P430: The influence of persistent organ damage on IFX pharmacokinetic modeling and disease progression assessment: findings from a prospective real-world study in inflammatory bowel disease patientsECCO'24Year: 2024
Authors: Magro, F.(1,2,3,4,5)*;Fernandes, S.(6,7);Patita, M.(8);Arroja, B.(9);Lago, P.(2,10);Rosa, I.(11);Tavares de Sousa, H.(12,13);Ministro, P.(2,14);Mocanu, I.(8);Vieira, A.(8);Castela, J.(15);Moleiro, J.(15);Roseira, J.(12,13);Cancela, E.(14);Sousa, P.(14);Portela, F.(2,16);Correia, L.(2,17);Moreira, P.(3);Afonso, J.(2);Dias, S.(2);Danese, S.(18,19);Peyrin-Biroulet, L.(20);Vucicevic, K.(21);Santiago, M.(2);
(1)São João Hospital University Center, Gastroenterology Department, Porto, Portugal;(2)Portuguese Group of Studies in Inflammatory Bowel Disease, Gedii, Porto, Portugal;(3)São João Hospital University Center, Clinical Pharmacology Unit, Porto, Portugal;(4)Faculty of Medicine- University of Porto, Centre for Health Technology and Services Research- Health Research Network CINTESIS@RISE, Porto, Portugal;(5)Faculty of Medicine- University of Porto, Department of Biomedicine- Unit of Pharmacology and Therapeutics, Porto, Portugal;(6)Northern Lisbon University Center, Gastroenterology Department, Lisbon, Portugal;(7)Medical University of Lisbon, Clinica Universitária de Gastrenterologia, Lisbon, Portugal;(8)Garcia da Orta Hospital, Gastroenterology Department, Lisbon, Portugal;(9)Braga Hospital, Gastroenterology Department, Braga, Portugal;(10)Porto Hospital University Center, Gastroenterology Department, Porto, Portugal;(11)IPOLFG, Gastroenterology Department, Lisboa, Portugal;(12)Algarve Hospital University Center ‐ Portimão Unit, Gastroenterology Department, Portimão, Portugal;(13)University of Algarve, ABC - Algarve Biomedical Center, Faro, Portugal;(14)Viseu‐Tondela Hospital Center, Gastroenterology Department, Viseu, Portugal;(15)IPOLFG, Gastroenterology Department, Lisbon, Portugal;(16)Coimbra Hospital University Center, Gastroenterology Department, Coimbra, Portugal;(17)Northern Lisbon University Hospital Center, Gastroenterology Department, Lisbon, Portugal;(18)Humanitas University, Department of Biomedical Sciences, Milan, Italy;(19)Humanitas Research Hospital- IRCCS, IBD Center, Milan, Italy;(20)University Hospital of Nancy- University of Lorraine, Department of Gastroenterology and Inserm NGERE U1256, Nancy, France;(21)University of Belgrade, Department of Pharmacokinetics and Clinical Pharmacy, Belgrade, Serbia;
P431: Assessing intestinal barrier healing by fusing ultra-high magnification endoscope and automated spatial multispectral imaging analysis in PSC-colitis patientsECCO'24Year: 2024
Authors: Iacucci, M.(1,2,3)*;Majumder, S.(1,3);Santacroce, G.(1);Zammarchi, I.(1);Maeda, Y.(1);Shivaji, U.N.(2,3);Abdawn, Z.(4);Hejmadi, R.(4);Hayes, B.(5);Crotty, R.(5);Burke, L.(5);Ghosh, S.(1);
(1)APC Microbiome Ireland-College of Medicine and Health, University College of Cork, Cork, Ireland;(2)Gastroenterology-Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom;(3)Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom;(4)Department of Histopathology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom;(5)Department of Histopathology, Cork University Hospital, Cork, Ireland;
P432: Real-time automated assessment of histological disease activity in patients with ulcerative colitis using single wavelength endoscopy technologyECCO'24Year: 2024
Authors: Sinonquel, P.(1,2)*;Lenfant, M.(1,2);Eelbode, T.(3);Callaerts, B.(3);Watanabe, H.(4);Guedelha Sabino, J.P.(1,2);Verstockt, B.(1,2);Maes, F.(3);De Hertogh, G.(5);Vermeire, S.(1,2);Bisschops, R.(1,2);
