P111: Efficacy of a novel long-acting lipidated interleukin-22, alone and in combination with anti-TNF treatment, in a murine chronic DSS colitis modelECCO’23 CopenhagenYear: 2023
Authors: Van De Bunt, M.(1)*;D'Alessio, S.(2);Norrild, J.C.(3);Kjølbye, A.L.(1);Jorgensen, R.(1);
(1)Cytoki Pharma, Research & Development, Hellerup, Denmark;(2)PhoenixLAB srls, Research, Lodi, Italy;(3)Cytoki Pharma, CMC & Quality, Hellerup, Denmark;
P112: S1PR expression on circulating immune cells is not limited to lymphocytes in patients with inflammatory bowel diseaseECCO’23 CopenhagenYear: 2023
Authors: Verstockt., B.(1,2)*;Verstockt, S.(2);Cremer, J.(3);Sabino, J.(1,2);Ferrante, M.(1,2);Vermeire, S.(1,2);
(1)University Hospitals Leuven, Dpt. Gastroenterology and Hepatology, Leuven, Belgium;(2)KU Leuven, Dpt. Chronic Diseases and Metabolism, Leuven, Belgium;(3)KU Leuven, Department of Microbiology- Immunology and Transplantation- Allergy and Clinical Immunology, Leuven, Belgium;
P113: Protein fingerprint biomarkers of collagen remodeling can evaluate fibrogenesis in an in vitro colonic scar-in-a-jar modelECCO’23 CopenhagenYear: 2023
Authors: Pehrsson, M.(1)*;Sorokina Alexdottir, M.(1);Asser Karsdal, M.(2);Høg Mortensen, J.(1);
(1)Nordic Bioscience A/S, Gastroenterology, Herlev, Denmark;(2)Nordic Bioscience A/S, Biomarkers and Research, Herlev, Denmark;
P114: Increased serum levels of the migraine biomarker calcitonin gene related peptide alpha in a newly diagnosed inflammatory bowel disease population: a new mediator for the gut-brain-axisECCO’23 CopenhagenYear: 2023
Authors: Pascual, M.(1)*;Gárate, G.(2);Serrano, M.S.(3);García García, M.J.(1);Castro, B.(3);González Quintanilla, V.(2);Crespo, J.(1);Rivero, M.(1);Pascual, J.(2);
(1)Marqués de Valdecilla University Hospital- Universidad de Cantabria- Instituto de Investigación Valdecilla IDIVAL, Gastroenterology and Hepatology, Santander, Spain;(2)Marqués de Valdecilla University Hospital- Universidad de Cantabria- Instituto de Investigación Valdecilla IDIVAL, Neurology, Santander, Spain;(3)Marqués de Valdecilla University Hospital- Instituto de Investigación Valdecilla IDIVAL, Gastroenterology and Hepatology, Santander, Spain;
P116: RIPK3 - a new marker for assessment of ulcerative colitis severityECCO’23 CopenhagenYear: 2023
Authors: Panayotova, E.(1)*;Atanassova, A.(2);
(1)Medical University of Varna- University Hospital St.Marina - Varna- Bulgaria, Department of Propedeutics of Internal Diseases, Varna, Bulgaria;(2)Medical University of Varna- University Hospital St.Marina - Varna- Bulgaria, Department of Anatomy and Cell Biology, Varna, Bulgaria;
P117: Low-Intensity Pulsed Ultrasound as a new approach of gut disruptive liquid biopsy to boost the release of mucosal extracellular vesicles in Ulcerative ColitisECCO’23 CopenhagenYear: 2023
Authors: Pineda Chavez, S.E.(1,2)*;Rizzo, G.(1,2);Cafarelli, A.(3,4);Sorriento, A.(3,4);Loy, L.(5);dal Buono, A.(5);Gabbiadini, R.(5);Meanti, L.(2);Allocca, M.(6);Danese, S.(6);Repici, A.(1,7);Armuzzi, A.(1,8);Ricotti, L.(3,4);Vetrano, S.(1,2);
