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P045

The relationship between thiol/disulphide and inflammatory bowel disease

Year: 2016
Authors:

H. Akinci*1, Y. Coskun1, O. Erel2, M. Hamamci1, F. Karaahmet1, S. Kilincalp1, M. Alisik2, I. Yuksel1, 3

1Diskapi Yildirim Beyazit Education and Research Hospital, Gastroenterology, Ankara, Turkey, 2Yildirim Beyazit University School of Medicine, Biochemistry, Ankara, Turkey, 3Yildirim Beyazit University School of Medicine, Gastroenterology, Ankara, Turkey

1Tel Aviv Medical Center, IBD unit, Department of Gastroenterology and hepatology, Tel Aviv, Israel 2Sackler Faculty of Medicine, Tel Aviv Israel, IBD Center, Department of Gastroenterology and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 3Tel Aviv Medical Center, IBD Center, Department of Gastroenterology and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 4Sackler Faculty of Medicine, Tel Aviv Israel, Department of Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 5Tel Aviv Medical Center, Tel Aviv Israel, Pouch Clinic, IBD Center, Tel Aviv, Israel

P046

Starch consumption is associated with serologic responses in patients with ulcerative colitis and an ileo-anal pouch

Year: 2017
Source:

1Tel Aviv Medical Center, IBD unit, Department of Gastroenterology and hepatology, Tel Aviv, Israel 2Sackler Faculty of Medicine, Tel Aviv Israel, IBD Center, Department of Gastroenterology and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 3Tel Aviv Medical Center, IBD Center, Department of Gastroenterology and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 4Sackler Faculty of Medicine, Tel Aviv Israel, Department of Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 5Tel Aviv Medical Center, Tel Aviv Israel, Pouch Clinic, IBD Center, Tel Aviv, Israel

Authors:

Goren I.1,2, Godny L.2,3, Maharshak N.3,4, Tulchinsky H.4,5, Dotan I.*2,5

P046

Therapeutic effects of mouse bone marrow–derived single clonal mesenchymal stem cells in a mouse model of inflammatory bowel disease

Year: 2016
Authors:

K. B. Hahm*1, S. U. Song2, S. H. Park3

1CHA University, Gastroenterology, Seongnam, South Korea, 2Inha University, Gastroenterology, Incheon, South Korea, 3Sungkyunkwan University, Ciological Science, Suwon, South Korea

P047

Enterocytes and dendritic cells both contribute to the intestinal inflammation in paediatric inflammatory bowel diseases

Year: 2016
Authors:

C. Strisciuglio*1, S. Vitale2, L. Pisapia3, E. Miele4, P. Barba3, A. Vitale1, S. Cenni4, G. Del Pozzo3, R. Troncone4, A. Staiano4, C. Gianfrani2

1Second University of Naples, Department of Woman, Child and General and Specialised Surgery, Naples, Italy, 2Institute of Protein Biochemistry, CNR, Naples, Italy, 3Institute of Genetics and Biophysics Adriano Buzzati Traverso, CNR, Naples, Italy, 4University Federico II, Department of Translational Medical Science, Section of Paediatrics, Naples, Italy

Gilead Sciences, Inc, Foster City, United States

P047

Therapeutic dosing of filgotinib (GS-6034, GLPG0634) is efficacious in the mouse DSS model of colitis

Year: 2017
Source:

Gilead Sciences, Inc, Foster City, United States

Authors:

Kim S., Zheng J., Lu B., Alonzo D., Kanwar B., Smith V.

P048

Cigarette smoke impairs intestinal epithelial cell polarity development and morphogenesis

Year: 2016
Authors:

L. J. Klunder*1, T. Blokzijl2, R. Ferreira1, K.-N. Faber2, G. Dijkstra2, S. C. D. van IJzendoorn1

1University Medical Centre Groningen, Department of Cell Biology, Groningen, Netherlands, 2University Medical Centre Groningen, Department of Gastroenterology and Hepatology, Groningen, Netherlands

1Linköping University, Department of Clinical and Experimental Medicine, Linköping, Sweden 2University Hospital, Dept of Gastroenterology, Linköping, Sweden

P048

Decreased expression of aquaporins in colonic biopsies from collagenous colitis patients. A novel diarrhoeal pathomechanism?

