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1University of Campinas, Department of Surgery, IBD Research Laboratory, Campinas, Brazil 2University of Campinas, Cell Signaling Laboratory, Department of Internal Medicine, Campinas, Brazil 3IDIBAPS, CIBERehd, Bioinformatics Platform, Barcelona, Spain

P025

Transcriptional and molecular pathways activated in mesenteric adipose tissue and intestinal mucosa of Crohn's disease patients

Year: 2017
Source:

1University of Campinas, Department of Surgery, IBD Research Laboratory, Campinas, Brazil 2University of Campinas, Cell Signaling Laboratory, Department of Internal Medicine, Campinas, Brazil 3IDIBAPS, CIBERehd, Bioinformatics Platform, Barcelona, Spain

Authors:

Coope A.1, Pascoal L.B.1, Silva F.A.R.1, Botezelli J.D.1, Ayrizono M.L.S.1, Milanski M.2, Camargo M.G.1, Planell N.3, Portovedo M.2, Dias C.B.1, Fagundes J.J.1, Leal R.F.*1

P026

Characterisation of mucosal CD4+ T-cells in peripheral blood of healthy controls and paediatric inflammatory bowel disease patients

Year: 2016
Authors:

M. Joosse*1, C. Menckeberg1, L. de Ruiter1, H. Raatgeep1, L. van Berkel1, F. Muskens2, R. Hendriks2, R. Hoogenboezem3, T. Cupedo3, L. de Ridder4, H. Escher4, S. Veenbergen1, J. Samsom1

1Erasmus MC, Laboratory of Paediatrics, division Gastroenterology and Nutrition, Rotterdam, Netherlands, 2Erasmus MC, Department of Pulmonary Medicine, Rotterdam, Netherlands, 3Erasmus MC, Department of Haematology, Rotterdam, Netherlands, 4Erasmus MC, Department of Paediatric Gastroenterology, Rotterdam, Netherlands

1University of Limerick, Graduate Entry Medical School and Centre for Interventions in Infection, Inflammation and Immunity (4i), Limerick, Ireland 2University Hospitals Limerick, Department of Surgery, Limerick, Ireland 3University Hospitals Limerick, Department of Gastroenterology, Limerick, Ireland 4University Hospitals Limerick, Department of Pathology, Limerick, Ireland

P026

The role of fibrocytes in mesenteric Crohn's disease

Year: 2017
Source:

1University of Limerick, Graduate Entry Medical School and Centre for Interventions in Infection, Inflammation and Immunity (4i), Limerick, Ireland 2University Hospitals Limerick, Department of Surgery, Limerick, Ireland 3University Hospitals Limerick, Department of Gastroenterology, Limerick, Ireland 4University Hospitals Limerick, Department of Pathology, Limerick, Ireland

Authors:

Kiernan M.G.*1, Sahebally S.M.1,2, Kiely P.A.1, Waldron D.2, Moloney M.3, Skelly M.3, Faul P.N.4, O'Leary D.P.2, Lowery A.J.1,2, Walsh L.G.1,2, Dunne C.P.1, Coffey J.C.1,2

P027

Characterisation of human intestinal dendritic cells and macrophages through the lower gastrointestinal tract.

Year: 2016
Authors:

D. Bernardo*, A. C. Marín, P. M. Linares, M. Jiménez, M. Chaparro, J. P. Gisbert

Hospital Universitario de La Princesa, IIS-IP and CIBERehd, Gastroenterology Unit, Madrid, Spain

1University of Glasgow, Infection, Immunity and Inflammation, Glasgow, United Kingdom 2University of Manchester, Manchester, United Kingdom 3Glasgow Royal Infirmary, Glasgow, United Kingdom

P027

Comparing the immunological signatures of inflammatory diseases

Year: 2017
Source:

1University of Glasgow, Infection, Immunity and Inflammation, Glasgow, United Kingdom 2University of Manchester, Manchester, United Kingdom 3Glasgow Royal Infirmary, Glasgow, United Kingdom

Authors:

McDonald E.*1, Wright P.1, Zangerle-Murray T.2, Jung J.1, Gaya D.3, Siebert S.1, McInnes I.1, Milling S.1

P028

Inflammatory bowel disease is associated with cytoskeleton rearrangement in the epithelial cells

Year: 2016
Authors:

A. Portyanko1, P. Perevoschikov1, K. Ruksha1, J. Gorgun*2

1Belarusian State Medical University, Department of Pathology, Minsk, Belarus, 2Belarusian Medical Academy of Postgraduate Education, Department of Gastroenterology and Nutrition, Minsk, Belarus

1Asan Medical Center, Gastroenterology, Seoul, South Korea 2Cha Bundang Medical Center, Cha University, Department of Gastroenterology, Seongnam-Si, South Korea

P028

Oligonol attenuates dextran sulfate sodium-induced colitis and reduces flare-UP in mice by enhancing host defense mechanism

Year: 2017
Source:

1Asan Medical Center, Gastroenterology, Seoul, South Korea 2Cha Bundang Medical Center, Cha University, Department of Gastroenterology, Seongnam-Si, South Korea

Authors:

Kim K.-J.*1, Park J.-M.2, Han Y.-M.2, Lee S.G.2, Shin S.A.2, Hahm K.-B.2

Hacettepe University, Gastroenterology, Ankara, Turkey

P029

Azelnidipine, a novel calcium channel blocker, ameliorates severity of colitis in DSS induced colitis in mice possibly by modulating tissue levels of TNF-alpha and IL-6

Year: 2017
Source:

Hacettepe University, Gastroenterology, Ankara, Turkey

Authors:

Kav T., Akyol A., Aksoy E., Ozer C., Torgutalp M., Sivri B.

P029

Intestinal mesenchymal-specific IKK2 promotes initiation of colitis and colitis-associated cancer

Year: 2016
Authors:

V. Koliaraki*1, M. Pasparakis2, G. Kollias1, 3

1BSRC "Alexander Fleming", Vari, Greece, 2University of Cologne, Institute of Genetics, Cologne, Germany, 3University of Athens, Department of Physiology, Athens, Greece

P030

Development of small bowel tissue phantom for microultrasound 
investigation

Year: 2016
Authors:

T. Anbarasan*1, C. E. M. Démoré1, H. Lay2, M. R. S. Sunoqrot1, R. Poltarjonoks1, S. Cochran2, B. F. Cox1

1University of Dundee, Dundee, United Kingdom, 2University of Glasgow, Glasgow, United Kingdom

1Yeungnam University, College of Pharmacy, Gyeongsan, South Korea 2Hanyang University, College of Pharmacy, Ansan, South Korea

P030

Inhibitory activity of 6-amino-2,4,5-trimethylpyridin-3-ols against inflammatory cell adhesion and recruitment to colon epithelium

Year: 2017
Source:

1Yeungnam University, College of Pharmacy, Gyeongsan, South Korea 2Hanyang University, College of Pharmacy, Ansan, South Korea

Authors:

Jeong B.-S.*1, Banskota S.1, Kang H.-e.2, Kim J.-A.1, Nam T.-g.2

1Universiti Kebangsaan Malaysia, Medicine, Kuala Lumpur, Malaysia 2Universiti Sains Islam Malaysia, Medicine, Kuala Lumpur, Malaysia 3Universiti Teknologi MARA, Medicine, Kuala Lumpur, Malaysia

P031

Identification of alternative splicing in transcript isoforms in patients with ulcerative colitis: effects of disease duration

Year: 2017
Source:

1Universiti Kebangsaan Malaysia, Medicine, Kuala Lumpur, Malaysia 2Universiti Sains Islam Malaysia, Medicine, Kuala Lumpur, Malaysia 3Universiti Teknologi MARA, Medicine, Kuala Lumpur, Malaysia

Authors:

Low E.N.D.*1, Wong Z.1, Ngiu C.S.1, Nazefah A.H.2, Rafiz A.R.3, Mokhtar N.1, Raja Ali R.A.1

P031

STAT6 deficiency alters macrophage polarisation and promotes fibrosis in a murine model of chronic inflammation

Year: 2016
Authors:

P. Salvador*1, D. Ortiz-Masiá1, D. C. Macias-Ceja1, 2, J. Cosín-Roger1, L. Gisbert-Ferrándiz1, C. Hernández2, S. Calatayud1, M. D. Barrachina-Sancho1

1University of Valencia, Valencia, Spain, 2Fisabio Hospital Peset, Valencia, Spain

P032

IFN-γ controls the immunomodulatory properties of bone marrow mesenchymal stem cells via a microRNA29a/STAT-3 dependent mechanism

Year: 2016
Authors:

