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P075

Innate immunity in inflammatory bowel disease and colon cancer

Year: 2016
Authors:

E. Lo Presti*1, R. Di Mitri2, F. Dieli1, F. Mocciaro2, G. Pecoraro2, G. Russo2, S. Meraviglia1

1University of Palermo, Central Laboratory of Advanced Diagnosis & Biomedical Research (CLADIBIOR), Department of Biopathology, Palermo, Italy, 2ARNAS Civico-Di Cristina-Benfratelli Hospital, Department of Gastroenterology and Endoscopy, Palermo, Italy

1CIBERehd - Hospital General Universitario de Alicante, Alicante, Spain 2Basel University, Basel, Switzerland

P076

IL-26 genetic polymorphisms impair cytokine response to bacterial DNA translocation and increase anti-TNF consumption in patients with Crohn's disease

Year: 2017
Source:

1CIBERehd - Hospital General Universitario de Alicante, Alicante, Spain 2Basel University, Basel, Switzerland

Authors:

Piñero P.*1, Juanola O.1, Gutiérrez A.1, Zapater P.1, Giménez P.1, Steinert A.2, Sempere L.1, Gonzalez-Navajas J.M.1, Niess J.2, Francés R.1

P076

The role for T-cells in the pathogenesis of Crohn’s disease–associated fistulae

Year: 2016
Authors:

R. Bruckner*, M. Spalinger, G. Rogler, M. Scharl

University Hospital Zurich, Gastroenterology and Hepatology, Zurich, Switzerland

1Janssen Research & Development, LLC, Spring House, United States 2University Hospitals Leuven, Pathology, Leuven, Belgium

P077

Histological remission in ulcerative colitis: an analysis of two independent cohorts

Year: 2017
Source:

1Janssen Research & Development, LLC, Spring House, United States 2University Hospitals Leuven, Pathology, Leuven, Belgium

Authors:

Li K.*1, Strauss R.1, Marano C.1, Greenbaum L.1, Brodmerkel C.1, De Hertogh G.2

P077

The efficacy of tyrosine kinase inhibitor dasatinib on colonic mucosal damage in murine model of colitis

Year: 2016
Authors:

G. Can*1, S. Ayvaz2, H. Can3, I. Karaboğa4, S. Demirtaş4, H. Akşit5, B. Yilmaz6, U. Korkmaz7, M. Kurt7, T. Karaca4

1Abant Izzet Baysal University, Faculty of Medicine, Department of Gastroenterology, Bolu, Turkey, 2Trakya University, Faculty of Medicine, Department of Paediatric Surgery, Edirne, Turkey, 3Abant Izzet Baysal University, Faculty of Medicine, Department of Internal Medicine, Bolu, Turkey, 4Trakya University, Faculty of Medicine, Department of Histology and Embryology, Edirne, Turkey, 5Balikesir University, Faculty of Veterinary, Balikesir, Turkey, 6Selcuk University, Faculty of Medicine, Department of Gastroenterology, Konya, Turkey, 7Abant Izzet Baysal University, Medical Faculty, Department of Gastroenterology, Bolu, Turkey

1Rega Institute for Medical Research, KU Leuven, Department of Microbiology and Immunology, Laboratory of Immunobiology, Leuven, Belgium 2KU Leuven, Department of Clinical and Experimental Medicine, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium 3Rega Institute for Medical Research, KU Leuven, Department of Microbiology and Immunology, Laboratory of Molecular Bacteriology, Leuven, Belgium 4University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium

P078

Gut microbiome profiling of MMP-9 deficient mice and their wild-type littermates in a model of acute DSS-induced colitis

Year: 2017
Source:

1Rega Institute for Medical Research, KU Leuven, Department of Microbiology and Immunology, Laboratory of Immunobiology, Leuven, Belgium 2KU Leuven, Department of Clinical and Experimental Medicine, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium 3Rega Institute for Medical Research, KU Leuven, Department of Microbiology and Immunology, Laboratory of Molecular Bacteriology, Leuven, Belgium 4University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium

Authors:

de Bruyn M.*1,2, Sabino J.2, Vandeputte D.3, Vermeire S.2,4, Raes J.3, Opdenakker G.1

P078

Walnut extract ameliorates acute and chronic colitis in murine models of colitis

Year: 2016
Authors:

S.-J. Koh*, K. L. Lee, J.W. Kim, B. G. Kim, Y. J. Jung

Seoul National University Boramae Hospital, Seoul National University College of Medicine, Internal Medicine, Seoul, South Korea

1University of Birmingham, Institute of Cancer and Genomic Sciences, Birmingham, United Kingdom 2University Hospital Birmingham, Department of Gastroenterology, Birmingham, United Kingdom 3University of Birmingham, Institute of Microbiology and Infection, Birmingham, United Kingdom 4University of Birmingham, Centre for Liver Research and National Institute of Health Research (NIHR) Birmingham, Liver Biomedical Research Unit (BRU), Institute of Immunology and Immunotherapy, Birmingham, United Kingdom 5Oslo University Hospital Rikshospitalet, University of Oslo, Norwegian PSC Research Center and Institute of Clinical Medicine, Oslo, Norway 6Kings College London, Twin Research & Genetic Epidemiology, London, United Kingdom 7University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom 8University Hospital Birmingham, Institute of Translational Medicine, Birmingham, United Kingdom

