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1Universidad de Valencia-CIBERehd, Department of Pharmacology, Valencia, Spain 2Universidad de Valencia, Department of Medicine, Valencia, Spain 3Universidad de Valencia, Department of Pharmacology, Valencia, Spain 4FISABIO Hospital Peset, Department of Pharmacology, Valencia, Spain

P015

Wnt10b promotes fibrosis in murine colitis

Year: 2017
Source:

1Universidad de Valencia-CIBERehd, Department of Pharmacology, Valencia, Spain 2Universidad de Valencia, Department of Medicine, Valencia, Spain 3Universidad de Valencia, Department of Pharmacology, Valencia, Spain 4FISABIO Hospital Peset, Department of Pharmacology, Valencia, Spain

Authors:

Ortiz-Masia D.*1,2, Salvador P.3, Macias-Ceja D.C.4, Gisbert-Ferrándiz L.3, Hernandez C.4, Calatayud S.3, Esplugues J.V.3,4, Barrachina D.3

P016

Guggulsterone ameliorates colitis by suppressing TREM-1 hyperactivation and modulating macrophage phenotypes

Year: 2016
Authors:

X. Che*1, 2, K. C. Park3, S. J. Park1, 4, Y. H. Kang1, H. A. Jin1, 2, D. H. Seo1, 2, S. W. Kim1, 2, 4, T. I. Kim1, W. H. Kim1, J. H. Cheon1, 2, 4

1Yonsei University, Internal Medicine and Institute of Gastroenterology, Seoul, South Korea, 2Yonsei University, Brain Korea 21 PLUS Project for Medical Science, Seoul, South Korea, 3Yonsei University, Seoul, South Korea, 4Severance Biomedical Science Institute, Seoul, South Korea

Erasmus Medical Center, Gastroenterology and Hepatology, Rotterdam, Netherlands

P016

Pregnancy in IBD: direct effect of sex-hormones on epithelial barrier function

Year: 2017
Source:

Erasmus Medical Center, Gastroenterology and Hepatology, Rotterdam, Netherlands

Authors:

van der Giessen J., van der Woude C., Peppelenbosch M., Fuhler G.

1University Hospital Zurich, University of Zurich, Gastroenterology and Hepatology, Zurich, Switzerland 2University Hospital Zurich, Clinic of Visceral and Transplantation Surgery, Zurich, Switzerland 3Novartis Institutes for Biomedical Research, Basel, Switzerland

P017

OGR1 (GPR68) expression is increased in intestinal inflammation and correlates with disease activity in patients with IBD

Year: 2017
Source:

1University Hospital Zurich, University of Zurich, Gastroenterology and Hepatology, Zurich, Switzerland 2University Hospital Zurich, Clinic of Visceral and Transplantation Surgery, Zurich, Switzerland 3Novartis Institutes for Biomedical Research, Basel, Switzerland

Authors:

Cosin-Roger J.1, Bengs S.1, Lang S.1, Turina M.2, Rickenbacher A.2, Seuwen K.3, Ruiz P.A.1, Misselwitz B.1, Rogler G.1, de Vallière C.*1

P017

Periostin aggravates the development of colitis-associated colon cancer in mice

Year: 2016
Authors:

S.-J. Koh*1, J. W. Kim1, B. G. Kim1, K. L. Lee1, J. S. Kim2

1Seoul National University Boramae Hospital, Seoul National University College of Medicine, Internal Medicine, Seoul, South Korea, 2Seoul National University College of Medicine, Internal Medicine and Liver Research Institute, Seoul, South Korea

P018

Biologic functions between non-affected and affected margins of ileum samples from Crohn’s disease patients who will develop post-surgical recurrence.

Year: 2016
Authors:

V. Loren*1, 2, A. Garcia-Jaraquemada1, A. Aterido3, F. Kamberovic1, A. Julià3, Y. Zabana4, A. Alonso3, M. Mañosa2, 5, S. Marsal3, E. Domènech2, 5, E. Cabré2, 5, J. Manyé2, 6

1Health Sciences Research Institute of the ‘Germans Trias i Pujol’ Foundation (IGTP), Inflammatory Bowel Disease Unit, Badalona, Spain, 2Centro de Investigación Biomédica en Red (CIBER), Madrid, Spain, 3Institute for research in Biomedicine, Rheumatology Research Group, Barcelona, Spain, 4Mútua de Terrassa Hospital, Terrassa, Spain, 5Germans Trias i Pujol Hospital, Inflammatory Bowel Disease Unit, Badalona, Spain, 6Health Sciences Research Institute of the ‘Germans Trias i Pujol’ Foundation (IGTP), Inflammatory Bowel Disease Unit, Badalona, Spain

1St Vincent's Hospital, Inflammatory Bowel Disease, Melbourne, Australia 2St Mark's Hospital, Inflammatory Bowel Disease Unit, London, United Kingdom 3Imperial College London, Department of Surgery and Cancer, London, United Kingdom 4St Mark's Hospital, IBD, London, United Kingdom 5Imperial College, Surgery and Cancer, London, United Kingdom