A. Oikonomopoulos*1, P. Lacey1, T. Tomakili1, D. Iliopoulos2, 
D. W. Hommes1

1UCLA Centre for Inflammatory Bowel Diseases, Division of Digestive Diseases, Los Angeles, California, United States, 2UCLA Centre for Systems Biomedicine, Division of Digestive Diseases, Los Angeles, California, United States

1Topivert Pharma Ltd, London, United Kingdom 2University of East Anglia, Norwich Medical School, Norwich, United Kingdom 3Barts and London School of Medicine and Dentistry, Centre of Immunobiology, London, United Kingdom

P032

The pharmacological profile of TOP1288, a narrow spectrum kinase inhibitor in clinical development as an anti-inflammatory treatment for ulcerative colitis

Year: 2017
Source:

1Topivert Pharma Ltd, London, United Kingdom 2University of East Anglia, Norwich Medical School, Norwich, United Kingdom 3Barts and London School of Medicine and Dentistry, Centre of Immunobiology, London, United Kingdom

Authors:

Foster M.*1, Biancheri P.2, Fyfe M.1, MacDonald T.3, Rowley A.1, Sirohi S.1, Solanke Y.1, Webber S.1, Walshe C.1

P033

Anti-TNF-α therapy normalises aberrant cytokine production and homing profile of circulating dendritic cells in Crohn’s disease

Year: 2016
Authors:

P. Hendy*1, 2, D. Reddi2, D. Bernardo3, L. Durant2, A. Noble2, N. English2, S. Knight2, A. Hart1

1St Mark’s Hospital, Gastroenterology, LONDON, United Kingdom, 2Imperial College, Antigen Presentation Research Group, London, United Kingdom, 3Hospital Universitario de La Princesa, Department of Immunology, Madrid, Spain

1Universitat Autònoma de Barcelona, Cell Biology, Physiology and Immumology, Bellaterra, Spain 2Esteve, Department of Pharmacology, Drug Discovery & Preclinical Development, Barcelona, Spain

P033

DSS-induced colitis is attenuated in sigma-1 receptor knockout mice

Year: 2017
Source:

1Universitat Autònoma de Barcelona, Cell Biology, Physiology and Immumology, Bellaterra, Spain 2Esteve, Department of Pharmacology, Drug Discovery & Preclinical Development, Barcelona, Spain

Authors:

Lόpez-Estévez S.*1, Aguilera M.1, Gris G.2, de la Puente B.2, Codony X.2, Zamanillo D.2, Martínez V.1

Universitat Autònoma de Barcelona, Cell Biology, Physiology and Immumology, Bellaterra, Spain

P034

Altered microbiota and host-bacterial interactions during the spontaneous development of colitis in IL-10 knockout mice

Year: 2017
Source:

Universitat Autònoma de Barcelona, Cell Biology, Physiology and Immumology, Bellaterra, Spain

Authors:

Lόpez-Estévez S., Aguilera M., Martínez V.

P034

Immunoregulatory properties of human adipose–derived stem cells in inflammatory diseases: differences between Crohn´s disease and obesity

Year: 2016
Authors:

C. Serena*1, 2, N. Keiran2, M. Millan2, M. Ejarque1, 2, R. Fradera3, E. Espin4, K. Roche1, 2, J. Vendrell1, 2, S. Fernandez-Veledo1, 2

1Health Institute Pere Virgili, Research Unit, Tarragona, Spain, 2Hospital Joan XXIII, Tarragona, Spain, 3Hospital St. Pau i Sta Tecla, Tarragona, Spain, 4Hospital Vall d’Hebron, Barcelona, Spain

P035

Lamina propria CD4+LAP+ Foxp3- regulatory cells are involved in limiting the disease extension in Ulcerative Colitis

Year: 2016
Authors:

A. Butera1, A. Amendola1, M. Sanchez2, S. Piroli3, A. Pronio3, D. De Nitto4, R. Pica4, M. Boirivant*1

1Istituto Superiore di Sanità, Dept Infectious, Parasitic and Immune-mediated Diseases, Roma, Italy, 2Istituto Superiore di Sanità, Dept Cell Biology and Neurosciences, Rome, Italy, 3University ‘Sapienza’, Dept General Surgery, ‘P. Stefanini’, Roma, Italy, 4Sandro Pertini Hospital, IBD, GE Unit, Roma, Italy

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