(1)Humanitas University, Biomedical Sciences, Pieve Emanuele Mi, Italy;(2)IRCCS Humanitas Research Hospital, Gastroenterology- Laboratory of Gastrointestinal Immunopathology, Rozzano Mi, Italy;(3)Scuola Superiore Sant'Anna, The BioRobotics Institute, Pisa, Italy;(4)Scuola Superiore Sant'Anna, Excellence in Robotics & AI, Pisa, Italy;(5)Humanitas Clinical and Research Center - IRCCS -, IBD Unit- Department of Gastroenterology, Rozzano- Mi, Italy;(6)IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele, Gastroenterology and Endoscopy, Milan, Italy;(7)Humanitas Clinical and Research Center-IRCCS, Endoscopy Unit- Biomedical Sciences, Rozzano Mi, Italy;(8)Humanitas Clinical and Research Center - IRCCS -, IBD Unit- Department of Gastroenterology, Rozzano Mi, Italy;
P118: Induction of ETS1 and senescence associated secretory phenotype in human intestinal fibroblastsECCO’23 CopenhagenYear: 2023
Authors: Seco-Cervera, M.(1)*;Argilés-Alberola, D.(2);Bauset, C.(2);Lis-López, L.(1);Coll, S.(2);Cosín-Roger, J.(1);Ortiz-Masià, D.(2);Calatayud, S.(2);Barrachina, M.D.(2);
(1)Hospital Dr Peset- FISABIO- Valencia- Spain., Dept. Pharmacology. School of Medicine and Dentistry. University of Valencia, Valencia, Spain;(2)Faculty of Medicine - University of Valencia, Pharmacology, Valencia, Spain;
P120: Development and validation of a dedicated score to assess transmural response and transmural healing in patients with Crohn's disease : final results of the DEVISE-CD projectECCO’23 CopenhagenYear: 2023
Authors: Buisson, A.(1)*;Junda, J.(2);Vignette, J.(1);Lecoq, E.(1);Bouguen, G.(3);Pereira, B.(4);Hordonneau, C.(2);
(1)CHU Clermont-Ferrand, IBD Unit, Clermont-Ferrand, France;(2)CHU Clermont-Ferrand, Radiology department, Clermont-Ferrand, France;(3)CHU Rennes, IBD Unit, Rennes, France;(4)CHU Clermont-Ferrand, Biostatistics Unit, Clermont-Ferrand, France;
P121: Clinicomic profiles new feature patterns based on a simplified location classification for Crohn's diseaseECCO’23 CopenhagenYear: 2023
Authors: Hu, W.(1)*;Liang, X.(2);Luo, J.(1);Li, P.(1);Shen, K.(3);Li, J.(4);Li, S.(5);Xin, J.(1);Jiang, J.(1);Shi, D.(1);Wang, X.(6);Xu, D.(6);Yu, Q.(6);Zhang, H.(6);Zhang, X.(7);Song, X.(8);Guo, H.(8);Ge, Q.(9);Chen, Y.(9);Chen, X.(10);Chen, Y.(6);Li, J.(1);
(1)The First Affiliated Hospital- Zhejiang University School of Medicine, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China;(2)Taizhou Central Hospital Taizhou University Hospital, Precision Medicine Center, Taizhou, China;(3)The Second Affiliated Hospital- Zhejiang University School of Medicine, Department of Radiology, Hangzhou, China;(4)Zhejiang Provincial People's Hospital, Department of Gastroenterology, Hangzhou, China;(5)The Second Affiliated Hospital- Zhejiang University School of Medicine, Department of Nursing, Hangzhou, China;(6)The Second Affiliated Hospital- Zhejiang University School of Medicine, Department of Gastroenterology, Hangzhou, China;(7)Nanjing Drum Tower Hospital- Affiliated Drum Tower Hospital- Medical School of Nanjing University, Department of Gastroenterology, Nanjing, China;(8)Chongqing General Hospital, Department of Gastroenterology, Chongqing, China;(9)Huadong Hospital Affiliated to Fudan University, Department of Gastroenterology, Shanghai, China;(10)Zhejiang University School of Medicine, Institute of Pharmaceutical Biotechnology and the First Affiliated Hospital Department of Radiation Oncology, Hangzhou, China;