(1)UZ Leuven, Gastroenterology and Hepatology, Leuven, Belgium;(2)KU Leuven, Translational Research in Gastrointestinal Disorders, Leuven, Belgium;(3)KU Leuven, Electrical Engineering ESAT/PSI, Leuven, Belgium;(4)Fujifilm, Medical Systems R&D Center-, Tokyo, Japan;(5)UZ Leuven, Pathology, Leuven, Belgium;
P433: Short-term outcomes of surgical treatment in primary ileocecal Crohn’s disease patients. Results of Crohn’s(urg) study, multicenter, retrospective, comparative analysis between indications for luminal and complicated phenotype.ECCO'24Year: 2024
Authors: Avellaneda, N.L.(1)*;Pellino, G.(2);Maroli, A.(3);Tottrup, A.(4);Bislenghi, G.(5);Colpaert, J.(5);D@E@Hoore, A.(5);Giorgi, L.(3);Juachon, P.(3);Harsløf, S.(4);de Buck Van Overstraeten, A.(6);Olivera, P.(6);Gomez, J.(6);Holubar, S.(7);Lincango Naranjo, E.(7);Steele, S.(7);Merchea, A.(8);Shacker, A.(8);Marti Gallostra, M.(9);Kraft, M.(9);Kotze, P.G.(10);Yuki Maruyana, B.(10);Wexner, S.(11);Garoufalia, Z.(11);Zhihui, C.(12);Hahnloser, D.(13);Rrupa, D.(13);Buskens, C.(14);Haanappel , A.(15);Warusavitarne, J.(16);Williams, K.(16);Christensen, P.(4);Spinelli, A.(3);
(1)Aarhus University Hospital- Denmark, Colorectal Surgery, Capital Federal, Argentina;(2)Università degli Studi della Campania @D@Luigi Vanvitelli@D@, Advanced Medical and Surgical Sciences, Naples, Italy;(3)Humanitas Research Hospital, Colorectal Surgery, Milan, Italy;(4)Aarhus University Hospital, Colorectal Surgery, Aarhus, Denmark;(5)Leuven University Hospital, Colorectal Surgery, Leuven, Belgium;(6)Sinai Health Hospital, Colorectal Surgery, Toronto, Canada;(7)Cleveland Clinic, Colorectal Surgery, Ohio, United States;(8)Mayo Clinic, Colorectal Surgery, Jacksonville, United States;(9)Vall d@E@Hebron University Hospital, Colorectal Surgery, Barcelona, Spain;(10)Pontifícia Universidade Católica do Paraná PUCPR, Colorectal Surgery, Curitiba, Brazil;(11)Cleveland Clinic, Colorectal Surgery, Florida, United States;(12)Sun Yat-sen University, Colorectal Surgery, China, China;(13)Lausanne University Hospital, Colorectal Surgery, Lausanne, Switzerland;(14)Amsterdam Medical Hospitals, Colorectal Surgery, Amsterdam, The Netherlands;(15)Amsterdam Medical Hospital, Colorectal Surgery, Amsterdam, The Netherlands;(16)San Marks Hospital, Colorectal Surgery, London, United Kingdom;
P434: Incidence of chronic end-stage renal disease in patients with inflammatory bowel disease: a population-based cohort study from the French National Health Insurance Database.ECCO'24Year: 2024
Authors: Prothe, C.(1)*;Boitel, A.(2);Martin, B.(2);Clairet, V.(3);Juif, L.(3);Lang, S.(4);Koch, S.(3);Ducloux, D.(4,5);Desmarets, M.(6,7);Vuitton, L.(3,5);
(1)CHU JMinjoz, service de gastroentérologie, Besancon, France;(2)CHU JMinjoz, Inserm- Centre d’investigation clinique 1431, Besançon, France;(3)CHU JMinjoz, Service de gastroentérologie, Besançon, France;(4)CHU JMinjoz, service de néphrologie, Besançon, France;(5)Université de Franche Comté, EFS- Inserm- UMR Right-, Besançon, France;(6)CHU JMinjoz, Inserm- Centre d’investigation clinique 1431-, Besançon, France;(7)Université de Franche-Comté, EFS- Inserm- UMR Right, Besançon, France;
P435: Plasma inflammation-related proteins as markers of anxiety and depression disorders in inflammatory bowel disease patientsECCO'24Year: 2024
Authors: Zhou, M.S.(1)*;Dang, Y.(1);Xu, F.(1);Xu, C.Y.(1);Wang, Z.(1);Wang, C.S.E.(1);Zhu, S.Y.(1);Li, P.(1);Wu, J.(1);Shi, H.Y.(1);
(1)Capital Medical University- Beijing Friendship Hospital- National Clinical Research Center for Digestive Diseases, Department of gastroenterology, Beijing, China;