P079

Association of gut microbiota with mucosal inflammation in ulcerative colitis

Year: 2017
Source:

1University of Birmingham, Institute of Cancer and Genomic Sciences, Birmingham, United Kingdom 2University Hospital Birmingham, Department of Gastroenterology, Birmingham, United Kingdom 3University of Birmingham, Institute of Microbiology and Infection, Birmingham, United Kingdom 4University of Birmingham, Centre for Liver Research and National Institute of Health Research (NIHR) Birmingham, Liver Biomedical Research Unit (BRU), Institute of Immunology and Immunotherapy, Birmingham, United Kingdom 5Oslo University Hospital Rikshospitalet, University of Oslo, Norwegian PSC Research Center and Institute of Clinical Medicine, Oslo, Norway 6Kings College London, Twin Research & Genetic Epidemiology, London, United Kingdom 7University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom 8University Hospital Birmingham, Institute of Translational Medicine, Birmingham, United Kingdom

Authors:

Quraishi M.N.*1,2, Rossiter A.3, Chung B.4,5, Beaumont M.6, Liaskou E.4, Horniblow R.1, Beggs A.1, Withers D.7, Ghosh S.2,8, Tselepis C.1, Hirschfield G.4, Iqbal T.H.1,2

P079

Trehalose ameliorates colitis by increasing mucosal autophagy and M2 polarisation

Year: 2016
Authors:

J. Cosin-Roger*1, D. Ortiz-Masia1, D. C. Macias-Ceja2, P. Salvador1, L. Gisbert-Ferrandiz1, C. Hernandez2, S. Calatayud1, M. D. Barrachina1

1University of Valencia, Valencia, Spain, 2Fisabio Hospital Peset, Valencia, Spain

1Index Pharmaceuticals, Stockholm, Sweden 2University of Erlangen-Nürnberg, Department of Medicine 1, Erlangen, Germany

P080

IL-10 induction properties of the TLR-9 agonist cobitolimod – a candidate for treatment of active ulcerative colitis in late stage of clinical development

Year: 2017
Source:

1Index Pharmaceuticals, Stockholm, Sweden 2University of Erlangen-Nürnberg, Department of Medicine 1, Erlangen, Germany

Authors:

Admyre C.1, Zargari A.1, Atreya R.2, Knittel T.*1

P080

Modulation of T-cell glycosylation and the control of intestinal inflammation

Year: 2016
Authors:

A. M. Dias*1, 2, A. Correia3, M. Pereira1, C. R. Almeida4, M. Lima5, 6, R. Marcos-Pinto2, 7, 8, M. Vilanova2, 3, C. A. Reis1, 2, 9, P. Lago8, 
S. S. Pinho1, 2

1Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) & i3S – Instituto de Investigação e Inovação em Saúde, Glycobiology in Cancer, Porto, Portugal, 2Institute of Biomedical Sciences of Abel Salazar (ICBAS), University of Porto, Porto, Portugal, 3Instituto de Investigação e Inovação em Saude (I3S)/Institute for Molecular and Cell Biology (IBMC), Immunobiology Group, Porto, Portugal, 4Instituto de Investigação e Inovação em Saude (I3S)/ Institute of Biomedical Engineering (INEB), NEWTherapies Group, University of Porto, Porto, Portugal, 5Centro Hospitalar do Porto , Multidisciplinary Unit for Biomedical Research (UMIB), Porto, Portugal, 6Centro Hospitalar do Porto, Haematology Department, Porto, Portugal, 7Medical Faculty, Centre for Research in HealthTechnologies and Information Systems (CINTESIS), Porto, Portugal, 8Centro Hospitalar do Porto, Department of Gastroenterology, Porto, Portugal, 9University of Porto, Medical Faculty, Porto, Portugal

Royal College of Physicians, Clinical Effectiveness and Evaluation Unit, London, United Kingdom

P081

10 years of the UK Inflammatory Bowel Disease (IBD) Audit and the journey is just beginning

Year: 2017
Source:

Royal College of Physicians, Clinical Effectiveness and Evaluation Unit, London, United Kingdom

Authors:

Protheroe A., Murray S.