P122: External validation of the Picasso Histological Remission Index (PHRI) to assess endoscopic and histological remission and predict long-term outcome in Ulcerative Colitis: A multicentre prospective study.ECCO’23 CopenhagenYear: 2023
Authors: ParigiMD, T.L.(1)*;Cannatelli, R.(2);Nardone, O.M.(3);Zammarchi, I.(4);Shivaji, U.(1);Furfaro, F.(5);Zardo, D.(6);Spaggiari, P.(7);Del Sordo, R.(8);Setti, O.(9);Majumder, S.(1);Smith, S.C.L.(1);Ghosh, S.(10);Danese, S.(5);Armuzzi, A.(11);Villanacci, V.(9);Iacucci, M.(1);
(1)University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom;(2)ASST Fatebenefratelli Sacco, Gastroenterology Unit, Milan, Italy;(3)University of Naples Federico II, Gastroenterology- Department of public health, Naples, Italy;(4)ASST-Spedali Civili Brescia, Gastroenterology Unit, Brescia, Italy;(5)IRCCS Ospedale San Raffaele, Department of Gastroenterology and Digestive Endoscopy, Milan, Italy;(6)University Hospitals Birmingham NHS Foundation Trust, Department of Histopathology, Birmingham, United Kingdom;(7)IRCCS Humanitas Research Hospital, Pathology Unit, Milan, Italy;(8)Medical School- University of Perugia, Department of Medicine and Surgery- Section of Anatomic Pathology and Histology, Perugia, Italy;(9)ASST-Spedali Civili Brescia, Institute of Pathology, Brescia, Italy;(10)University College of Cork, APC Microbiome Ireland- College of Medicine and Health, Cork, Ireland;(11)IRCSS Humanitas Research Hospital, IBD Center- Department of Gastroenterology, Milan, Italy;
P123: Development of an end-to-end Mayo endoscopic score machine learning algorithm for use in clinical trials of ulcerative colitisECCO’23 CopenhagenYear: 2023
Authors: Vieira, M.(1)*;Mishkin, D.S.(2);Gaither, K.W.(3);Safran, M.(4);Dashuta, A.(4);Tarakanov, A.(4);Zfira, L.(4);Fuerst, T.(5);
(1)Clario Inc., Medical and Scientific Affairs, Cleveland, United States;(2)Atrius Health, Gastroenterology, Boston, United States;(3)Clario Inc., Medical and Scientific Affairs, Portland, United States;(4)RSIP VIsion, Research and Development, Jerusalem, Israel;(5)Clario Inc., Medical & Scientific Affairs, San Mateo, United States;
P124: Risk of surgery in inflammatory bowel disease: A systematic review and meta-analysis of sex-based differencesECCO’23 CopenhagenYear: 2023
Authors: Rasmussen, N.F.(1)*;Gregersen , L.H.K.(1);Hikmat, Z.(2);Moos, C.M.(3);Green, A.(4);Andersen, V.(1);Madsen, G.I.(5);Jess, T.(6);Kjeldsen, L.J.(7);
(1)University Hospital of Southern Jutland, Research Unit of Molecular Diagnostics and Clinical Research, Aabenraa, Denmark;(2)University Hospital pf Southern Jutland, Research Unit of Molecular Diagnostics and Clinical Research, Aabenraa, Denmark;(3)University Hospital of Southern Jutland, Department of Clinical Research, Aabenraa, Denmark;(4)Odense University Hospital, Department of Clinical Research, Odense, Denmark;(5)Odense University Hospital, Department of Clinical Pathology, Odense, Denmark;(6)National Center of Excellence for Molecular Prediction of Inflammatory Bowel Disease- PREDICT, Department of Clinical Medicine- Faculty of Medicine- Aalborg University, Copenhagen, Denmark;(7)University Hospital of Southern Jutland, Department of Hospital Pharmacy, Aabenraa, Denmark;
P125: LCI/BLI chromoendoscopy plus CAD-EYE artificial intelligence for the detection and characterization of endoscopic visible lesions in ulcerative colitisECCO’23 CopenhagenYear: 2023