P436: The AI based Red Density score is correlated with the established and new histological indices for Ulcerative Colitis in an independent cohort.ECCO'24Year: 2024
Authors: BossuytMD PhD, P.(1)*;Sinonquel, P.(2);John, S.(3);Shivaji, U.(4);Iacucci, M.(5);Nakase, H.(6);Van Aelst, S.(7);Pillai, S.(8);Abdawn, Z.(9);Sugita, S.(10);McCartney, S.(11);Armuzzi, A.(12);Bessissow, T.(13);Rath, T.(14);Yang, D.H.(15);Vermeire, S.(2);De Hertogh, G.(16);Bisschops, R.(2);
(1)Imelda General Hospital, Department of Gastroenterology, Bonheiden, Belgium;(2)UZ Leuven, Department of gastroenterology, Leuven, Belgium;(3)Gold Coast University Hospital, Department of gastroenterology, Gold Coast, Australia;(4)University Hospital Birmingham, Department of gastroenterology, Birmingham, United Kingdom;(5)University Hospital Cork, Department of gastroenterology, Cork, Ireland;(6)Sapporo Medical University, Department of gastroenterology, Sapporo, Japan;(7)Imelda General Hospital, Department of pathology, Bonheiden, Belgium;(8)Gold Coast University Hospital, Department of pathogology, Gold Coast, Australia;(9)University Hospital Birmingham, Department of pathology, Birmingham, United Kingdom;(10)Sapporo Medical University, Department of pathology, Sapporo, Japan;(11)University College London, Department of gastroenterology, London, United Kingdom;(12)Huminatas University Hospital, Department of gastroenterology, Milan, Italy;(13)McGill University Health Center, Department of gastroenterology, Montreal, Canada;(14)University Hospitals Erlangen, Department of gastroenterology, Erlangen, Germany;(15)Asan Medical Center, Department of gastroenterology, Seoul, Korea- Republic Of;(16)UZ Leuven, Department of pathology, Leuven, Belgium;
P437: Feasibility study of a Point-of-Care assay for rapid determination of anti-TNFα biologics in capillary bloodECCO'24Year: 2024
Authors: Ricken, B.(1)*;Brosi, L.(1);Reinhard, C.(2);Anchling, L.(2);Neu, S.(3);Afonso, J.(1);Schuster, T.(4);Wütherich, E.(5);Burri, E.(5);Paul, S.(6);Berger, A.E.(6);Guirao, W.(7);Barrau, M.(7);Bastide, L.(7);Roblin, X.(7);Pflimlin-Fritschy, V.(8);Rutscher, U.(9);Hrúz, P.(8);Gerhold, C.B.(10);
(1)BÜHLMANN Laboratories AG, POC & ST Development, Schönenbuch, Switzerland;(2)BÜHLMANN Laboratories AG, POC & ST Marketing, Schönenbuch, Switzerland;(3)BÜHLMANN Laboratories AG, Regulatory Affairs, Schönenbuch, Switzerland;(4)BÜHLMANN Laboratories AG, Validation, Schönenbuch, Switzerland;(5)Kantonsspital Baselland, Gastroenterology and Hepatology, Liestal, Switzerland;(6)University Hospital of Saint-Etienne, Immunology laboratory- iBiothera reference center- CIC1408, Saint-Etienne, France;(7)Centre Hospitalier Universitaire de Saint-Étienne, Gastro-entérologie et Hépatologie maladies inflammatoires, Saint-Etienne, France;(8)Clarunis, Gastroenterology/Hepatology, Basel, Switzerland;(9)Claunis, Gastroenterology/Hepatology, Basel, Switzerland;(10)BÜHLMANN Laboratories AG, Development, Schönenbuch, Switzerland;
P438: Histological scores are poor predictors of short-term response to therapy in acute severe ulcerative colitisECCO'24Year: 2024
Authors: Jena, A.(1)*;Mishra, S.(1);Sekar, A.(2);Prasad, K.K.(1);Sachan, A.(1);Singh, A.K.(1);Shah, J.(1);Mandavdhare, H.S.(1);Singh, H.(3);Dutta, U.(1);Sharma, V.(1);
(1)Post Graduate Institute of Medical Education and Research, Gastroenterology, Chandigarh, India;(2)Post Graduate Institute of Medical Education and Research, Histopathology, Chandigarh, India;(3)Post Graduate Institute of Medical Education and Research, Surgical Gastroenterology, Chandigarh, India;
