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P076: The endocannabinoid system in the intestinal biopsies of children with Inflammatory Bowel DiseaseECCO'21 Virtual
Year: 2021
Authors: Creoli, M.(1);Strisciuglio, C.(2); Vitale, A.(2); Oglio, F.(3);Paino, S.(1);Luongo, L.(1);Tortora, C.(2);Argenziano, M.(2); Di Paola, A.(1);Maione, S.(1);Rossi, F.(2);
(1)Università degli Studi della Campania 'L.Vanvitelli', Department of Experimental Medicine, Naples, Italy;(2)Università degli Studi della Campania 'L.Vanvitelli', Department of Woman- Child and General and Specialized Surgery, Naples, Italy;(3)Università degli Studi di Napoli 'Federico II, Department of Translational Medical Science, Naples, Italy
P077: What matters to Ulcerative Colitis patients when they make treatment decisions? A systematic reviewECCO'21 Virtual
Year: 2021
Authors: Folan, A.M.(1);Jones, G.(1);Baker, D.(2);Brown, S.(3);Lee, M.(4);Lobo, A.(5);
(1)Leeds Beckett University, Department of Psychology, Leeds, United Kingdom;(2)Sheffield Teaching Hospitals, Academic Foundation Doctor, Sheffield, United Kingdom;(3)Sheffield Teaching Hospitals, Department of General Surgery, Sheffield, United Kingdom;(4)Sheffield Teaching Hospitals, Department of Oncology and Metabolism, Sheffield, United Kingdom;(5)Royal Hallamshire Hospital, Department of Gastroenterology, Sheffield, United Kingdom
P078: Proteomics and Lipidomics Analysis Revealed Alterations of Complement Activation and Lipid Metabolism in peripheral blood mononuclear cells of Inflammatory Bowel Disease PatientsECCO'21 Virtual
Year: 2021
Authors: Notararigo, S.(1);Bravo, S.(1);Martin-Pastor, M.(2);Baston-Rey, I.(3);Quiroga-Castiñeira, A.(3);Dominguez-Munoz, J.E.(3);Domínguez Medina, E.(1);Barreiro-de Acosta, M.(3);
(1)University Hospital Santiago De Compostela CHUS, Instituto de Investigación Sanitaria de Santiago IDIS, Santiago De Compostela, Spain;(2)CACTUS, Unidade de Resonancia Magnética, Santiago, Spain;(3)University Hospital Santiago De Compostela CHUS, Department of Gastroenterology- IBD Unit, Santiago De Compostela, Spain
P079: Valproic acid increases MiR449a expression in intestinal mucosa from patients with inflammatory bowel diseaseECCO'21 Virtual
Year: 2021
Authors: Felice, C.(1);Lewis, A.(2);Armuzzi, A.(3);Lindsay, J.O.(4);Silver, A.(2);
(1)University of Padua, Internal Medicine DIMED- Medicine 1- Ca' Foncello Hospital, Treviso, Italy;(2)Queen Mary University of London, Centre for Genomics and Child Health- Blizard Institute- Barts and The London School of Medicine and Dentistry, London, United Kingdom;(3)Catholic University, IBD Unit- Gemelli Hospital Foundation IRCCS, Rome, Italy;(4)Queen Mary University of London, Centre for Immunobiology- Blizard Institute- Barts and The London School of Medicine and Dentistry, London, United Kingdom
P080: Burden of Disease and Cost of Illness of Inflammatory Bowel Diseases in PortugalECCO'21 Virtual
Year: 2021
Authors: Magro, F.(1);Portela, F.(2);Lago, P.(3);Chagas, C.(4);Moreira, F.(5);Pereira, F.(5);Rodrigues, B.(6);Pedrosa, H.(5);Correia, L.(7);
(1)Centro Hospitalar São João, Gastroenterology, Porto, Portugal;(2)Centro Hospitalar Universitário de Coimbra, Gastroenterolgy, Coimbra, Portugal;(3)Centro Hospitalar e Universitário do Porto, Gastroenterology, Porto, Portugal;(4)Centro Hospitalar Lisboa Ocidental, Gastroenterology, Lisboa, Portugal;(5)IQVIA, Consulting, Lisboa, Portugal;(6)Janssen, Market Access, Lisboa, Portugal;(7)Centro Hospitalar Lisboa Norte, Gastroenterology, Lisboa, Portugal
P081: Resolvin D2 attenuates colonic inflammation of Crohn’s disease patientsECCO'21 Virtual
Year: 2021
Authors: Pascoal, L.B.(1);Palma, B.B.(1);Chaim, F.H.(1);Nogueira, G.(2);Rodrigues, B.L.(1);Ayrizono, M.L.S.(1);Velloso, L.A.(2);Leal, R.F.(1);
(1)University of Campinas UNICAMP, Inflammatory Bowel Disease Research Laboratory- Gastrocenter- Colorectal Surgery Unit- School of Medical Sciences, Campinas, Brazil;(2)University of Campinas UNICAMP, Laboratory of Cell Signaling- School of Medical Sciences, Campinas, Brazil