P081

Evaluation of intestinal permeability with a triple sugar test in inflammatory bowel disease

Year: 2016
Authors:

D. Mukhametova1, D. Abdulganieva*1, S. Koshkin2, S. Abdulhakov1, A. Odintsova3

1Kazan State Medical University, Kazan, Russian Federation, 2Kazan (Volga region) Federal University, Kazan, Russian Federation, 3Republican Clinical Hospital, Kazan, Russian Federation

1Edinburgh Napier University, Edinburgh, United Kingdom 2Royal Hospital For Sick Children, Department of Pediatric Gastroenterology, Edinburgh, United Kingdom 3University Of Edinburgh, Department of Child Life and Health, Edinburgh, United Kingdom

P082

An investigation of azathioprine on autophagy pathway activity

Year: 2017
Source:

1Edinburgh Napier University, Edinburgh, United Kingdom 2Royal Hospital For Sick Children, Department of Pediatric Gastroenterology, Edinburgh, United Kingdom 3University Of Edinburgh, Department of Child Life and Health, Edinburgh, United Kingdom

Authors:

Hooper K.*1, Barlow P.1, Henderson P.2,3, Stevens C.1

P082

Anti-TNF-alpha therapy and apoptosis

Year: 2016
Authors:

R. Zaharie1, F. Zaharie2, A. Tantau*3, B. Petrushev4, M. Tantau4

1University of Medicine and Pharmacy, Third Medical Clinic, Cluj-Napoca, Romania, 2University of Medicine and Pharmacy, Third Surgery Clinic, Cluj-Napoca, Romania, 3University of Medicine and Pharmacy, Fourth Medical Clinic, Cluj-Napoca, Romania, 4University of Medicine and Pharmacy, Third Medical Clinic, Cluj-Napoca, Romania

P083

Intestinal fatty acid binding protein as a biomarker of intestinal damage in children with coeliac and Crohn’s disease

Year: 2016
Authors:

C. M. Clark*1, A. Kountouri1, M. MacKinder1, R. Hansen2, R. K. Russell2, K. Gerasimidis1

1University of Glasgow, Human Nutrition, School of Medicine, Glasgow, United Kingdom, 2Royal Hospital for Children, Department of Paediatric Gastroenterology, Glasgow, United Kingdom

1Peking Union Medical College Hospital, Gastroenterology, Beijing, China 2Cancer Hospital Chinese Academy of Medical Sciences, Beijing, China

P083

The protective role of vitamin D3 on colitis-associated colorectal cancer in a mouse model

Year: 2017
Source:

1Peking Union Medical College Hospital, Gastroenterology, Beijing, China 2Cancer Hospital Chinese Academy of Medical Sciences, Beijing, China

Authors:

Ma L.*1, Xin Y.1, Lv H.1, Wang H.2, Qian J.1

P084

Intestinal organoids derived from patients with inflammatory bowel disease show unaltered transcriptional profiles when compared with healthy controls

Year: 2016
Authors:

M. Noben*1, 2, N. Hendriks1, 2, G. Van Assche1, S. Vermeire1, C. Verfaillie2, M. Ferrante1

1KU Leuven, Translational Research Centre for Gastrointestinal Disorders (Targid), Leuven, Belgium, 2KU Leuven, Stem Cell Institute Leuven, Leuven, Belgium

1University of Trieste, Department of Medicine, Surgery and Health Sciences, Trieste, Italy 2University of Trieste, PhD School in Science of Reproduction and Development, Trieste, Italy 3University of Trieste, Department of Life Sciences, Trieste, Italy 4Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, Trieste, Italy

P084

Investigation of non-coding RNAs as molecular markers during glucocorticoid treatment in children with inflammatory bowel disease

Year: 2017
Source:

1University of Trieste, Department of Medicine, Surgery and Health Sciences, Trieste, Italy 2University of Trieste, PhD School in Science of Reproduction and Development, Trieste, Italy 3University of Trieste, Department of Life Sciences, Trieste, Italy 4Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, Trieste, Italy

Authors:

Lucafò M.*1, Di Silvestre A.2, Romano M.3, Martelossi S.4, Naviglio S.2, Tommasini A.4, Stocco G.3, Ventura A.1,4, Decorti G.1,4, De Iudicibus S.4

P085

Altered proportions of myeloid and plasmacytoid dendritic cells in children with inflammatory bowel disease

Year: 2016
Authors:

M. F. Elshal1, 2, 3, 4, A. M. Aldahlawi2, 3, 5, O. I. Saadah*6, 7, J. P. McCoy8

1Facuty of Sciences, King Abdulaziz Uinversity, Biochemistry Department, Jeddah, Saudi Arabia, 2Inflammatory Bowel Disease Research Group, King Abdulaziz University, Jeddah, Saudi Arabia, 3Immunology Unit, King Fahd Medical Research Centre, Jeddah, Saudi Arabia, 4Sadat City University, Molecular Biology Department, Genetic Engineering and Biotechnology Research Institute, Cairo, Egypt, 5Faculty of Sciences, KIng Abdulaziz University, Biological Sciences Department, Jeddah, Saudi Arabia, 6Faculty of Medicine, King Abdulaziz University, Paediatric Department, Jeddah, Saudi Arabia, 7Inflammatory Bowel Disease Research Group, King Abdulaziz Uinversity, Jeddah, Saudi Arabia, 8National Heart, Lung, and Blood Institute, National Institutes of Health, Flow Cytometry Core, Bethesda, MD, United States

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