P439: Mild Crohn’s disease is characterized by a unique serum metabolomic signatureECCO'24Year: 2024
Authors: Bourgonje, A.R.(1)*;Ibing, S.(2,3);Argmann, C.(4);Sands, B.E.(1);Dubinsky, M.(1);Jacobsen, H.A.(5);Larsen, L.(5);Jess, T.(5);Suarez-Farinas, M.(6);Mehandru, S.(1);Colombel, J.F.(1);Ungaro, R.C.(1);
(1)Icahn School of Medicine at Mount Sinai, The Henry D. Janowitz Division of Gastroenterology- Department of Medicine, New York, United States;(2)Icahn School of Medicine at Mount Sinai, Hasso Plattner Institute for Digital Health at Mount Sinai, New York, United States;(3)University of Potsdam, Hasso Plattner Institute- Digital Engineering Faculty, Potsdam, Germany;(4)Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences, New York, United States;(5)Aalborg University, Center for Molecular Prediction of Inflammatory Bowel Disease- PREDICT- Department of Clinical Medicine- The Faculty of Medicine, Aalborg, Denmark;(6)Icahn School of Medicine at Mount Sinai, Center of Biostatistics, New York, United States;
P440: Myenteric plexitis and active inflammation at surgical margins are high-risk predictors for postoperative clinical recurrence of Crohn’s diseaseECCO'24Year: 2024
Authors: Okano, S.(1,2)*;Abe, K.(3);Sonoda, A.(1);Iwamoto, S.(1);Sako, M.(1);Okamoto, K.(4);Yamana, T.(4);Fukata, M.(1);
(1)Tokyo Yamate Medical Centre- Japan Community Healthcare Organization, Centre for Inflammatory Bowel disease- Division of Gastroenterology- Department of Internal Medicine, Tokyo, Japan;(2)Juntendo University- Graduate School of Medicine, Department of Human Pathology, Tokyo, Japan;(3)Tokyo Yamate Medical Centre- Japan Community Healthcare Organization, Department of Pathology, Tokyo, Japan;(4)Tokyo Yamate Medical Centre- Japan Community Healthcare Organization, Centre for Colorectal Surgery, Tokyo, Japan;
P441: Optimization of deep learning architectures for differentiating cytomegalovirus infection in severe ulcerative colitisECCO'24Year: 2024
Authors: Choe, A.R.(1)*;Jeong-Heon , K.(2);Ju Ran, B.(1);Yehyun , P.(1);Eun-Mi , S.(1);Rena , L.(3);Jin-Sung, K.(2);So-Hyun , A.(4);Sung-Ae , J.(1);
(1)Ewha Womans University College of Medicine, Department of Internal Medicine, Seoul, Korea- Republic Of;(2)Yonsei University College of Medicine, Department of medicine, seoul, Korea- Republic Of;(3)Ewha Womans University College of Medicine, Department of Bioengineering, seoul, Korea- Republic Of;(4)EwhaWomans University College of Medicine, Ewha Medical Research Institute, seoul, Korea- Republic Of;
P442: Renal lithogenic risk in patients with Inflammatory Bowel Diseases correlates with microbiota composition, urinary profile and dietary intake.ECCO'24Year: 2024
Authors: Mignini, I.(1);Blasi, V.(1)*;Masucci , L.(2);De Maio, F.(2);Agrillo, C.(2);Monzo , F.R.(2);Laterza, L.(1);Scaldaferri, F.(1);Napolitano, D.(1);Schiavoni, E.(1);D@E@ Amato , D.(3);De Ninno, G.(4);Baroni, S.(5);Mele, C.(6);Grassi, F.(6);Cintomi, M.(6);Garcovich, M.(1);Riccardi, L.(1);Gasbarrini, A.(1);Ferraro, P.M.(5);Papa, A.(1);
(1)Fondazione Policlinico Universitario A. Gemelli IRCCS, CEMAD - Centro Malattie dell’Apparato Digerente, Rome, Italy;(2)Fondazione Policlinico Universitario A. Gemelli IRCCS, Department of Laboratory and Infectious Sciences, Rome, Italy;(3)Università Cattolica del Sacro Cuore- Rome- Italy, UOC Chimica Biochimica e Biologia Molecolare Clinica, Rome, Italy;(4)Università Cattolica del Sacro Cuore, UOC Chimica Biochimica e Biologia Molecolare Clinica, Rome, Italy;(5)Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC Chimica Biochimica e Biologia Molecolare Clinica, Rome, Italy;(6)Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC Nutrizione clinica, Rome, Italy;