P082: Assessment of anti-inflammatory effect of high acetate administration in UC patient-derived epithelial monolayer culturesECCO'21 Virtual
Year: 2021
Authors: Deleu, S.(1);Arnauts, K.(1,2);Machiels, K.(1);Huys, G.R.B.(3,4);Thevelein, J.(4,5,6);Raes, J.(3,4);Vermeire, S.(1,7);
(1)KU Leuven, Department of Chronic Diseases- Metabolism & Ageing CHROMETA, Leuven, Belgium;(2)KU Leuven, Department of Development and Regeneration- Stem Cell Institute Leuven, Leuven, Belgium;(3)KU Leuven, Department of Microbiology and Immunology- Rega Institute, Leuven, Belgium;(4)VIB, Center for Microbiology, Leuven, Belgium;(5)Erasmus High School, NovelYeast bv- Open Bio-Incubator, Brussels, Belgium;(6)KU Leuven, Laboratory of Molecular Cell Biology- Institute of Botany and Microbiology, Leuven, Belgium;(7)University Hospitals Leuven- KU Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium
P083: High prevalence of ulcerative appendicitis in UC patients without colonic disease activityECCO'21 Virtual
Year: 2021
Authors: Heuthorst, L.(1);Mookhoek, A.(2);Wildenberg, M.(3);D'Haens, G.(4);Bemelman, W.(1);Buskens, C.(1);
(1)Amsterdam UMC- location AMC, Department of Surgery, Amsterdam, The Netherlands;(2)Amsterdam UMC, Department of Pathology, Amsterdam, The Netherlands;(3)Amsterdam UMC, Tytgat Institute for Liver and Intestinal Research, Amsterdam, The Netherlands;(4)Amsterdam UMC, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands
P084: C-Reactive Protein Correlates with Tumor Necrosis Factor-α in Ulcerative ColitisECCO'21 Virtual
Year: 2021
Authors: McDonagh, P.(1);O'Connell, F.(2);O'Connell, J.(1);Argue, R.(1);Corcoran, R.(1);Kevans, D.(1);O'Sullivan, J.(2);
(1)St James's Hospital, Department of Gastroenterology, Dublin, Ireland;(2)Trinity College Dublin, Trinity Translational Medicine Institute, Dublin, Ireland
P085: Expression profiling of Wnt pathway genes in colon biopsies of patients with Ulcerative ColitisECCO'21 Virtual
Year: 2021
Authors: Lu, C.(1);Shah, D.(1);Wijnands, A.(2);Oldenburg, B.(2);Yeh, W.C.(3);Vanhove, G.(4);Li, Y.(1);
(1)Surrozen Inc., Discovery Biology, South San Francisco, United States;(2)University Medical Center Utrecht, Division Internal Medicine and Dermatology - Department Gastroenterology and hepatology, Utrecht, The Netherlands;(3)Surrozen Inc., In vivo pharmacology, South San Francisco, United States;(4)Surrozen Inc., Clinical Development, South San Francisco, United States
P086: Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon immune dysregulation and intestinal permeability in a stress-induced colonic inflammationECCO'21 Virtual
Year: 2021
Authors: Martin-Hernández, D.(1);Robledo Montaña, J.(2);López-Gutiérrez, I.(2);González-Prieto, M.(2);González Bris, Á.(2);Ulecia-Morón, C.(2);MacDowell, K.(2);Tendilla-Beltrán, H.(2);Moreno, B.(2);Calleja-Rodríguez, N.(2);Rodríguez-Mascarenhas, S.(2);Caso, J.R.(2);García-Bueno, B.(2);Marín-Jiménez, I.(3);Leza, J.C.(2);Menchen Viso, L.A.(3);
(1)General University Hospital Gregorio Marañón, Department of Psychatry, Madrid, Spain;(2)Universidad Complutense- Madrid, Pharmacology, Madrid, Spain;(3)General University Hospital Gregorio Marañón, Department of Gastroenterology and Digestive System Medicine, Madrid, Spain
P087: The role of bile acids in mediating fibrosis in inflammatory bowel diseaseECCO'21 Virtual
Year: 2021
Authors: Hazel, K.(1);McGinley, N.(1);O'Toole, A.(2);Keely, S.(1);
(1)Royal College of Surgeons in Ireland, Department of Molecular Medicine, Dublin, Ireland;(2)Beaumont Hospital, Department of Gastroenterology, Dublin, Ireland
P088: Neurotuberculosis in a patient with Ulcerative Colitis using adalimumab for a long period in BrazilECCO'21 Virtual
Year: 2021
Authors: Facanali, M.(1);Bortolozzo Graciolli Facanali, C.(1);Rodrigues Boarini, L.(1);Vaz Safatle Ribeiro, A.(1);Sobrado, C.W.(1);