Year: 2017
Source:

1Linköping University, Department of Clinical and Experimental Medicine, Linköping, Sweden 2University Hospital, Dept of Gastroenterology, Linköping, Sweden

Authors:

Holm A.1, Mancebo Giménez A.1, Loitto V.1, Vikström E.1, Magnusson K.-E.1, Münch A.*2

Centro Hospitalar São João, Department of Gastroenterology, Porto, Portugal

P049

Lewis score: a useful tool for the diagnosis but not for the definition of prognosis in suspected Crohn's disease

Year: 2017
Source:

Centro Hospitalar São João, Department of Gastroenterology, Porto, Portugal

Authors:

Silva M., Cardoso H., Peixoto A., Marques M., Rodrigues-Pinto E., Nunes A.C.-R., Lopes S., Magro F., Macedo G.

P049

Prevalence and factors associated with vitamin D deficiency in patients with inflammatory bowel disease on biologic therapies

Year: 2016
Authors:

K. Sugrue, D. Fitzgerald, M. Buckley, J. McCarthy, D. Farrell*

Mercy University Hospital, Department of Gastroenterology, Cork, Ireland

1Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands 2Robarts Clinical Trials, Inc., Amsterdam, Netherlands 3Robarts Clinical Trials, Inc., London, Canada 4Mount Sinai Hospital, Toronto, Canada 5F. Widjaja Foundation Inflammatory Bowel and Immunobiology Institute, Los Angeles, United States 6Humanitas University, Milan, Italy 7Academic Medical Center, Amsterdam, Canada 8University of California, San Diego, United States 9Mayo Clinic, Rochester, United States 10University of Leuven, Leuven, Belgium 11Hospital Clínic Barcelona, Barcelona, Spain 12Robarts Clinical Trials, Inc., San Diego, United States 13University of Western Ontario, London, Canada

P050

Centrally-determined standardization of flow cytometry methods reduces inter-laboratory variation in a prospective multicenter study

Year: 2017
Source:

1Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands 2Robarts Clinical Trials, Inc., Amsterdam, Netherlands 3Robarts Clinical Trials, Inc., London, Canada 4Mount Sinai Hospital, Toronto, Canada 5F. Widjaja Foundation Inflammatory Bowel and Immunobiology Institute, Los Angeles, United States 6Humanitas University, Milan, Italy 7Academic Medical Center, Amsterdam, Canada 8University of California, San Diego, United States 9Mayo Clinic, Rochester, United States 10University of Leuven, Leuven, Belgium 11Hospital Clínic Barcelona, Barcelona, Spain 12Robarts Clinical Trials, Inc., San Diego, United States 13University of Western Ontario, London, Canada

Authors:

Westera L.1, van Viegen T.2, Jeyarajah J.3, Azad A.4, Bilsborough J.5, van den Brink G.1, Danese S.6, D'Haens G.2,7, Eckmann L.8, Faubion W.9, Korf H.10, McGovern D.5, Panes J.11, Salas A.11, Sandborn W.8,12, Silverberg M.4, Smith M.4, Vermeire S.10, Vetrano S.6, Shackelton L.3, Stitt L.3, Jairath V.3,13, Levesque B.8,12, Spencer D.3, Feagan B.3,13, Vande Casteele N.*8,12

P050

Proinflammatory action of 5-HT in colon epithelial cell response to gut bacteria through NOX2 induction

Year: 2016
Authors:

J.-A. Kim*, S. Banskota, S. Regmi, P. Grung, B.-S. Jeong, H. W. Chang

Yeungnam University, College of Pharmacy, Gyeongsan, South Korea

P051

Chemokines CXCL17, CCL20, and the receptor CXCR5 are overexpressed in the colonic mucosa from patients with active ulcerative colitis: CXCL17 is a potential marker of histological remission

Year: 2016
Authors:

J. Yamamoto-Furusho*1, E. Iturriaga-Goyon2, G. Fonseca-Camarillo1

1IBD Clinic, Instituto Nacional de Ciencias Medicas y Nutricion, Gastroenterology, Mexico, Mexico, 2Instituto Nacional de Ciencias Medicas y Nutricion, Gastroenterology, Mexico, Mexico

1Beaujon Hospital, Gastroenterology, Clichy, France 2University Paris, Paris, France 3CTMA- Clinical Trials Mobile Application, Paris, France

P051

Use of digital technology to boost patient recruitment in inflammatory bowel disease clinical trials

Year: 2017
Source:

1Beaujon Hospital, Gastroenterology, Clichy, France 2University Paris, Paris, France 3CTMA- Clinical Trials Mobile Application, Paris, France

Authors:

Bouhnik Y.*1, Amiot A.2, Alexandre N.1, Attar A.1, Kondamudi P.K.3, Stéfanescu C.1

P052

Intestinal total bacteria concentration and translocation of bacteria in inflammatory bowel disease