P443: Transmural Remission Associates with a Lower Risk of Phenotype Progression in Crohn’s DiseaseECCO'24Year: 2024
Authors: Fernandes, S.R.(1,2,3);Rodrigues, I.(4)*;Saraiva, S.(2,4);Bernardo, S.(2,4);Rita Gonçalves, A.(2,4);Moura Santos, P.(2,3,4);Valente, A.(4);Correia, L.(2,4,5);Cortez-Pinto, H.(4,5);Magro, F.(2,6,7,8,9);
(1)Hospital Santa Maria. Centro Hospitalar Universitário Lisboa Norte EPE, Serviço de Gastrenterologia e Hepatologia, Lisbon, Portugal;(2)Portuguese Group of Studies in Inflammatory Bowel Disease, Gedii, Porto, Portugal;(3)Faculdade de Medicina da Universidade de Lisboa, Clínica Universitária de Gastrenterologia, Lisbon, Portugal;(4)Centro Hospitalar Universitário Lisboa Norte EPE, Serviço de Gastrenterologia e Hepatologia, Lisbon, Portugal;(5)Faculdade de Medicina da Universidade de Lisboa, Clinica Universitária de Gastrenterologia, Lisbon, Portugal;(6)São João Hospital University Center, Gastroenterology Department, Porto, Portugal;(7)Faculty of Medicine- University of Porto, Department of Biomedicine- Unit of Pharmacology and Therapeutics- Porto- Portugal., Porto, Portugal;(8)Faculty of Medicine- University of Porto, Centre for Health Technology and Services Research- Health Research Network CINTESIS@RISE- Porto- Portugal, Porto, Portugal;(9)São João Hospital University Center, Clinical Pharmacology Unit, Porto, Portugal;
P444: Active perianal Crohn’s disease negatively impacts patients’ quality of life, psychosocial wellbeing and is associated with barriers related to social determinants of healthECCO'24Year: 2024
Authors: Shenoy, S.(1)*;Debroff, J.(2);Lacoste, J.(3);Giselbrecht, E.(3);Keefer, L.(3);Wong, S.Y.(3);
(1)Mount Sinai Morningside Hospital, Medicine, New York, United States;(2)Mount Sinai Beth Israel Hospital, Medicine, New York, United States;(3)Icahn School of Medicine at Mount Sinai, The Dr. Henry D. Janowitz Division of Gastroenterology, New York, United States;
P445: Wireless capsule endoscopy reading support for Crohn’s disease patients using deep neural networks with an active learning method.ECCO'24Year: 2024
Authors: Rouveyre, R.(1)*;Subileau-Langlois , T.(2);Gomez, T.(2);Mouchère , H.(2);Bourreille, A.(1);Leberre, C.(1);
(1)Institut des Maladies de l@E@Appareil Digestif- Nantes University Hospital, Loire Atlantique 44, Nantes, France;(2)Nantes University- LS2N, Loire Atlantique 44, Nantes, France;
P446: Influence of seasonal vitamin D deficit in clinical course of inflammatory bowel disease patientsECCO'24Year: 2024
Authors: Baz-Lopez, A.(1)*;Baston-Rey, I.(2);Martí-Marqués, E.(1);Calvino-Suarez, C.(2);Santos-Blanco, E.(1);Ferreiro-Iglesias, R.(2);Blanco-Hortas, A.(1);Lopez-Roses, L.(1);Dominguez-Munoz, J.E.(2);Barreiro-de Acosta, M.(2);
(1)Hospital Lucus Augusti, Department of Gastroenterology, Lugo, Spain;(2)University Hospital Santiago De Compostela CHUS, Department of Gastroenterology-IBD Unit, Santiago De Compostela, Spain;
P447: Anti-αvβ6 integrin antibody as a novel serum biomarker for diagnosis of ulcerative colitis; a nation-wide multicenter validation study in JapanECCO'24Year: 2024
Authors: Okabe, M.(1)*;Yamamoto, S.(1);Kitamoto, H.(1);Kuwada, T.(1);Shiokawa, M.(1);Yamazaki , H.(2);Seno, H.(1);
(1)Graduate School of Medicine- Kyoto university, Gastroenterology and Hepatology, Kyoto, Japan;(2)Graduate School of Medicine- Kyoto University, Community Medicine, Kyoto, Japan;UCV6 Dx Study Group
