¹Tor Vergata University, Department of Surgery, Rome, Italy, ²Tor Vergata University, Surgery, Rome, Italy

Coimbra Hospital and University Center, Gastroenterology, Coimbra, Portugal

The Second Affiliated Hospital of Soochow University, Gastroenterology, Suzhou, China

¹Scripps Clinic, Division of Gastroenterology, La Jolla, USA, ²The Scripps Research Institute, Scripps Translational Science Institute, La Jolla, USA, ³The Scripps Research Institute, Department of Integrative Structural and Computational Biology, La Jolla, USA, ⁴University of California, San Diego, Division of Gastroenterology, La Jolla, USA, ⁵University of Pennsylvania, Center for Clinical Epidemiology and Biostatistics, Philadelphia, USA, ⁶Scripps Clinic, Department of Internal Medicine, La Jolla, USA, ⁷San Diego State University, School of Exercise and Nutritional Sciences, San Diego, USA

¹ASST Fatebenefratelli Sacco, DIBIC “L. Sacco” University of Milan, Gastrointestinal Unit, Milan, Italy, ²University Hospital of Parma, Department of Gastroenterology and Digestive Endoscopy, Parma, Italy

¹Kyorin University School of Medicine, Third Department of Internal Medicine, Tokyo, Japan, ²Iwate Medical University School of Medicine, Division of Gastroenterology, Department of Medicine, Morioka, Japan, ³Hyogo College of Medicine, Department of Intestinal Inflammation Research, Nishinomiya, Japan, ⁴Sapporo Medical University School of Medicine, Department of Gastroenterology and Hepatology, Sapporo, Japan, ⁵Sapporo Kosei General Hospital, Inflammatory Bowel Disease Center, Sapporo, Japan, ⁶Tokyo Yamate Medical Center, Department of Medicine, Division of Gastroenterology, Tokyo, Japan, ⁷Ishida Clinic of IBD and Gastroenterology, Oita, Japan, ⁸Saitama Medical Center, Saitama Medical University, Department of Gastroenterology and Hepatology, Saitama, Japan, ⁹Graduate School of Medicine, Chiba University, Department of Gastroenterology and Nephrology, Chiba, Japan, ¹⁰Graduate School of Medical Sciences, Kyushu University, Department of Medicine and Clinical Science, Fukuoka, Japan, ¹¹Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Tokyo, Japan, ¹²Fukuoka University Chikushi Hospital, Department of Gastroenterology, Chikushino, Japan, ¹³Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Department of Molecular Gastroenterology and Hepatology, Kyoto, Japan, ¹⁴Keio University School of Medicine, Department of Internal Medicine, Tokyo, Japan, ¹⁵Toho University Sakura Medical Center, Department of Internal Medicine, Sakura, Japan, ¹⁶The Institute of Medical Science Hospital, The University of Tokyo, Center for Translational Research, Tokyo, Japan, ¹⁷Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Tokyo, Japan, ¹⁸Kitasato University Kitasato Institute Hospital, Center for Advanced IBD Research and Treatment, Tokyo, Japan

¹Austin Health, Department of Gastroenterology, Melbourne, Australia, ²University of Melbourne, Austin Academic Centre, Melbourne, Australia, ³St Vincent's Hospital, Department of Gastroenterology, Melbourne, Australia, ⁴Mount Sinai, Icahn School of Medicine, New York, USA, ⁵McGill University Health Centre, Division of Gastroenterology, Montreal, Canada, ⁶Royal Brisbane and Women's Hospital, Department of Gastroenterology and Hepatology, Brisbane, Australia, ⁷Leeds Teaching Hospitals NHS Trust, Gastroenterology Institute, Leeds, UK, ⁸University of Leeds, Leeds Institute of Biomedical and Clinical Sciences, Leeds, UK

¹University of Manitoba, Pediatrics, Winnipeg, Canada, ²Hospital for Sick Children, University of Toronto, Department of Paediatrics; Department of Gastroenterology, Hepatology and Nutrition, Toronto, Canada, ³University of Alberta, Department of Pediatrics, Edmonton, Canada, ⁴Pediatrics, University of Calgary, Calgary, Canada, ⁵University of Ottawa, Department of Pediatrics, Ottawa, Canada, ⁶BC Children's Hospital, Vancouver, Canada, ⁷McMaster University, Department of Pediatrics, Hamilton, Canada

¹Robarts Clinical Trials, Western University, Ontario, Canada, ²University of California - San Diego, San Diego, USA, ³Academic Medical Center, Amsterdam, The Netherlands, ⁴Mayo Clinic, Department of Laboratory Medicine and Pathology, Scottsdale, USA, ⁵Northwestern University Feinberg School of Medicine, Chicago, USA, ⁶Atlanta Gastroenterology Associates, Atlanta, USA, ⁷University of Leuven, Leuven, Belgium, ⁸University of Calgary, Calgary, Canada, ⁹Receptos, a Wholly Owned Subsidiary of Celgene, San Diego, USA