Authors: Cassinotti, A.(1)*;Zadro, V.(1);Parravicini, M.(1);Ferraris, M.(1);Balzarini, M.(1);Sessa, F.(2);La Rosa, S.(2);Segato, S.(1);Cortelezzi, C.C.(1);Segato, S.(1);
(1)ASST Sette Laghi, Gastroenterology and Digestive Endoscopy Unit, Varese, Italy;(2)ASST Sette Laghi, Pathology Unit, Varese, Italy;
P126: Ask twice: The importance of repeated faecal calprotectin testing prior diagnostic colonoscopy in an adult inception cohort.ECCO’23 CopenhagenYear: 2023
Authors: Rimmer, P.(1)*;Cheesbrough, J.(1);Quraishi, M.N.(1);Sharma, N.(1);Cooney, R.(1);Love, M.(1);Iqbal, T.(1);
(1)University Hospitals Birmingham NHS Foundation Trust, Gastroenterology, Birmingham, United Kingdom;
P127: Inflammatory Bowel Disease-associated colorectal cancers: retrospective cohort study from a tertiary centre surveillance programme over 10 yearsECCO’23 CopenhagenYear: 2023
Authors: Porter, R.(1,2)*;Gillespie, S.L.(1);Song, M.(1,2);Ball, G.(3);Crawford, A.(1);Churchhouse, A.(1,2);Gardner, M.(1);Plevris, N.(1,2);Chuah, C.S.(1,2);Brindle, W.(1);Watson, E.(1);Jenkinson, P.(4);Fulforth, J.(1);Kedziora, M.(1);Dickson, B.(1);Megan, A.(1);Jones, G.R.(1,2);Din, S.(1,2);
(1)Edinburgh IBD Unit- Department of Gastroenterology, Western General Hospital- NHS Lothian, Edinburgh, United Kingdom;(2)Deanery of Clinical Sciences, University of Edinburgh, Edinburgh, United Kingdom;(3)Edinburgh Cancer Centre, Western General Hospital- NHS Lothian, Edinburgh, United Kingdom;(4)Department of Colorectal Surgery, Western General Hospital- NHS Lothian, Edinburgh, United Kingdom;
P128: The role of small bowel capsule endoscopy as a diagnostic tool in isolated complex perianal diseaseECCO’23 CopenhagenYear: 2023
Authors: Avni Biron, I.(1)*; Ollech, J.E.(1);Toth , E.(2);Nemet, A.(2); Wurm Johansson, G.(2);Schweinstein, H.(1); Kopylov , U.(3);Margalit Yehuda , R.(3);Dotan, I.(1);Yanai, H.(1);
(1)Rabin medical center, Division of gastroenterology, Petah Tikva, Israel;(2)Skåne University Hospital- Lund University, Department of Gastroenterology, Malmo, Sweden;(3)Sheba medical center, Institute of Gastroenterology, Tel Hashomer, Israel;
P129: Intestinal ultrasound at week 12 predicts long-term endoscopic response to biologics in ulcerative colitisECCO’23 CopenhagenYear: 2023
Authors: Allocca, M.(1)*;Dell'Avalle, C.(2);Furfaro, F.(3);Zilli, A.(3);Radice, S.(3);D'Amico, F.(3);Peyrin-Biroulet, L.(4);Fiorino, G.(3);Danese, S.(3);
(1)IRCCS San Raffaele Hospital, Gastroenterology and Endoscopy, Milan, Italy;(2)Humanitas University, Department of Biomedical Sciences, Milan, Italy;(3)IRCCS San Raffaele Hospital, Gastroenterology and Endoscopy, Milan, Italy;(4)Nancy University Hospital, Inserm- NGERE, Nancy, France;
P130: Intestinal ultrasound combined to fecal calprotectin is effective to predict endoscopic mucosal healing in ulcerative colitis: a cross-sectional studyECCO’23 CopenhagenYear: 2023
Authors: Yzet, C.(1);Meudjo, E.(1);Moreau, C.(1);Brazier, F.(1);Hautefeuille, V.(1);Decrombecque, C.(1);Sarba, R.(1);Pichois, R.(2);Meynier, J.(3);Fumery, M.(1)*;
(1)CHU Amiens Picardie, Gastroenterology, Amiens, France;(2)CHU Amiens Picardie, Radiology, Amiens, France;(3)CHU Amiens Picardie, Biostatistics, Amiens, France;