug, Switzerland