¹Faculdade Farmacia Universidade Lisboa, iMed - Research Institute for Medicines, Lisboa, Portugal, ²iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal, ³Bayer Portugal, Carnaxide, Portugal, ⁴Centro Interdisciplinar de Investigação em Sanidade Animal (CIISA), Faculdade de Medicina Veterinária, University of Lisbon, Lisboa, Portugal, ⁵Hospital Garcia de Orta (HGO), Almada, Portugal, ⁶Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal, ⁷CEDOC/NOVA Medical School, Lisbon, Portugal, ⁸Immunomediated Systemic Diseases Unit (UDIMS), Fernando Fonseca Hospital, Amadora, Portugal, ⁹Galway University Hospitals, Department of Rheumatology, Galway, Ireland, ¹⁰Charite Universitaetsmedizin Berlin, Department Medicine Rheumatology and Clinical Immunology, Berlin, Germany, ¹¹Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Rheumatology Department, Lisboa, Portugal, ¹²Hospital Beatriz Ângelo, Division of Gastroenterology, Loures, Portugal, ¹³Unidade de Gastroenterologia of CHBM, Barreiro, Portugal, ¹⁴Humanitas University; Humanitas Clinical and Research Centre, Department of Biomedical Sciences, Milan, Italy, ¹⁵Academic Medical Center, Amsterdam, The Netherlands, ¹⁶Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Department of Gastroenterology, Tel-Aviv, Israel, ¹⁷Portuguese Institute of Oncology of Lisbon Francisco Gentil, EPE, Lisboa, Portugal, ¹⁸Hospital de Santa Maria, Department of Gastroenterology and Hepatology, Lisboa, Portugal, ¹⁹Faculty of Medicine, University of Porto, Centro Hospitalar São João, Gastroenterology Department, Porto, Portugal, ²⁰Semmelweis University, First Department of Medicine, Budapest, Hungary, ²¹McGill University, MUHC, Montreal General Hospital, Division of Gastroenterology, Montreal, Canada

¹St. Paul's Hospital, Vancouver, Canada, ²Evidera, St-Laurent, Canada, ³Evidera, London, UK, ⁴Takeda, Oakville, Canada, ⁵Takeda Development Centre Europe Ltd., London, UK

¹Faculty of Medicine and Health, Örebro University, Department of Gastroenterology, Örebro, Sweden, ²Linköping University, Department of Gastroenterology, Linköping, Sweden, ³Danderyd Hospital, Department of Internal Medicine, Stockholm, Sweden, ⁴Skåne University Hospital, Department of Gastroenterology, Malmö, Sweden, ⁵St Göran Hospital, Department of Internal Medicine, Stockholm, Sweden, ⁶Karolinska Institute, Department of Medicine, Stockholm, Sweden, ⁷Skåne University Hospital, Department of Gastroenterology, Lund, Sweden, ⁸Kungsbacka Hospital, Department of Internal Medicine, Kungsbacka, Sweden, ⁹Takeda Pharma AB, Solna, Sweden, ¹⁰Ersta Hospital, Department of Gastroenterology, Stockholm, Sweden, ¹¹Södra Älvsborgs Hospital, Department of Internal Medicine, Borås, Sweden, ¹²Skaraborgs Hospital, Department of Internal Medicine, Lidköping, Sweden, ¹³Sunderby Hospital, Department of Internal Medicine, Sunderbyn, Sweden, ¹⁴Örebro University, Clinical Epidemiology and Biostatistics, Örebro, Sweden

University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium

¹Division of Internal Medicine, “Villa Sofia-Cervello” Hospital, Palermo, Italy, ²Unit of Surgery, “Villa Sofia-Cervello” Hospital, Palermo, Italy, ³Unit of Pathology, Villa Sofia-Cervello'' Hospital, Palermo, Italy, ⁴Radiology Unit, “Villa Sofia-Cervello” Hospital, Palermo, Italy

¹University of Calgary, Gastroenterology, Calgary, Canada, ²University of Calgary, Community Health Sciences, Calgary, Canada, ³University of Calgary, Foothills Medical Centre, Diagnostic Imaging, Calgary, Canada

¹First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²The Alfred Hospital, Melbourne, Australia, ³Sheba Medical Center, Tel-aviv, Israel, ⁴University Hospital of Saint Etienne, Saint Etienne, France

¹Takeda Development Centre Europe Ltd., Evidence and Value Generation, London, UK, ²Evidera, Real World Evidence, Waltham, MA, USA, ³Evidera, Real World Evidence, London, UK

¹Immundiagnostik AG, Bensheim, Germany, ²Interdisciplinary Crohn Colitis Centre Rhein-Main, Frankfurt/Main, Germany, ³DGD Clinics Sachsenhausen, Frankfurt/Main, Germany

¹Pfizer Inc., Biosimilars Development, New York, USA, ²Global Clinical Development, Biopharmaceuticals, Hexal AG (a Sandoz company), Holzkirchen, Germany, ³Pfizer Inc., Andover, USA

¹Centro Hospitalar Tondela-Viseu, Gastroenterology, Viseu, Portugal, ²Centro Hospitalar Tondela-Viseu, Pathology, Viseu, Portugal