P018

Complete metabonomic and microbiota profiling identifies biomarkers for anti-TNF therapy response

Year: 2017
Source:

1St Vincent's Hospital, Inflammatory Bowel Disease, Melbourne, Australia 2St Mark's Hospital, Inflammatory Bowel Disease Unit, London, United Kingdom 3Imperial College London, Department of Surgery and Cancer, London, United Kingdom 4St Mark's Hospital, IBD, London, United Kingdom 5Imperial College, Surgery and Cancer, London, United Kingdom

Authors:

Ding N.S.*1,2,3, Sarafian M.3,4, Perdones-Montero A.5, Misra R.4, Hendy P.4, Penez L.4, Holmes E.3, Hart A.3,4

1Fondazione Policlinico Universitario Gemelli, Catholic University of Sacred Heart, Gastroenterological Area, Gastroenterological and Endocrino-Metabolical Sciences Department, ROME, Italy 2Catholic University of Sacread Hearth, “A. Gemelli” Hospital, Department of Microbiology, Rome, Italy 3Catholic University of Sacred Heart of Rome, Department of Pathology, Rome, Italy

P019

Anti-TNF-alpha therapy induces microbial and immunological changes in dextran sodium sulphate chronic colitis

Year: 2017
Source:

1Fondazione Policlinico Universitario Gemelli, Catholic University of Sacred Heart, Gastroenterological Area, Gastroenterological and Endocrino-Metabolical Sciences Department, ROME, Italy 2Catholic University of Sacread Hearth, “A. Gemelli” Hospital, Department of Microbiology, Rome, Italy 3Catholic University of Sacred Heart of Rome, Department of Pathology, Rome, Italy

Authors:

Petito V.*1, Graziani C.1, Lopetuso L.1, Quaranta G.2, Paroni Sterbini F.2, Masucci L.2, Sgambato A.3, Cammarota G.1, Sanguinetti M.2, Gasbarrini A.1, Scaldaferri F.1

P019

Informing ulcerative colitis pathophysiology and outcomes through metabolic pofiling

Year: 2016
Authors:

S. Fong*1, C. Le Roy2, J. Sanderson1, S. Claus2

1Guy’s and St Thomas’ NHS Foundation Trust, IBD Centre, London, United Kingdom, 2University of Reading, Department of Food and Nutritional Sciences, Reading, United Kingdom

P020

The efficacy of tofacitinib and a selective Janus kinase 1 inhibitor in dextran sulphate sodium colitis models

Year: 2016
Authors:

L. De Vries*1, 2, F. van Leeuwen-Hilbers2, P. van Hamersveld2, V. Ludbrook3, G. D’Haens1, W. De Jonge2

1Academic Medical Centre (AMC), Gastroenterology & Hepatology, Amsterdam, Netherlands, 2Academic Medical Centre (AMC), Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands, 3GlaxoSmithKline, Immuno-Inflammation Therapy Area, Stevenage, United Kingdom

1IDIBAPS, Experimental Gastroenterology, Barcelona, Spain 2CIBERehd, Barcelona, Spain 3Academic Medical Center (AMC), Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands 4Hospital Clinic de Barcelona, Department of Pathology, Barcelona, Spain 5Hospital Clinic de Barcelona, Department of Gastroenterology, Barcelona, Spain

P020

Wnt5b could contribute to regeneration of the epithelium in inflammatory bowel disease by potentiating epithelial mesenchymal transition

Year: 2017
Source:

1IDIBAPS, Experimental Gastroenterology, Barcelona, Spain 2CIBERehd, Barcelona, Spain 3Academic Medical Center (AMC), Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands 4Hospital Clinic de Barcelona, Department of Pathology, Barcelona, Spain 5Hospital Clinic de Barcelona, Department of Gastroenterology, Barcelona, Spain

Authors:

Dotti I.*1, Ferrer-Picόn E.1, Planell N.1,2, van Herk E.H.3, Cuatrecasas M.4, Panés J.5, Salas A.1

P021

Inflammatory monocytes are key regulators of colonic inflammation in murine and human IBD

Year: 2016
Authors:

G.-R. Jones*1, P. Cook2, A. MacDonald2, T. Fenton2, A. Kelly2, M. Travis2, S. Campbell3

1University of Edinburgh, Gastroenterology, Edinburgh, United Kingdom, 2University of Manchester, Department of Immunology, Manchester, United Kingdom, 3University of Manchester / Manchester Royal Infirmary, Department of Gastroenterology, Jean Mcfarlane Building; School for Nursing, Manchester, United Kingdom

1Dr. Josep Trueta University Hospital, Institute of biomedical investigation of Girona, Girona, Spain 2Vic University Hospital, Gastroenterology, Vic, Spain 3Dr. Josep Trueta University Hospital, Gastroenterology, Girona, Spain

P021

Utility of therapeutic anti-TNF drug monitoring in hospitals with different degree of experience in the treatment of inflammatory bowel disease

Year: 2017
Source:

1Dr. Josep Trueta University Hospital, Institute of biomedical investigation of Girona, Girona, Spain 2Vic University Hospital, Gastroenterology, Vic, Spain 3Dr. Josep Trueta University Hospital, Gastroenterology, Girona, Spain

Authors:

Vila M.*1, Bahi A.1, Miquel J.O.2, Busquets D.3, Salό J.2, Aldeguer X.3

KU Leuven, P.O. Box 701, Department of Clinical and Experimental Medicine, Leuven, Belgium

P022

MET deletion in MRP8+ neutrophils is protective during DDS-induced colitis via Th17 pathway

Year: 2017
Source:

KU Leuven, P.O. Box 701, Department of Clinical and Experimental Medicine, Leuven, Belgium

Authors:

Stakenborg M., Meroni E., Goverse G., Matteoli G.

P022

Parthenolide enhances the efficacy of anti-tumour effect of balsalazide in human colon cancer cells and colitis-associated colorectal cancer by blockade of NF-kB activation

Year: 2016
Authors:

G. S. Seo1, S.-L. Kim2, S. W. Kim*2

1Wonkwang university college of medicine, Internal medicine, Iksan, South Korea, 2Chonbuk national university hospital, Internal medicine, Jeonju, South Korea

P023

Development of methods to investigate effects of narrow spectrum kinase inhibitors on cellular phosphorylation of kinase substrates

Year: 2016
Authors:

S. Sirohi*, M. Foster, M. Fyfe, Y. Solanke, S. Webber, C. Walshe

Topivert Pharma, London, United Kingdom

1Massachusetts General Hospital, Department of Gastroenterology, Boston, United States 2University of Groningen, Groningen, Netherlands 3Massachusetts General Hospital, Boston, United States 4Harvard Medical School, Boston, United States

P023

Fatigue in quiescent inflammatory bowel disease is associated with low GM-CSF levels and metabolomic alterations

Year: 2017
Source:

1Massachusetts General Hospital, Department of Gastroenterology, Boston, United States 2University of Groningen, Groningen, Netherlands 3Massachusetts General Hospital, Boston, United States 4Harvard Medical School, Boston, United States

Authors:

Borren N.*1,2, Goel G.3,4, Lassen K.1, Devaney K.1, Cleland T.1, Garber J.1,4, Khalili H.1,4, Yajnik V.1,4, Xavier R.1,4, Ananthakrishnan A.1,4

1Istituto Superiore di Sanità, Dept Infectious, Parasitic and Immune-mediated Diseases, Roma, Italy 2Sandro Pertini Hospital, IBD, GE Unit, Roma, Italy 3University “Sapienza”, Dept General Surgery, “P. Stefanini”, Rome, Italy 4Istituto Superiore di Sanità, Dept Environment and Health, Rome, Italy 5University “Sapienza”, Dept. General Surgery, “P. Stefanini”, Roma, Italy

P024

Stratification of ulcerative colitis patients according to distinctive tissue cytokine profiles

Year: 2017
Source:

1Istituto Superiore di Sanità, Dept Infectious, Parasitic and Immune-mediated Diseases, Roma, Italy 2Sandro Pertini Hospital, IBD, GE Unit, Roma, Italy 3University “Sapienza”, Dept General Surgery, “P. Stefanini”, Rome, Italy 4Istituto Superiore di Sanità, Dept Environment and Health, Rome, Italy 5University “Sapienza”, Dept. General Surgery, “P. Stefanini”, Roma, Italy

Authors:

Butera A.*1, De Nitto D.2, Ciamberlano B.3, Giuliani A.4, Pica R.2, Pronio A.5, Boirivant M.1

P024

Therapeutic potential of the human amniotic fluid mesenchymal stem cells/stroma cells secreted molecules in a mice model of colitis

Year: 2016
Authors:

M. Gazouli*1, E. Legaki1, M. Roubelakis1, A. Lazaris2, G. Karamanolis3, E. Marinos1, G. Theodoropoulos4

1School of Medicine, University of Athens, Biology, Athens, Greece, 2School of Medicine, University of Athens, Pathology, Athens, Greece, 3School of Medicine, University of Athens, Gastroenterology, Athens, Greece, 4School of Medicine, University of Athens, Surgery, Athens, Greece

P025

Tonsil-derived mesenchymal stem cell ameliorate intestinal fibrosis in chronic murine colitis model

Year: 2016
Authors:

E. M. Song*1, S.-A. Jung1, S.-E. Kim1, K. E. Lee1, J. Y. Chang1, H. M. Son1, M. S. Ryu1, Y. H. Joo1, C. H. Tae1, C. M. Moon1, H.-K. Jung1, K.-N. Shim1, I. H. Jo2, Y. S. Yu2

1Ewha Woman’s University School of Medicine, Department of Internal Medicine, Ewha Medical Research Institute, Seoul, South Korea, 2Ewha Woman’ University School of Medicine, Department of Molecular Medicine, Ewha Medical Research Institute, Seoul, South Korea

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