(1)University of São Paulo School of Medicine, Department of Gastroenterology and Division of Colorectal Surgery, Sao Paulo, Brazil
P089: IFNγ-macrophages could mediate EMT in Crohn’s diseaseECCO'21 Virtual
Year: 2021
Authors: Marín-Aracil, J.(1);Barrachina , M.D.(1);Bauset, C.(1);Cosin-Roger, J.(2);Coll, S.(1);Calatayud, S.(1);Antonio, L.S.(3);Ortiz-Masiá, D.(1);
(1)Universitat de Valencia, Facultad de Medicina, Valencia, Spain;(2)Hospital Doctor Peset, Fisabio, Valencia, Spain;(3)Hospital Doctor Peset, Servicio Digestivo, Valencia, Spain
P090: Risk of Rectal Cancer after Colectomy in Patients with Inflammatory Bowel Disease – A Nationwide Population-based Danish Cohort Study 1978-2018ECCO'21 Virtual
Year: 2021
Authors: Akimenko, E.(1);Bjerrum, J.T.(1);Allin, K.H.(2);Iversen, A.T.(2);Jess, T.(2);
(1)Copenhagen University Hospital- Herlev and Gentofte Hospital, Department of Gastroenterology and Hepatology, Copenhagen, Denmark;(2)Aalborg University- Faculty of Medicine, Department of Clinical Medicine- Center for Molecular Prediction of Inflammatory Bowel Disease- PREDICT, Copenhagen, Denmark
P091: Switching to TNFi versus non-TNFi biologics in Crohn’s Disease patients: Real-world outcomes from a German claims data analysisECCO'21 Virtual
Year: 2021
Authors: Antolin-Fontes, B.(1);Borsi, A.(2);Nissinen, R.(3);Bravatà, I.(4);Barthelmes, J.N.(5);Le Bars, M.(6);Lee, J.(2);Maywald, U.(7);Bokemeyer, B.(8);Wilke, T.(9);Ghiani, M.(9);
(1)Ingress-Health, Real World Analytics, Berlin, Germany;(2)Janssen-Cilag, Ltd., High Wycombe, United Kingdom;(3)Janssen-Cilag, Oy, Espoo, Finland;(4)Janssen-Cilag, S.p.A., Milan, Italy;(5)Janssen-Cilag, GmbH, Neuss, Germany;(6)Janssen-Cilag, Sarl, Issy-les-Moulineaux, France;(7)AOK Plus, Drug Department, Dresden, Germany;(8)Gastroenterology Practice, Gastroenterology, Minden, Germany;(9)IPAM - Institut für Pharmakoökonomie und Arzneimittellogistik, e.V., Wismar, Germany
P092: Development and evaluation of i-Tracker Ustekinumab and i-Tracker Anti-ustekinumab kits: fast and innovative chemiluminescent assays for the monitoring of patients treated with ustekinumabECCO'21 Virtual
Year: 2021
Authors: Noguier, G.(1);Montaillier, C.(1);Daviere, S.(2);Yang, Y.(2);Colombeau, L.(1);Parussini, E.(1);
(1)Theradiag, Research and Development, Marne la Vallée Cedex 2, France;(2)Theradiag, Theranostics, Marne la Vallée Cedex 2, France
P093: COVID-19 lockdown and mental health burden in Inflammatory Bowel Disease paediatric patients: a case-control studyECCO'21 Virtual
Year: 2021
Authors: Milo, F.(1);Romeo, E.F.(2);Rea, F.(2);Grimaldi Capitello, T.(1);De Angelis, P.(2);Tabarini, P.(1);
(1)Bambino Gesù Children's Hospital, Clinical Psychology Unit, Rome, Italy;(2)Bambino Gesù Children's Hospital, Digestive Endoscopy and Surgery Unit, Rome, Italy
P094: Textbook outcome in Inflammatory Bowel Disease surgeryECCO'21 Virtual
Year: 2021
Authors: Burneikis, D.(1);Liska, D.(1);Lipman, J.(1);Valente, M.(1);Gorgun, E.(1);Kessler, H.(1);Hull, T.(1);Sklow, B.(1);Steele, S.(1);Lightner, A.(1);Holubar, S.(1);
(1)Cleveland Clinic, Colorectal Surgery, Cleveland, United States
P095: Initial disease course in a Belgian, prospective inception cohort of patients with inflammatory bowel disease: the PANTHER cohortECCO'21 Virtual
Year: 2021
Authors: Verstockt, S.(1);Glorieus, E.(2);Ukunda, C.(3);Barbaraci, M.(3);Verstockt, B.(1,4);Sabino, J.(1,4);Ferrante, M.(1,4);Geldof, J.(2,5);De Vos, M.(2,5);Laukens, D.(5);Cleynen, I.(6);Vandermeulen, L.(3);Lobatón, T.(2,5);Vermeire, S.(1,4);
(1)KU Leuven, Department of Chronic Diseases- Metabolism and Ageing, Leuven, Belgium;(2)University Hospital of Ghent, Department of Gastroenterology, Ghent, Belgium;(3)Universitair Ziekenhuis Brussel UZ Brussel, Department of Gastroenterology, Brussels, Belgium;(4)University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium;(5)Ghent University, Department of Internal Medicine and Pediatrics, Ghent, Belgium;(6)KU Leuven, Department of Human Genetics, Leuven, Belgium