Year: 2016
Authors:

S. Vrakas1, M. Gazouli*2, K. Mountzouris3, G. Michalopoulos1, G. Karamanolis4, G. Papatheodoridis5, C. Tzathas1

1Tzaneion General Hospital, Gastroenterology Department, Piraeus, Greece, 2Medical School, National & Kapodistrian University, Biology, Athens, Greece, 3Agriculture University, Nutritional Physiology and Feeding, Athens, Greece, 4Medical School, National & Kapodistrian University, Gastroenterology Unit, Second University Surgical Department, Athens, Greece, 5Medical School National & Kapodistrian University, Gastroenterology, Athens, Greece

1University of Zurich, Zurich, Switzerland 2Novartis Institute for Biomedical Research, Basel, Switzerland 3University Hospital Zürich, Department of Gastroenterology and Hepatology, Zurich, Switzerland

P052

The role of TDAG8 in intestinal inflammation

Year: 2017
Source:

1University of Zurich, Zurich, Switzerland 2Novartis Institute for Biomedical Research, Basel, Switzerland 3University Hospital Zürich, Department of Gastroenterology and Hepatology, Zurich, Switzerland

Authors:

Tcymbarevich I.1, de Vallière C.*1, Spalinger M.1, Cosin-Roger J.1, Atrott K.1, Richards S.2, Seuwen K.2, Frey-Wagner I.1, Rogler G.1,3

1Royal London Hospital, Gastroenterology, London, United Kingdom 2The Blizard Institute, Centre for Immunobiology, Barts and the London School of Medicine, London, United Kingdom 3The Blizard Institute, Centre for Immunology, Barts and the London School of Medicine, London, United Kingdom

P053

Circulating non-classical monocytes are reduced in patients with active IBD but increase after vedolizumab: a role for α4β7 in myeloid cell recruitment to the inflamed intestine

Year: 2017
Source:

1Royal London Hospital, Gastroenterology, London, United Kingdom 2The Blizard Institute, Centre for Immunobiology, Barts and the London School of Medicine, London, United Kingdom 3The Blizard Institute, Centre for Immunology, Barts and the London School of Medicine, London, United Kingdom

Authors:

Gordon H.*1, Hoti I.2, Lindsay J.O.1,3, Stagg A.2

P053

Histological and immunohistochemical indicators of progression towards malignancy in ulcerative colitis

Year: 2016
Authors:

C. Popp*1, G. Micu1, M. Cioplea1, L. Sticlaru1, G. Pop1, B. Mateescu2, F. Staniceanu1, S. Zurac1, L. Nichita1

1Colentina University Hospital, Pathology, Bucuresti, Romania, 2Colentina University Hospital, Gastroenterology, Bucuresti, Romania

Nanfang Hospital, Southern Medical Universit, Department of Gastroenterology, Guangzhou, China

P054

Metformin protects against intestinal barrier disruption via AMPKα1-dependent inhibition of JNK signaling pathway

Year: 2017
Source:

Nanfang Hospital, Southern Medical Universit, Department of Gastroenterology, Guangzhou, China

Authors:

Deng J., Chen Y., Zeng L.

P054

Soluble GPVI is raised in patients with inflammatory bowel disease and anaemia

Year: 2016
Authors:

S. J. Montague1, A. Chauhan*2, E. E. Gardiner3, R. K. Andrews3, 
S. P. Watson1, T. Iqbal4

1Institute of Biomedical Research, University of Birmingham, Centre for Cardiovascular Sciences, College of Medical and Dental Sciences, Birmingham, United Kingdom, 2Centre for Liver Research, and National Institute of Health Research Birmingham Liver Biomedical Research Unit, Institute of Biomedical Research, College of Medical and Dental Science, Birmingham, United Kingdom, 3Monash University, Australian Centre for Blood Diseases, Melbourne, Australia, 4Queen Elizabeth Hospital, Department of Gastroenterology, Birmingham, United Kingdom

P055

Galectin-3 plays protective roles in intestinal Behçet’s disease

Year: 2016
Authors:

J. H. Kim*1, 2, H. J. Lee1, H. W. Ma1, 2, D. H. Seo1, 2, X. Che1, 2, D. H. Kim1, S. W. Kim1, 2, 3, J. H. Cheon1, 2, 3

1Yonsei University College of Medicine, Department of Internal Medicine and Institute of Gastroenterology, Seoul, South Korea, 2Yonsei University, Brain Korea 21 Plus Project for Medical Science, Seoul, South Korea, 3Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, South Korea

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